Human/Mouse ADAM9 Ectodomain Antibody | R&D Systems AF949 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse ADAM9 Ectodomain Antibody

catalog :

AF949

quantity :

100 ug (also 25 ug)

price :

479 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, flow cytometry

more info or order :

R&D Systems product webpage

citations: 9

Reference
Jotatsu Y, Sung S, Wu M, Takeda S, Hirata Y, Maeda K, et al. An Antibody of the Secreted Isoform of Disintegrin and Metalloprotease 9 (sADAM9) Inhibits Epithelial-Mesenchymal Transition and Migration of Prostate Cancer Cell Lines. Int J Mol Sci. 2024;25: pubmed publisher
Bazzone L, Zhu J, King M, Liu G, Guo Z, Mackay C, et al. ADAM9 promotes type I interferon-mediated innate immunity during encephalomyocarditis virus infection. Nat Commun. 2024;15:4153 pubmed publisher
Cheng W, Chang C, Lo C, Hsieh C, Kuo T, Tseng G, et al. Identification of theranostic factors for patients developing metastasis after surgery for early-stage lung adenocarcinoma. Theranostics. 2021;11:3661-3675 pubmed publisher
Abety A, Pach E, Giebeler N, Fromme J, Aramadhaka L, Mauch C, et al. Loss of ADAM9 Leads to Modifications of the Extracellular Matrix Modulating Tumor Growth. Biomolecules. 2020;10: pubmed publisher
Bazzone L, King M, Mackay C, Kyawe P, Meraner P, LINDSTROM D, et al. A Disintegrin and Metalloproteinase 9 Domain (ADAM9) Is a Major Susceptibility Factor in the Early Stages of Encephalomyocarditis Virus Infection. MBio. 2019;10: pubmed publisher
Mygind K, Störiko T, Freiberg M, Samsøe Petersen J, Schwarz J, Andersen O, et al. Sorting nexin 9 (SNX9) regulates levels of the transmembrane ADAM9 at the cell surface. J Biol Chem. 2018;293:8077-8088 pubmed publisher
Lin C, Cho C, Bai S, Liu J, Kuo T, Wang L, et al. ADAM9 promotes lung cancer progression through vascular remodeling by VEGFA, ANGPT2, and PLAT. Sci Rep. 2017;7:15108 pubmed publisher
Giebeler N, Schönefuß A, Landsberg J, Tuting T, Mauch C, Zigrino P. Deletion of ADAM-9 in HGF/CDK4 mice impairs melanoma development and metastasis. Oncogene. 2017;36:5058-5067 pubmed publisher
Tam W, Au N, Ma C. The association between laminin and microglial morphology in vitro. Sci Rep. 2016;6:28580 pubmed publisher

product information

master code :

AF949

SKU :

AF949

product name :

Human/Mouse ADAM9 Ectodomain Antibody

unit size :

100 ug (also 25 ug)

description :

The Human/Mouse ADAM9 Ectodomain Antibody from R&D Systems is a goat polyclonal antibody to ADAM9. This antibody reacts with human,mouse. The Human/Mouse ADAM9 Ectodomain Antibody has been validated for the following applications: Flow Cytometry,Western Blot,Neutralization,Immunohistochemistry,Immunocytochemistry,Immunoprecipitation,CyTOF-ready,Knockout Validated.

target :

ADAM9

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse ADAM9, Ala206-Asp697, Accession # Q61072

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse

specificity :

Detects mouse ADAM9 Ectodomain in direct ELISAs and Western blots. In Western blots no cross-reactivity with the Ectodomain of recombinant mouse ADAM10 and rhADAM8, 15, and 17 (TACE) is observed.

gene symbol :

ADAM9

Antibody validation :

Knockout/Knockdown

top caption :

Detection of Human and Mouse ADAM9 antibody by Western Blot.

accessionNumbers :

Q61072

applications :

Flow Cytometry,Western Blot,Neutralization,Immunohistochemistry,Immunocytochemistry,Immunoprecipitation,CyTOF-ready,Knockout Validated

USD :

479 USD

alt names :

a disintegrin and metalloproteinase domain 9 (meltrin gamma), ADAM 9, ADAM metallopeptidase domain 9, ADAM metallopeptidase domain 9 (meltrin gamma), Cellular disintegrin-related protein, cone rod dystrophy 9, CORD9, disintegrin and metalloproteinase domain-containing protein 9, EC 3.4.24, EC 3.4.24.-, MCMP, MCMPMDC9KIAA0021Mltng, MDC9, Meltrin gamma, Meltrin-gamma, Metalloprotease/disintegrin/cysteine-rich protein 9, MLTNG, Myeloma cell metalloproteinase

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage