Human/Mouse TIMP-2 Antibody | R&D Systems AF971 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse TIMP-2 Antibody

catalog :

AF971

quantity :

100 ug (also 25 ug)

price :

489 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, neutralization, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, immunohistochemistry - free floating section, immunohistochemistry knockout validation

more info or order :

R&D Systems product webpage

citations: 8

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry knockout validation; mouse; 1:100; loading ...; fig s7e immunohistochemistry - free floating section; mouse; 1:100; loading ...; fig s7e	Castellano J, Mosher K, Abbey R, McBride A, James M, Berdnik D, et al. Human umbilical cord plasma proteins revitalize hippocampal function in aged mice. Nature. 2017;544:488-492 pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 2b	Zarb Y, Sridhar S, Nassiri S, Utz S, Schaffenrath J, Maheshwari U, et al. Microglia control small vessel calcification via TREM2. Sci Adv. 2021;7: pubmed publisher
	Varga A, Németh I, Kemeny L, Varga J, Tiszlavicz L, Kumar D, et al. Elevated Serum Gastrin Is Associated with Melanoma Progression: Putative Role in Increased Migration and Invasion of Melanoma Cells. Int J Mol Sci. 2023;24: pubmed publisher
	Xu L, Nirwane A, Xu T, Kang M, Devasani K, Yao Y. Fibroblasts repair blood-brain barrier damage and hemorrhagic brain injury via TIMP2. Cell Rep. 2022;41:111709 pubmed publisher
	Ferdoushi A, Li X, Griffin N, Faulkner S, Jamaluddin M, Gao F, et al. Schwann Cell Stimulation of Pancreatic Cancer Cells: A Proteomic Analysis. Front Oncol. 2020;10:1601 pubmed publisher
	Baker Williams A, Hashmi F, Budzyński M, Woodford M, Gleicher S, Himanen S, et al. Co-chaperones TIMP2 and AHA1 Competitively Regulate Extracellular HSP90:Client MMP2 Activity and Matrix Proteolysis. Cell Rep. 2019;28:1894-1906.e6 pubmed publisher
	Lu D, Liao Y, Zhu S, Chen Q, Xie D, Liao J, et al. Bone-derived Nestin-positive mesenchymal stem cells improve cardiac function via recruiting cardiac endothelial cells after myocardial infarction. Stem Cell Res Ther. 2019;10:127 pubmed publisher
	Saunders W, Bohnsack B, Faske J, Anthis N, Bayless K, Hirschi K, et al. Coregulation of vascular tube stabilization by endothelial cell TIMP-2 and pericyte TIMP-3. J Cell Biol. 2006;175:179-91 pubmed

product information

master code :

AF971

SKU :

AF971

product name :

Human/Mouse TIMP-2 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human/Mouse TIMP-2 Antibody from R&D Systems is a goat polyclonal antibody to TIMP-2. This antibody reacts with human,mouse. The Human/Mouse TIMP-2 Antibody has been validated for the following applications: Immunoprecipitation,Western Blot,Neutralization,Functional Assay,Immunohistochemistry,Immunohistochemistry-Frozen,Knockout Validated,Dual RNAscope ISH-IHC Compatible.

target :

TIMP-2

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Chinese hamster ovary cell line CHO-derived recombinant human TIMP-2, Cys27-Pro220, Accession # P16035

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse

specificity :

Detects human and mouse TIMP-2 in direct ELISAs and Western blots. In direct ELISAs, less than 2% cross-reactivity with recombinant human TIMP-4 is observed.

gene symbol :

TIMP2

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Detection of Human TIMP-2 antibody by Western Blot.

accessionNumbers :

P16035

applications :

Immunoprecipitation,Western Blot,Neutralization,Functional Assay,Immunohistochemistry,Immunohistochemistry-Frozen,Knockout Validated,Dual RNAscope ISH-IHC Compatible

USD :

489 USD

alt names :

CSC-21Ktissue inhibitor of metalloproteinase 2, metalloproteinase inhibitor 2, TIMP metallopeptidase inhibitor 2, TIMP2, TIMP-2, Tissue inhibitor of metalloproteinases 2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage