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company name :
R&D Systems
product type :
antibody
product name :
Mouse MMP-9 Antibody
catalog :
AF909
quantity :
100 ug (also 25 ug)
price :
489 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 50
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:800; loading ...; fig s9a
Shi H, Yin Z, Koronyo Y, Fuchs D, Sheyn J, Davis M, et al. Regulating microglial miR-155 transcriptional phenotype alleviates Alzheimer's-induced retinal vasculopathy by limiting Clec7a/Galectin-3+ neurodegenerative microglia. Acta Neuropathol Commun. 2022;10:136 pubmed publisher
Jeong C, Lee C, Lee Y, Seo J, Wang W, Park K, et al. Ulmus macrocarpa Hance trunk bark extracts inhibit RANKL-induced osteoclast differentiation and prevent ovariectomy-induced osteoporosis in mice. J Ethnopharmacol. 2024;319:117285 pubmed publisher
Fu Y, Liu H, Li K, Wei P, Alam N, Deng J, et al. C-reactive protein deficiency ameliorates experimental abdominal aortic aneurysms. Front Immunol. 2023;14:1233807 pubmed publisher
Graça F, Stephan A, Minden Birkenmaier B, Shirinifard A, Wang Y, Demontis F, et al. Platelet-derived chemokines promote skeletal muscle regeneration by guiding neutrophil recruitment to injured muscles. Nat Commun. 2023;14:2900 pubmed publisher
Fu W, Liu H, Wei P, Xia C, Yu Q, Tian K, et al. Genetic deficiency of protein inhibitor of activated STAT3 suppresses experimental abdominal aortic aneurysms. Front Cardiovasc Med. 2023;10:1092555 pubmed publisher
Chakraborty A, Halder B, Mondal S, Barrett A, Zhi W, Csanyi G, et al. NADPH oxidase 1 in chronic pancreatitis-activated pancreatic stellate cells facilitates the progression of pancreatic cancer. Am J Cancer Res. 2023;13:118-142 pubmed
Crompton M, Ferguson J, Ramnath R, Onions K, Ogier A, Gamez M, et al. Mineralocorticoid receptor antagonism in diabetes reduces albuminuria by preserving the glomerular endothelial glycocalyx. JCI Insight. 2023;8: pubmed publisher
Karasaki K, Kokubo H, Bumdelger B, Kaji N, Sakai C, Ishida M, et al. Angiotensin II Type 1 Receptor Blocker Prevents Abdominal Aortic Aneurysm Progression in Osteoprotegerin-Deficient Mice via Upregulation of Angiotensin (1-7). J Am Heart Assoc. 2023;12:e027589 pubmed publisher
Yamasaki T, Horie T, Koyama S, Nakao T, Baba O, Kimura M, et al. Inhibition of microRNA-33b specifically ameliorates abdominal aortic aneurysm formation via suppression of inflammatory pathways. Sci Rep. 2022;12:11984 pubmed publisher
Liu H, Tian K, Xia C, Wei P, Xu B, Fu W, et al. Kunming mouse strain is less susceptible to elastase-induced abdominal aortic aneurysms. Animal Model Exp Med. 2022;5:72-80 pubmed publisher
Murthy S, Baruah S, Bowen J, Keck K, Wagner B, Buettner G, et al. TREM-1 is required for enhanced OpZ-induced superoxide generation following priming. J Leukoc Biol. 2022;112:457-473 pubmed publisher
Tian K, Xia C, Liu H, Xu B, Wei P, Fu W, et al. Temporal and Quantitative Analysis of Aortic Immunopathologies in Elastase-Induced Mouse Abdominal Aortic Aneurysms. J Immunol Res. 2021;2021:6297332 pubmed publisher
Yang G, Wang S, Zhang S, Liu Y, Liu X, Wang D, et al. A Protective Role of Tumor Necrosis Factor Superfamily-15 in Intracerebral Hemorrhage-Induced Secondary Brain Injury. ASN Neuro. 2021;13:17590914211038441 pubmed publisher
