product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Niemann-Pick Type C2/NPC2 Antibody
catalog :
AF8644
quantity :
100 ug (also 25 ug)
price :
449 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
R&D Systems product webpage
citations: 2
Reference
Pluvinage J, Sun J, Claes C, Flynn R, Haney M, Iram T, et al. The CD22-IGF2R interaction is a therapeutic target for microglial lysosome dysfunction in Niemann-Pick type C. Sci Transl Med. 2021;13:eabg2919 pubmed publisher
Yu S, Wang T, Wiggins K, Louie R, Merino E, Skinner C, et al. Lysosomal cholesterol accumulation contributes to the movement phenotypes associated with NUS1 haploinsufficiency. Genet Med. 2021;23:1305-1314 pubmed publisher
product information
master code :
AF8644
SKU :
AF8644
product name :
Human Niemann-Pick Type C2/NPC2 Antibody
unit size :
100 ug (also 25 ug)
description :
The Human Niemann-Pick Type C2/NPC2 Antibody from R&D Systems is a rabbit polyclonal antibody to Niemann-Pick type C2. This antibody reacts with human. The Human Niemann-Pick Type C2/NPC2 Antibody has been validated for the following applications: Western Blot,Immunocytochemistry,Immunohistochemistry.
target :
Niemann-Pick Type C2/NPC2
category :
Primary Antibodies
buffer :
Supplied as a solution in PBS containing BSA, Glycerol and Sodium Azide. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
conjugate :
Unconjugated
host :
Rabbit
immunogen :
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Niemann-Pick Type C2/NPC2, Glu20-Leu151, Accession # P61916
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human
specificity :
Detects human Niemann-Pick Type C2/NPC2 in direct ELISAs and Western blots.
gene symbol :
NPC2
top caption :
Detection of Human Niemann-Pick Type C2/NPC2 antibody by Western Blot.
accessionNumbers :
P61916
applications :
Immunohistochemistry,Western Blot,Immunocytochemistry
USD :
449 USD
alt names :
EDDM1, Epididymal Protein 1, epididymal secretory protein E1, HE1, HE1epididymal protein 1, Human epididymis-specific protein 1, MGC1333, Niemann-Pick disease type C2 protein, Niemann-Pick disease, type C2, NiemannPick Type C2, NPC2, NP-C2, tissue-specific secretory protein
storage :
12 months from date of receipt, -20 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after opening. 6 months, -20 ░C under sterile conditions after opening.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.