product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Gas6 Antibody
catalog :
AF885
quantity :
100 ug (also 25 ug)
price :
499 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, neutralization, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 10
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; human; 1:25; loading ...; fig 2a
Huang Y, Happonen K, Burrola P, O Connor C, Hah N, Huang L, et al. Microglia use TAM receptors to detect and engulf amyloid β plaques. Nat Immunol. 2021;22:586-594 pubmed publisher
New Aaron M, Dagur R, Koganti S, Ganesan M, Wang W, Makarov E, et al. Alcohol and HIV-Derived Hepatocyte Apoptotic Bodies Induce Hepatic Stellate Cell Activation. Biology (Basel). 2022;11: pubmed publisher
Mikuteit M, Zsch xe4 bitz S, Erlmeier M, Autenrieth M, Weichert W, Hartmann A, et al. Growth Arrest-Specific 6 in Chromophobe Renal Cell Carcinoma. Oncology. 2022;100:536-541 pubmed publisher
Toboni M, Lomonosova E, Bruce S, Tankou J, Mullen M, Schab A, et al. Inhibition of AXL and VEGF-A Has Improved Therapeutic Efficacy in Uterine Serous Cancer. Cancers (Basel). 2021;13: pubmed publisher
Bellan M, Dimagli A, Piccinino C, Giubertoni A, Ianniello A, Grimoldi F, et al. Role of Gas6 and TAM Receptors in the Identification of Cardiopulmonary Involvement in Systemic Sclerosis and Scleroderma Spectrum Disorders. Dis Markers. 2020;2020:2696173 pubmed publisher
Ireland L, Luckett T, Schmid M, Mielgo A. Blockade of Stromal Gas6 Alters Cancer Cell Plasticity, Activates NK Cells, and Inhibits Pancreatic Cancer Metastasis. Front Immunol. 2020;11:297 pubmed publisher
Fujita K, Chen X, Homma H, Tagawa K, Amano M, Saito A, et al. Targeting Tyro3 ameliorates a model of PGRN-mutant FTLD-TDP via tau-mediated synaptic pathology. Nat Commun. 2018;9:433 pubmed publisher
Kanzaki R, Naito H, Kise K, Takara K, Eino D, Minami M, et al. Gas6 derived from cancer-associated fibroblasts promotes migration of Axl-expressing lung cancer cells during chemotherapy. Sci Rep. 2017;7:10613 pubmed publisher
Decker A, Jung Y, Cackowski F, Yumoto K, Wang J, Taichman R. Sympathetic Signaling Reactivates Quiescent Disseminated Prostate Cancer Cells in the Bone Marrow. Mol Cancer Res. 2017;15:1644-1655 pubmed publisher
Wu X, Ma W, Zhou Q, Yan H, Lim Z, Huang M, et al. AXL-GAS6 expression can predict for adverse prognosis in non-small cell lung cancer with brain metastases. J Cancer Res Clin Oncol. 2017;143:1947-1957 pubmed publisher
product information
brand :
R&D Systems
master code :
AF885
SKU :
AF885
product name :
Human Gas6 Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Human Gas6 Antibody from R&D Systems is a goat polyclonal antibody to Gas6. This antibody reacts with human,mouse. The Human Gas6 Antibody has been validated for the following applications: Binding Assay,ELISA (detection),ELISA Development,Western Blot,Neutralization,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,ELISA.
target :
Gas6
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 1 ug/mL, ELISA, Immunohistochemistry 5-15 ug/mL
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant human Gas6, Asp118-Ala678, Accession # NP_000811
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse
specificity :
Detects human Gas6 in direct ELISAs and Western blots. In direct ELISAs, approximately 30% cross-reactivity with recombinant mouse Gas6 is observed.
gene symbol :
GAS6
top caption :
Detection of Human Gas6 antibody by Western Blot.
accessionNumbers :
NP_000811
applications :
ELISA,Binding Assay,ELISA (detection),ELISA Development,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Neutralization,Immunocytochemistry
USD :
499 USD
alt names :
AXLLG, AXLLGAXL stimulatory factor, AXSFAXL receptor tyrosine kinase ligand, DKFZp666G247, FLJ34709, GAS-6, growth arrest-specific 6, growth arrest-specific protein 6
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.