product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse Amphiregulin Antibody
catalog :
AF989
quantity :
100 ug (also 25 ug)
price :
529 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
mouse
application :
western blot, ELISA, immunohistochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 14
Reference
Walkenhorst M, Sonner J, Meurs N, Engler J, Bauer S, Winschel I, et al. Protective effect of TCR-mediated MAIT cell activation during experimental autoimmune encephalomyelitis. Nat Commun. 2024;15:9287 pubmed publisher
Loffredo L, Kaiser K, Kornberg A, Rao S, de Los Santos Alexis K, Han A, et al. An amphiregulin reporter mouse enables transcriptional and clonal expansion analysis of reparative lung Treg cells. bioRxiv. 2024;: pubmed publisher
Liu J, Pan L, Hong W, Chen S, Bai P, Luo W, et al. GPR174 knockdown enhances blood flow recovery in hindlimb ischemia mice model by upregulating AREG expression. Nat Commun. 2022;13:7519 pubmed publisher
Tsou A, Yano H, Parkhurst C, Mahlak xf5 iv T, Chu C, Zhang W, et al. Neuropeptide regulation of non-redundant ILC2 responses at barrier surfaces. Nature. 2022;611:787-793 pubmed publisher
Agaronyan K, Sharma L, Vaidyanathan B, Glenn K, Yu S, Annicelli C, et al. Tissue remodeling by an opportunistic pathogen triggers allergic inflammation. Immunity. 2022;55:895-911.e10 pubmed publisher
Buelow L, Hoji A, Tat K, Schroeder Carter L, Carroll D, Cook Mills J. Mechanisms for Alternaria alternata Function in the Skin During Induction of Peanut Allergy in Neonatal Mice With Skin Barrier Mutations. Front Allergy. 2021;2:677019 pubmed publisher
Bu J, Huang S, Wang J, Xia T, Liu H, You Y, et al. The GABAA Receptor Influences Pressure Overload-Induced Heart Failure by Modulating Macrophages in Mice. Front Immunol. 2021;12:670153 pubmed publisher
Harb H, Benamar M, Lai P, Contini P, Griffith J, Crestani E, et al. Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections. Immunity. 2021;54:1186-1199.e7 pubmed publisher
Bikbov M, Khalimov T, Cerrada Gimenez M, Ragauskas S, Kalesnykas G, Jonas J. Compatibility of intravitreally applied epidermal growth factor and amphiregulin. Int Ophthalmol. 2021;41:2053-2063 pubmed publisher
Shime H, Odanaka M, Tsuiji M, Matoba T, Imai M, Yasumizu Y, et al. Proenkephalin+ regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function. Proc Natl Acad Sci U S A. 2020;117:20696-20705 pubmed publisher
Dong W, Liu L, Dou Y, Xu M, Liu T, Wang S, et al. Deoxycholic acid activates epidermal growth factor receptor and promotes intestinal carcinogenesis by ADAM17-dependent ligand release. J Cell Mol Med. 2018;22:4263-4273 pubmed publisher
Taverna S, Pucci M, Giallombardo M, Di Bella M, Santarpia M, Reclusa P, et al. Amphiregulin contained in NSCLC-exosomes induces osteoclast differentiation through the activation of EGFR pathway. Sci Rep. 2017;7:3170 pubmed publisher
Fujiu K, Shibata M, Nakayama Y, Ogata F, Matsumoto S, Noshita K, et al. A heart-brain-kidney network controls adaptation to cardiac stress through tissue macrophage activation. Nat Med. 2017;23:611-622 pubmed publisher
Jiang W, Song H, Li S, Guo B, Wu J, Li G, et al. Amphiregulin Antibody and Reduction of Axial Elongation in Experimental Myopia. EBioMedicine. 2017;17:134-144 pubmed publisher
product information
master code :
AF989
SKU :
AF989
product name :
Mouse Amphiregulin Antibody
unit size :
100 ug (also 25 ug)
description :
The Mouse Amphiregulin Antibody from R&D Systems is a goat polyclonal antibody to Amphiregulin. This antibody reacts with guinea pig,mouse,transgenic mouse. The Mouse Amphiregulin Antibody has been validated for the following applications: Immunohistochemistry,In vivo assay,Western Blot,Neutralization,Flow Cytometry,Immunohistochemistry-Paraffin,ELISA Capture (Matched Antibody Pair).
target :
Amphiregulin
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
E. coli -derived recombinant mouse Amphiregulin, Ser94-Lys191, Accession # P31955
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Guinea Pig,Mouse,Transgenic Mouse
specificity :
Detects mouse Amphiregulin in ELISAs and Western Blots. In sandwich immunoassays, less than 1% cross-reactivity with recombinant human Amphiregulin is observed.
gene symbol :
AREG
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Detection of Recombinant Human and Mouse Amphiregulin antibody by Western Blot.
accessionNumbers :
P31955
applications :
In vivo assay,Western Blot,Neutralization,Flow Cytometry,Immunohistochemistry,Immunohistochemistry-Paraffin,ELISA Capture (Matched Antibody Pair)
USD :
529 USD
alt names :
amphiregulin, AR, AREG, AREGB, Colorectum cell-derived growth factor, CRDGF, MGC13647, schwannoma-derived growth factor, SDGF
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.