product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse TIMP-1 Antibody
catalog :
AF980
quantity :
100 ug (also 25 ug)
price :
519 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
R&D Systems product webpage
citations: 14
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; 1:750; loading ...; fig 4e
Fleming Martinez A, D xf6 ppler H, Bastea L, Edenfield B, Liou G, Storz P. Ym1+ macrophages orchestrate fibrosis, lesion growth, and progression during development of murine pancreatic cancer. iScience. 2022;25:104327 pubmed publisher
Varga A, Németh I, Kemeny L, Varga J, Tiszlavicz L, Kumar D, et al. Elevated Serum Gastrin Is Associated with Melanoma Progression: Putative Role in Increased Migration and Invasion of Melanoma Cells. Int J Mol Sci. 2023;24: pubmed publisher
Oh K, Lee G, Kim H, Park J, Shin E, Kim E. Regorafenib prevents the development of emphysema in a murine elastase model. BMB Rep. 2023;56:439-444 pubmed
Piekna Przybylska D, Na D, Zhang J, Baker C, Ashton J, White P. Single cell RNA sequencing analysis of mouse cochlear supporting cell transcriptomes with activated ERBB2 receptor indicates a cell-specific response that promotes CD44 activation. Front Cell Neurosci. 2022;16:1096872 pubmed publisher
Coleman C, Stanley B, Lang C. Enrichment of Newly Synthesized Proteins following treatment of C2C12 Myotubes with Endotoxin and Interferon-γ. Inflammation. 2022;45:1313-1331 pubmed publisher
Sengupta S, Addya S, Biswas D, Banerjee P, Sarma J. Matrix metalloproteinases and tissue inhibitors of metalloproteinases in murine β-coronavirus-induced neuroinflammation. Virology. 2022;566:122-135 pubmed publisher
Hermann C, Schoeps B, Eckfeld C, Munkhbaatar E, Kniep L, Prokopchuk O, et al. TIMP1 expression underlies sex disparity in liver metastasis and survival in pancreatic cancer. J Exp Med. 2021;218: pubmed publisher
Yang H, Zhou T, Sorenson C, Sheibani N, Liu B. Myeloid-Derived TSP1 (Thrombospondin-1) Contributes to Abdominal Aortic Aneurysm Through Suppressing Tissue Inhibitor of Metalloproteinases-1. Arterioscler Thromb Vasc Biol. 2020;40:e350-e366 pubmed publisher
Angioni R, Liboni C, Herkenne S, Sánchez Rodríguez R, Borile G, Marcuzzi E, et al. CD73+ extracellular vesicles inhibit angiogenesis through adenosine A2B receptor signalling. J Extracell Vesicles. 2020;9:1757900 pubmed publisher
Dong J, Ma Q. In Vivo Activation and Pro-Fibrotic Function of NF-κB in Fibroblastic Cells During Pulmonary Inflammation and Fibrosis Induced by Carbon Nanotubes. Front Pharmacol. 2019;10:1140 pubmed publisher
Duarte S, Matian P, Ma S, Busuttil R, Coito A. Adeno-Associated Virus-Mediated Gene Transfer of Tissue Inhibitor of Metalloproteinases-1 Impairs Neutrophil Extracellular Trap Formation and Ameliorates Hepatic Ischemia and Reperfusion Injury. Am J Pathol. 2018;188:1820-1832 pubmed publisher
Giebeler N, Schönefuß A, Landsberg J, Tuting T, Mauch C, Zigrino P. Deletion of ADAM-9 in HGF/CDK4 mice impairs melanoma development and metastasis. Oncogene. 2017;36:5058-5067 pubmed publisher
Zanotti L, Angioni R, Calì B, Soldani C, Ploia C, Moalli F, et al. Mouse mesenchymal stem cells inhibit high endothelial cell activation and lymphocyte homing to lymph nodes by releasing TIMP-1. Leukemia. 2016;30:1143-54 pubmed publisher
Fan M, Zhu Q, Li H, Ra H, Majumdar S, Gulick D, et al. Fibroblast Activation Protein (FAP) Accelerates Collagen Degradation and Clearance from Lungs in Mice. J Biol Chem. 2016;291:8070-89 pubmed publisher
product information
master code :
AF980
SKU :
AF980
product name :
Mouse TIMP-1 Antibody
unit size :
100 ug (also 25 ug)
description :
The Mouse TIMP-1 Antibody from R&D Systems is a goat polyclonal antibody to TIMP-1. This antibody reacts with human,mouse,transgenic mouse. The Mouse TIMP-1 Antibody has been validated for the following applications: Western Blot,Immunohistochemistry,Immunocytochemistry,In vivo assay,Electron Microscopy,Neutralization,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunoprecipitation.
target :
TIMP-1
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse TIMP-1, Cys25-Arg205, Accession # P12032
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Transgenic Mouse
specificity :
Detects mouse TIMP-1 in direct ELISAs and Western blots. In direct ELISAs, approximately 15% cross-reactivity with recombinant rat TIMP-1 is observed, less than 5% cross-reactivity with recombinant human (rh) TIMP-1 is observed, and less than 1% cross-reactivity with rhTIMP-2 is observed.
gene symbol :
TIMP1
top caption :
TIMP-1 antibody in Mouse Ovary by Immunohistochemistry (IHC-Fr).
accessionNumbers :
P12032
applications :
Western Blot,Immunohistochemistry,Immunocytochemistry,In vivo assay,Electron Microscopy,Neutralization,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunoprecipitation
USD :
519 USD
alt names :
CLGI, Collagenase inhibitor, collagenase inhibitor), EPATIMP-1, EPO, erythroid potentiating activity, Erythroid-potentiating activity, Fibroblast collagenase inhibitor, FLJ90373, HCI, metalloproteinase inhibitor 1, TIMP metallopeptidase inhibitor 1, TIMP1, TIMPtissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, Tissue inhibitor of metalloproteinases 1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.