Fraccarollo D, Neuser J, M xf6 ller J, Riehle C, Galuppo P, Bauersachs J. Expansion of CD10neg neutrophils and CD14+HLA-DRneg/low monocytes driving proinflammatory responses in patients with acute myocardial infarction. elife. 2021;10: pubmed publisher
Baik S, Lee J, Jeon E, Park B, Kim D, Song J, et al. Diving beetle-like miniaturized plungers with reversible, rapid biofluid capturing for machine learning-based care of skin disease. Sci Adv. 2021;7: pubmed publisher
Hasegawa T, Venkata Suresh V, Yahata Y, Nakano M, Suzuki S, Suzuki S, et al. Inhibition of the CXCL9-CXCR3 axis suppresses the progression of experimental apical periodontitis by blocking macrophage migration and activation. Sci Rep. 2021;11:2613 pubmed publisher
Gantov M, Pagnotta P, Lotufo C, Rindone G, Riera M, Calvo J, et al. Beige adipocytes contribute to breast cancer progression. Oncol Rep. 2021;45:317-328 pubmed publisher
Campelj D, Timpani C, Petersen A, Hayes A, Goodman C, Rybalka E. The Paradoxical Effect of PARP Inhibitor BGP-15 on Irinotecan-Induced Cachexia and Skeletal Muscle Dysfunction. Cancers (Basel). 2020;12: pubmed publisher
Li K, Zhou Z, Li J, Xiang R. miR-146b Functions as an Oncogene in Oral Squamous Cell Carcinoma by Targeting HBP1. Technol Cancer Res Treat. 2020;19:1533033820959404 pubmed publisher
Zhang W, Cheng W, Parlato R, Guo X, Cui X, Dai C, et al. Nucleolar stress induces a senescence-like phenotype in smooth muscle cells and promotes development of vascular degeneration. Aging (Albany NY). 2020;12:22174-22198 pubmed publisher
Yang H, Zhou T, Sorenson C, Sheibani N, Liu B. Myeloid-Derived TSP1 (Thrombospondin-1) Contributes to Abdominal Aortic Aneurysm Through Suppressing Tissue Inhibitor of Metalloproteinases-1. Arterioscler Thromb Vasc Biol. 2020;40:e350-e366 pubmed publisher
Zheng Q, Dai X, Fang W, Zheng Y, Zhang J, Liu Y, et al. Overexpression of microRNA-367 inhibits angiogenesis in ovarian cancer by downregulating the expression of LPA1. Cancer Cell Int. 2020;20:476 pubmed publisher
Jeong S, Cho M, Ko N, Kim S, Jung I, Min J, et al. Deficiency of peroxiredoxin 2 exacerbates angiotensin II-induced abdominal aortic aneurysm. Exp Mol Med. 2020;52:1587-1601 pubmed publisher
Lu C, Lai S, Lee H, Chien H, Lan K, Chen K. Matrix metalloproteinases activation in Toxocara canis induced pulmonary pathogenesis. J Microbiol Immunol Infect. 2021;54:1147-1153 pubmed publisher
Yoshimura K, Aoki H, Teruyama C, Iijima M, Tsutsumi H, Kuroda S, et al. A Novel Hybrid Drug Delivery System for Treatment of Aortic Aneurysms. Int J Mol Sci. 2020;21: pubmed publisher
Osthues T, Zimmer B, Rimola V, Klann K, Schilling K, Mathoor P, et al. The Lipid Receptor G2A (GPR132) Mediates Macrophage Migration in Nerve Injury-Induced Neuropathic Pain. Cells. 2020;9: pubmed publisher
Gou X, Xue Y, Zheng H, Yang G, Chen S, Chen Z, et al. Gelatinases Cleave Dentin Sialoprotein Intracellularly. Front Physiol. 2020;11:686 pubmed publisher
Hui L, Nie Y, Li S, Guo M, Yang W, Huang R, et al. Matrix metalloproteinase 9 facilitates Zika virus invasion of the testis by modulating the integrity of the blood-testis barrier. PLoS Pathog. 2020;16:e1008509 pubmed publisher
Miteva K, Baptista D, Montecucco F, Asrih M, Burger F, Roth A, et al. Cardiotrophin-1 Deficiency Abrogates Atherosclerosis Progression. Sci Rep. 2020;10:5791 pubmed publisher
