Mouse SPARC Antibody | R&D Systems AF942 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse SPARC Antibody

catalog :

AF942

quantity :

100 ug (also 25 ug)

price :

499 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 22

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; loading ...; fig 6d	Kosinsky R, Saul D, Ammer Herrmenau C, Faubion W, Neesse A, Johnsen S. USP22 Suppresses SPARC Expression in Acute Colitis and Inflammation-Associated Colorectal Cancer. Cancers (Basel). 2021;13: pubmed publisher
	Le A, Fu M, Kumar R, Zacharias G, Garcia A. Astrocyte modulation of synaptic plasticity mediated by activity-dependent Sonic hedgehog signaling. bioRxiv. 2024;: pubmed publisher
	Niebergall E, Weekley D, Mazur A, Olszewski N, DeSchepper K, Radant N, et al. Abnormal Morphology and Synaptogenic Signaling in Astrocytes Following Prenatal Opioid Exposure. Cells. 2024;13: pubmed publisher
	Laddach A, Chng S, Lasrado R, Progatzky F, Shapiro M, Erickson A, et al. A branching model of lineage differentiation underpinning the neurogenic potential of enteric glia. Nat Commun. 2023;14:5904 pubmed publisher
	Song Y, Jamali N, Sorenson C, Sheibani N. Vitamin D Receptor Expression Limits the Angiogenic and Inflammatory Properties of Retinal Endothelial Cells. Cells. 2023;12: pubmed publisher
	Dos Santos Heringer L, Rios Carvalho J, Teixeira Oliveira J, Texeira Silva B, de Souza Aguiar Dos Santos D, Martinez Martinez Toledo A, et al. Altered excitatory and inhibitory neocortical circuitry leads to increased convulsive severity after pentylenetetrazol injection in an animal model of schizencephaly, but not of microgyria. Epilepsia Open. 2022;7:462-473 pubmed publisher
	Ammer Herrmenau C, Wolf L, Nasrin S, Ramu I, Roggiolani R, Goetze R, et al. Activity of acute pancreatitis is modified by secreted protein acidic and rich in cysteine ablation. United European Gastroenterol J. 2022;10:544-555 pubmed publisher
	MacDonald W, Swaminathan S, Heo J, Castillejos A, Hsueh J, Liu B, et al. Effect of SPARC Suppression in Mice, Perfused Human Anterior Segments, and Trabecular Meshwork Cells. Invest Ophthalmol Vis Sci. 2022;63:8 pubmed publisher
	Ghanemi A, Melouane A, Yoshioka M, St Amand J. Secreted Protein Acidic and Rich in Cysteine (Sparc) KO Leads to an Accelerated Ageing Phenotype Which Is Improved by Exercise Whereas SPARC Overexpression Mimics Exercise Effects in Mice. Metabolites. 2022;12: pubmed publisher
	Xie Y, Kuan A, Wang W, Herbert Z, Mosto O, Olukoya O, et al. Astrocyte-neuron crosstalk through Hedgehog signaling mediates cortical synapse development. Cell Rep. 2022;38:110416 pubmed publisher
	Shoneye T, Orrego A, Jarvis R, Men Y, Chiang M, Yang Y. Differential Proliferation and Maturation of Subcortical Astrocytes During Postnatal Development. Front Neurosci. 2020;14:435 pubmed publisher
	Falero Perez J, Sheibani N, Sorenson C. Bim expression modulates the pro-inflammatory phenotype of retinal astroglial cells. PLoS ONE. 2020;15:e0232779 pubmed publisher
	Praktiknjo S, Obermayer B, Zhu Q, Fang L, Liu H, Quinn H, et al. Tracing tumorigenesis in a solid tumor model at single-cell resolution. Nat Commun. 2020;11:991 pubmed publisher
	Ramu I, Buchholz S, Patzak M, Goetze R, Singh S, Richards F, et al. SPARC dependent collagen deposition and gemcitabine delivery in a genetically engineered mouse model of pancreas cancer. EBioMedicine. 2019;48:161-168 pubmed publisher
	Ximerakis M, Lipnick S, Innes B, Simmons S, Adiconis X, Dionne D, et al. Single-cell transcriptomic profiling of the aging mouse brain. Nat Neurosci. 2019;22:1696-1708 pubmed publisher
	Park J, Park J, Jun Y, Oh Y, Ryoo G, Jeong Y, et al. Expanding therapeutic utility of carfilzomib for breast cancer therapy by novel albumin-coated nanocrystal formulation. J Control Release. 2019;302:148-159 pubmed publisher
	Deckx S, Johnson D, Rienks M, Carai P, van Deel E, van der Velden J, et al. Extracellular SPARC increases cardiomyocyte contraction during health and disease. PLoS ONE. 2019;14:e0209534 pubmed publisher
	Falero Perez J, Song Y, Zhao Y, Teixeira L, Sorenson C, Sheibani N. Cyp1b1 expression impacts the angiogenic and inflammatory properties of liver sinusoidal endothelial cells. PLoS ONE. 2018;13:e0206756 pubmed publisher
	Jones E, Bernardinelli Y, Zarruk J, Chierzi S, Murai K. SPARC and GluA1-Containing AMPA Receptors Promote Neuronal Health Following CNS Injury. Front Cell Neurosci. 2018;12:22 pubmed publisher
	Morel L, Chiang M, Higashimori H, Shoneye T, Iyer L, Yelick J, et al. Molecular and Functional Properties of Regional Astrocytes in the Adult Brain. J Neurosci. 2017;37:8706-8717 pubmed publisher
	Riabov V, Yin S, Song B, Avdic A, Schledzewski K, Ovsiy I, et al. Stabilin-1 is expressed in human breast cancer and supports tumor growth in mammary adenocarcinoma mouse model. Oncotarget. 2016;7:31097-110 pubmed publisher
	Tseng C, Kolonin M. Proteolytic Isoforms of SPARC Induce Adipose Stromal Cell Mobilization in Obesity. Stem Cells. 2016;34:174-90 pubmed publisher

product information

master code :

AF942

SKU :

AF942

product name :

Mouse SPARC Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse SPARC Antibody from R&D Systems is a goat polyclonal antibody to SPARC. This antibody reacts with human,mouse,rat,transgenic mouse. The Mouse SPARC Antibody has been validated for the following applications: Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,Intracellular Staining by Flow Cytometry,CyTOF-ready.

target :

SPARC

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse SPARC/Osteonectin, Ala18-Ile302, Accession # P07214

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Rat,Transgenic Mouse

specificity :

Detects mouse SPARC in direct ELISAs and Western blots.

gene symbol :

SPARC

top caption :

Detection of Mouse SPARC antibody by Western Blot.

accessionNumbers :

P07214

applications :

Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,Intracellular Staining by Flow Cytometry,CyTOF-ready

USD :

499 USD

alt names :

Basement-membrane protein 40, BM-40, ONcysteine-rich protein, osteonectin, Secreted protein acidic and rich in cysteine, secreted protein, acidic, cysteine-rich (osteonectin)

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage