product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Desmoglein-2 Antibody
catalog :
AF947
quantity :
100 ug (also 25 ug)
price :
469 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse, rhesus macaque
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
R&D Systems product webpage
citations: 7
Reference
Myo Min K, Rojas Canales D, Penko D, DeNichilo M, Cockshell M, Ffrench C, et al. Desmoglein-2 is important for islet function and β-cell survival. Cell Death Dis. 2022;13:911 pubmed publisher
Lee E, Tyler R, Johnson D, Koh N, Ong B, Foo S, et al. High frequency of anti-DSG 2 antibodies in post COVID-19 serum samples. J Mol Cell Cardiol. 2022;170:121-123 pubmed publisher
Wang H, Germond A, Li C, Gil S, Kim J, Kiem H, et al. In vivo HSC transduction in rhesus macaques with an HDAd5/3+ vector targeting desmoglein 2 and transiently overexpressing cxcr4. Blood Adv. 2022;6:4360-4372 pubmed publisher
Kim J, Li C, Wang H, Kaviraj S, Singh S, Savergave L, et al. Translational development of a tumor junction opening technology. Sci Rep. 2022;12:7753 pubmed publisher
Kim J, Beidler P, Wang H, Li C, Quassab A, Coles C, et al. Desmoglein-2 as a prognostic and biomarker in ovarian cancer. Cancer Biol Ther. 2020;21:1154-1162 pubmed publisher
Franke W, Domke L, D xf6 rflinger Y, Zimbelmann R. The cell-cell junctions of mammalian testes. III. Absence of an endothelial cell layer covering the peritubular wall of the seminiferous tubules-an immunocytochemical correction of a 50-year-old error in the literature. Cell Tissue Res. 2020;379:75-92 pubmed publisher
Vragniau C, Hübner J, Beidler P, Gil S, Saydaminova K, Lu Z, et al. Studies on the Interaction of Tumor-Derived HD5 Alpha Defensins with Adenoviruses and Implications for Oncolytic Adenovirus Therapy. J Virol. 2017;91: pubmed publisher
product information
brand :
R&D Systems
catalog number base :
AF947
SKU :
AF947
product name :
Human Desmoglein-2 Antibody
units size :
100 ug (also 25 ug)
description :
The Human Desmoglein-2 Antibody from R&D Systems is a goat polyclonal antibody to Desmoglein-2. This antibody reacts with human,mouse,primate - macaca fascicularis (crab-eating monkey or cynomolgus macaque),primate - macaca mulatta (rhesus macaque),rhesus macaque. The Human Desmoglein-2 Antibody has been validated for the following applications: Flow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Simple Western,Immunocytochemistry,ELISA Capture.
target :
Desmoglein-2
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
all_available conjugate :
Unconjugated
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant human Desmoglein-2, Met1-Gly608, Accession # CAA81226
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque),Primate - Macaca mulatta (Rhesus Macaque),Rhesus Macaque
specificity :
Detects human Desmoglein-2 in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant human Desmoglein-1 is observed.
gene symbol :
DSG2
top caption :
Detection of Human Desmoglein-2 antibody by Western Blot.
accessionNumbers :
CAA81226
applications :
Flow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Simple Western,Immunocytochemistry,ELISA Capture
USD :
469 USD
alt names :
ARVC10, ARVD10, Cadherin family member 5, CDHF5, CDHF5MGC117034, CMD1BB, desmoglein 2, desmoglein-2, Desmoglein2, DSG2, HDGC, MGC117036, MGC117037
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.