product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human GDF-15 Antibody
catalog :
AF957
quantity :
100 ug (also 25 ug)
price :
519 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, neutralization, immunohistochemistry - paraffin section
more info or order :
R&D Systems product webpage
citations: 7
Reference
Chang C, Cheng Y, Kamlapurkar S, White S, Tang P, Elhaw A, et al. GPX3 supports ovarian cancer tumor progression in vivo and promotes expression of GDF15. bioRxiv. 2024;: pubmed publisher
Semina S, Alejo L, Chopra S, Kansara N, Kastrati I, Sartorius C, et al. Identification of a novel ER-NFĸB-driven stem-like cell population associated with relapse of ER+ breast tumors. Breast Cancer Res. 2022;24:88 pubmed publisher
Rybicki B, Sadasivan S, Chen Y, Kravtsov O, Palangmonthip W, Arora K, et al. Growth and differentiation factor 15 and NF-κB expression in benign prostatic biopsies and risk of subsequent prostate cancer detection. Cancer Med. 2021;10:3013-3025 pubmed publisher
Christenson J, O Neill K, Williams M, Spoelstra N, Jones K, Trahan G, et al. Activity of Combined Androgen Receptor Antagonism and Cell Cycle Inhibition in Androgen Receptor Positive Triple Negative Breast Cancer. Mol Cancer Ther. 2021;20:1062-1071 pubmed publisher
Krawczyk M, Zimmermann S, Hess G, Holz R, Dauer M, Raedle J, et al. Panel of three novel serum markers predicts liver stiffness and fibrosis stages in patients with chronic liver disease. PLoS ONE. 2017;12:e0173506 pubmed publisher
Sasahara A, Tominaga K, Nishimura T, Yano M, Kiyokawa E, Noguchi M, et al. An autocrine/paracrine circuit of growth differentiation factor (GDF) 15 has a role for maintenance of breast cancer stem-like cells. Oncotarget. 2017;8:24869-24881 pubmed publisher
Muralidharan A, Maddala R, Skiba N, Rao P. Growth Differentiation Factor-15-Induced Contractile Activity and Extracellular Matrix Production in Human Trabecular Meshwork Cells. Invest Ophthalmol Vis Sci. 2016;57:6482-6495 pubmed publisher
product information
brand :
R&D Systems
master code :
AF957
SKU :
AF957
product name :
Human GDF-15 Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Human GDF-15 Antibody from R&D Systems is a goat polyclonal antibody to GDF-15. This antibody reacts with human. The Human GDF-15 Antibody has been validated for the following applications: Western Blot,ELISA Development,Neutralization,Immunohistochemistry,Immunohistochemistry-Paraffin,Simple Western.
target :
GDF-15
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 0.5 ug/mL, Simple Western 5 ug/mL
host :
Goat
immunogen :
Chinese hamster ovary cell line CHO-derived recombinant human GDF-15, Ala197-Ile308, Accession # Q99988
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human
specificity :
Detects human GDF-15 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 65% cross-reactivity with recombinant mouse (rm) GDF-15 is observed, and less than 1% cross-reactivity with rmGDF-1, rmGDF-3, and rmGDF-11 is observed.
gene symbol :
GDF15
top caption :
Detection of Human GDF-15 antibody by Western Blot.
accessionNumbers :
Q99988
applications :
Simple Western,ELISA Development,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Neutralization
USD :
519 USD
alt names :
GDF15, growth differentiation factor 15, growth/differentiation factor 15, Macrophage inhibitory cytokine 1, MIC-1, MIC-1NSAID-activated gene 1 protein, MIC1Prostate differentiation factor, NAG-1, NAG-1NSAID-regulated gene 1 protein, NSAID (nonsteroidal inflammatory drug)-activated protein 1, PDF, PDFGDF-15, PLAB, PLABNRG-1, Placental bone morphogenetic protein, Placental TGF-beta, PTGF-beta, PTGFBPTGF-beta
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.