product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse/Rat Contactin-1 Antibody
catalog :
AF904
quantity :
100 ug (also 25 ug)
price :
509 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation
more info or order :
R&D Systems product webpage
citations: 12
Reference
Ogawa Y, Lim B, George S, Oses Prieto J, Rasband J, Eshed Eisenbach Y, et al. Antibody-directed extracellular proximity biotinylation reveals that Contactin-1 regulates axo-axonic innervation of axon initial segments. Nat Commun. 2023;14:6797 pubmed publisher
Taieb G, Jentzer A, Vegezzi E, Lleix xe0 C, Illa I, Querol L, et al. Effect of monovalency on anti-contactin-1 IgG4. Front Immunol. 2023;14:1021513 pubmed publisher
Ogawa Y, Lim B, George S, Oses Prieto J, Rasband J, Eshed Eisenbach Y, et al. Antibody-directed extracellular proximity biotinylation reveals Contactin-1 regulates axo-axonic innervation of axon initial segments. bioRxiv. 2023;: pubmed publisher
Fehmi J, Davies A, Antonelou M, Keddie S, Pikkupeura S, Querol L, et al. Contactin-1 links autoimmune neuropathy and membranous glomerulonephritis. PLoS ONE. 2023;18:e0281156 pubmed publisher
Cifuentes Diaz C, Canali G, Garcia M, Druart M, Manett T, Savariradjane M, et al. Differential impacts of Cntnap2 heterozygosity and Cntnap2 null homozygosity on axon and myelinated fiber development in mouse. Front Neurosci. 2023;17:1100121 pubmed publisher
Chang K, Agrawal I, Vainshtein A, Ho W, Xin W, Tucker Kellogg G, et al. TDP-43 maximizes nerve conduction velocity by repressing a cryptic exon for paranodal junction assembly in Schwann cells. elife. 2021;10: pubmed publisher
Lecluze E, Rolland A, Filis P, Evrard B, Leverrier Penna S, Maamar M, et al. Dynamics of the transcriptional landscape during human fetal testis and ovary development. Hum Reprod. 2020;35:1099-1119 pubmed publisher
Manso C, Querol L, Lleixà C, Poncelet M, Mekaouche M, Vallat J, et al. Anti-Neurofascin-155 IgG4 antibodies prevent paranodal complex formation in vivo. J Clin Invest. 2019;129:2222-2236 pubmed publisher
Stojic A, Bojcevski J, Williams S, Diem R, Fairless R. Early Nodal and Paranodal Disruption in Autoimmune Optic Neuritis. J Neuropathol Exp Neurol. 2018;77:361-373 pubmed publisher
Montani L, Pereira J, Norrmen C, Pohl H, Tinelli E, Trötzmüller M, et al. De novo fatty acid synthesis by Schwann cells is essential for peripheral nervous system myelination. J Cell Biol. 2018;217:1353-1368 pubmed publisher
Querol L, Siles A, Alba Rovira R, Jáuregui A, Devaux J, Faivre Sarrailh C, et al. Antibodies against peripheral nerve antigens in chronic inflammatory demyelinating polyradiculoneuropathy. Sci Rep. 2017;7:14411 pubmed publisher
Martin P, Cifuentes Diaz C, Devaux J, Garcia M, Bureau J, Thomasseau S, et al. Schwannomin-interacting Protein 1 Isoform IQCJ-SCHIP1 Is a Multipartner Ankyrin- and Spectrin-binding Protein Involved in the Organization of Nodes of Ranvier. J Biol Chem. 2017;292:2441-2456 pubmed publisher
product information
brand :
R&D Systems
master code :
AF904
SKU :
AF904
product name :
Human/Mouse/Rat Contactin-1 Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Human/Mouse/Rat Contactin-1 Antibody from R&D Systems is a goat polyclonal antibody to Contactin-1. This antibody reacts with human,mouse,rat. The Human/Mouse/Rat Contactin-1 Antibody has been validated for the following applications: Western Blot,Neutralization,Immunoprecipitation,Immunohistochemistry,Immunocytochemistry,Simple Western.
target :
Contactin-1
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 0.5 ug/mL, Simple Western 5 ug/mL, Immunohistochemistry 5-15 ug/mL, Neutralization 1-5 ug/mL
host :
Goat
immunogen :
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Contactin-1, Glu21-Ser993, Accession # CAA79696
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Rat
specificity :
Detects human Contactin-1 in direct ELISAs. Detects human, mouse, and rat Contactin-1 in Western blots.
gene symbol :
CNTN1
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Contactin-1 antibody in Human Dorsal Root Ganglia by Immunohistochemistry (IHC-P).
accessionNumbers :
CAA79696
applications :
Simple Western,Immunohistochemistry,Immunoprecipitation,Western Blot,Neutralization,Immunocytochemistry
USD :
509 USD
alt names :
CNTN1, contactin 1, contactin-1, Contactin1, F11, F3, F3cam, Glycoprotein gp135, GP135, Neural cell surface protein F3
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.