Kaminski A, Moore E, Daseke M, Valerio F, Flynn E, Lindsey M. The compendium of matrix metalloproteinase expression in the left ventricle of mice following myocardial infarction. Am J Physiol Heart Circ Physiol. 2020;318:H706-H714 pubmed publisher
Li S, Hayden E, Garcia V, Fuchs D, Sheyn J, Daley D, et al. Activated Bone Marrow-Derived Macrophages Eradicate Alzheimer's-Related Aβ42 Oligomers and Protect Synapses. Front Immunol. 2020;11:49 pubmed publisher
Nakajima K, Ono M, Radović U, Dizdarevic S, Tomizawa S, Kuroha K, et al. Lack of whey acidic protein (WAP) four-disulfide core domain protease inhibitor 2 (WFDC2) causes neonatal death from respiratory failure in mice. Dis Model Mech. 2019;12: pubmed publisher
Zhang H, Liao M, Cao M, Qiu Z, Yan X, Zhou Y, et al. ATRQβ-001 Vaccine Prevents Experimental Abdominal Aortic Aneurysms. J Am Heart Assoc. 2019;8:e012341 pubmed publisher
Wang W, Gao Y, Liu H, Feng W, Li X, Guo J, et al. Eldecalcitol, an active vitamin D analog, effectively prevents cyclophosphamide-induced osteoporosis in rats. Exp Ther Med. 2019;18:1571-1580 pubmed publisher
Durán Laforet V, Fernández López D, García Culebras A, González Hijón J, Moraga A, Palma Tortosa S, et al. Delayed Effects of Acute Reperfusion on Vascular Remodeling and Late-Phase Functional Recovery After Stroke. Front Neurosci. 2019;13:767 pubmed publisher
Liu Y, Zhang Y, Hu M, Li Y, Cao X. Carnosic acid alleviates brain injury through NF‑κB‑regulated inflammation and Caspase‑3‑associated apoptosis in high fat‑induced mouse models. Mol Med Rep. 2019;20:495-504 pubmed publisher
Ochiai N, Nakachi Y, Yokoo T, Ichihara T, Eriksson T, Yonemoto Y, et al. Murine osteoclasts secrete serine protease HtrA1 capable of degrading osteoprotegerin in the bone microenvironment. Commun Biol. 2019;2:86 pubmed publisher
Kato H, Duarte S, Miller M, Busuttil R, Coito A. Overproduction of Tenascin-C Driven by Lipid Accumulation in the Liver Aggravates Hepatic Ischemia/Reperfusion Injury in Steatotic Mice. Liver Transpl. 2019;25:288-301 pubmed publisher
Kniewallner K, Foidl B, Humpel C. Platelets isolated from an Alzheimer mouse damage healthy cortical vessels and cause inflammation in an organotypic ex vivo brain slice model. Sci Rep. 2018;8:15483 pubmed publisher
Duarte S, Matian P, Ma S, Busuttil R, Coito A. Adeno-Associated Virus-Mediated Gene Transfer of Tissue Inhibitor of Metalloproteinases-1 Impairs Neutrophil Extracellular Trap Formation and Ameliorates Hepatic Ischemia and Reperfusion Injury. Am J Pathol. 2018;188:1820-1832 pubmed publisher
Hara T, Phuong P, Fukuda D, Yamaguchi K, Murata C, Nishimoto S, et al. Protease-Activated Receptor-2 Plays a Critical Role in Vascular Inflammation and Atherosclerosis in Apolipoprotein E-Deficient Mice. Circulation. 2018;: pubmed publisher
Huang X, Yue Z, Wu J, Chen J, Wang S, Wu J, et al. MicroRNA-21 Knockout Exacerbates Angiotensin II-Induced Thoracic Aortic Aneurysm and Dissection in Mice With Abnormal Transforming Growth Factor-β-SMAD3 Signaling. Arterioscler Thromb Vasc Biol. 2018;38:1086-1101 pubmed publisher
Liu L, Li H, Nie S, Shen M, Hu J, Xie M. Tea Polysaccharide Prevents Colitis-Associated Carcinogenesis in Mice by Inhibiting the Proliferation and Invasion of Tumor Cells. Int J Mol Sci. 2018;19: pubmed publisher
