Human Desmoglein-1 Antibody | R&D Systems AF944 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Desmoglein-1 Antibody

catalog :

AF944

quantity :

100 ug (also 25 ug)

price :

469 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry

more info or order :

R&D Systems product webpage

citations: 4

Reference
Hegazy M, Cohen Barak E, Koetsier J, Najor N, Arvanitis C, Sprecher E, et al. Proximity Ligation Assay for Detecting Protein-Protein Interactions and Protein Modifications in Cells and Tissues in Situ. Curr Protoc Cell Biol. 2020;89:e115 pubmed publisher
Dabelsteen S, Pallesen E, Marinova I, Nielsen M, Adamopoulou M, Rømer T, et al. Essential Functions of Glycans in Human Epithelia Dissected by a CRISPR-Cas9-Engineered Human Organotypic Skin Model. Dev Cell. 2020;54:669-684.e7 pubmed publisher
Valenzuela Iglesias A, Burks H, ARNETTE C, Yalamanchili A, Nekrasova O, Godsel L, et al. Desmoglein 1 Regulates Invadopodia by Suppressing EGFR/Erk Signaling in an Erbin-Dependent Manner. Mol Cancer Res. 2019;17:1195-1206 pubmed publisher
Nekrasova O, Harmon R, Broussard J, Koetsier J, Godsel L, Fitz G, et al. Desmosomal cadherin association with Tctex-1 and cortactin-Arp2/3 drives perijunctional actin polymerization to promote keratinocyte delamination. Nat Commun. 2018;9:1053 pubmed publisher

product information

master code :

AF944

SKU :

AF944

product name :

Human Desmoglein-1 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human Desmoglein-1 Antibody from R&D Systems is a goat polyclonal antibody to Desmoglein-1. This antibody reacts with human. The Human Desmoglein-1 Antibody has been validated for the following applications: Western Blot,Immunocytochemistry,Immunohistochemistry.

target :

Desmoglein-1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant human Desmoglein-1 extracellular domain, Glu50-His545, Accession # Q02413

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human

specificity :

Detects human Desmoglein-1 in direct ELISAs and Western blots. In direct ELISAs, less than 5% cross-reactivity with recombinant human (rh) Desmoglein-2 is observed and less than 1% cross-reactivity with rhDesmoglein-3, rhDesmoglein-4, and recombinant mouse Desmoglein-1 alpha is observed.

gene symbol :

DSG1

top caption :

Desmoglein-1 antibody in Human Skin by Immunohistochemistry (IHC-P).

accessionNumbers :

Q02413

applications :

Western Blot,Immunocytochemistry,Immunohistochemistry

USD :

469 USD

alt names :

Cadherin family member 4, CDHF4, CDHF4PPKS1, desmoglein 1, desmoglein-1, Desmoglein1, Desmosomal glycoprotein 1, DG1, DGI, DSG, DSG1, Pemphigus foliaceus antigen, SPPK1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage