product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human MCAM/CD146 Antibody
catalog :
AF932
quantity :
100 ug (also 25 ug)
price :
499 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
R&D Systems product webpage
citations: 3
Reference
Feng R, Wang Y, Ramachandran V, Ma Q, May M, Li M, et al. Characterization of novel neutralizing mouse monoclonal antibody JM1-24-3 developed against MUC18 in metastatic melanoma. J Exp Clin Cancer Res. 2020;39:273 pubmed publisher
Kim E, Seo S, Shin H, Lee D, Kim J, Lee D. Platelet-Derived Growth Factor Receptor-Positive Pericytic Cells of White Adipose Tissue from Critical Limb Ischemia Patients Display Mesenchymal Stem Cell-Like Properties. Clin Orthop Surg. 2017;9:239-248 pubmed publisher
Zhang P, He D, Chen Z, Pan Q, Du F, Zang X, et al. Chemotherapy enhances tumor vascularization via Notch signaling-mediated formation of tumor-derived endothelium in breast cancer. Biochem Pharmacol. 2016;118:18-30 pubmed publisher
product information
brand :
R&D Systems
master code :
AF932
SKU :
AF932
product name :
Human MCAM/CD146 Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Human MCAM/CD146 Antibody from R&D Systems is a goat polyclonal antibody to MCAM/CD146. This antibody reacts with human,mouse. The Human MCAM/CD146 Antibody has been validated for the following applications: Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,Western Blot,Simple Western.
target :
MCAM/CD146
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 1 ug/mL, Simple Western 10 ug/mL, Immunohistochemistry 5-15 ug/mL, Immunocytochemistry 5-15 ug/mL
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant human MCAM/CD146, Met1-Gly559, Accession # AAA20824
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse
specificity :
Detects human MCAM/CD46 in Western blots and direct ELISAs. In direct ELISAs, less than 10% cross-reactivity with recombinant human (rh) ALCAM, rhBCAM, rhNCAM-L1, rhTROP-2 and recombinant mouse MCAM is observed.
gene symbol :
MCAM
top caption :
Detection of Human MCAM/CD146 antibody by Western Blot.
accessionNumbers :
AAA20824
applications :
Western Blot,Simple Western,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry
USD :
499 USD
alt names :
CD146, CD146 antigen, cell surface glycoprotein MUC18, Cell surface glycoprotein P1H12, L-Gicerin, melanoma adhesion molecule, melanoma cell adhesion moleculeS-endo 1 endothelial-associated antigen, Melanoma-associated antigen A32, Melanoma-associated antigen MUC18, MUC18, MUC18Gicerin
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.