Singh S, Houng A, Reed G. Matrix Metalloproteinase-9 Mediates the Deleterious Effects of α2-Antiplasmin on Blood-Brain Barrier Breakdown and Ischemic Brain Injury in Experimental Stroke. Neuroscience. 2018;376:40-47 pubmed publisher
Vandooren J, Swinnen W, Ugarte Berzal E, Boon L, Dorst D, Martens E, et al. Endotoxemia shifts neutrophils with TIMP-free gelatinase B/MMP-9 from bone marrow to the periphery and induces systematic upregulation of TIMP-1. Haematologica. 2017;102:1671-1682 pubmed publisher
Thiele N, Wirth J, Steins D, Koop A, Ittrich H, Lohse A, et al. TIMP-1 is upregulated, but not essential in hepatic fibrogenesis and carcinogenesis in mice. Sci Rep. 2017;7:714 pubmed publisher
Shimoda M, Yoshida H, Mizuno S, Hirozane T, Horiuchi K, Yoshino Y, et al. Hyaluronan-Binding Protein Involved in Hyaluronan Depolymerization Controls Endochondral Ossification through Hyaluronan Metabolism. Am J Pathol. 2017;187:1162-1176 pubmed publisher
Liao M, Yang P, Wang F, Berceli S, Ali Y, Chan K, et al. Smooth muscle cell-specific Tgfbr1 deficiency attenuates neointimal hyperplasia but promotes an undesired vascular phenotype for injured arteries. Physiol Rep. 2016;4: pubmed
Huuskonen M, Loppi S, Dhungana H, Keksa Goldsteine V, Lemarchant S, Korhonen P, et al. Bexarotene targets autophagy and is protective against thromboembolic stroke in aged mice with tauopathy. Sci Rep. 2016;6:33176 pubmed publisher
Gounko N, Martens E, Opdenakker G, Rybakin V. Thymocyte development in the absence of matrix metalloproteinase-9/gelatinase B. Sci Rep. 2016;6:29852 pubmed publisher
product information
brand :
R&D Systems
master code :
AF909
SKU :
AF909
product name :
Mouse MMP-9 Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Mouse MMP-9 Antibody from R&D Systems is a goat polyclonal antibody to MMP-9. This antibody reacts with complex species category,human,mouse,transgenic mouse. The Mouse MMP-9 Antibody has been validated for the following applications: Immunohistochemistry,Flow Cytometry,Immunoprecipitation,Western Blot,Electron Microscopy,Neutralization,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,Simple Western.
target :
MMP-9
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot .25 ug/mL, Simple Western 5 ug/mL, Immunohistochemistry 5-15 ug/mL, Immunoprecipitation 25 ug/mL, Immunocytochemistry 5-15 ug/mL
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse MMP-9, Ala20-Pro730, Accession # P41245
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Complex Species Category,Human,Mouse,Transgenic Mouse
specificity :
Detects mouse MMP-9 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 10% cross-reactivity with recombinant human (rh) MMP-9 is observed and less than 2% cross-reactivity with rhMMP-1, -2, -3, -7, -8, -10, -12, and -13 is observed.
gene symbol :
MMP9
top caption :
Detection of Mouse MMP-9 antibody by Western Blot.
accessionNumbers :
P41245
applications :
Simple Western,Flow Cytometry,Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Electron Microscopy,Neutralization,Immunocytochemistry
USD :
489 USD
alt names :
92 kDa gelatinase, 92 kDa type IV collagenase, CLG4B, EC 3.4.24, EC 3.4.24.35, Gelatinase B, GELB, macrophage gelatinase, MANDP2, matrix metallopeptidase 9, matrix metalloproteinase 9, matrix metalloproteinase-9, MMP9, MMP-9, type V collagenase
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.