Mouse IL-18 R alpha /IL-1 R5 Antibody | R&D Systems AF856 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse IL-18 R alpha /IL-1 R5 Antibody

catalog :

AF856

quantity :

100 ug (also 25 ug)

price :

459 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

mouse

application :

western blot, immunohistochemistry, neutralization, flow cytometry, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 4

Reference
Zhang X, Luo S, Wang M, Huang Q, Fang W, Li J, et al. IL18 signaling causes islet β cell development and insulin secretion via different receptors on acinar and β cells. Dev Cell. 2022;57:1496-1511.e6 pubmed publisher
Howard J, Smith J, Fredman G, MacNamara K. IL-18R-mediated HSC quiescence and MLKL-dependent cell death limit hematopoiesis during infection-induced shock. Stem Cell Reports. 2021;16:2887-2899 pubmed publisher
Hayakawa T, Hata M, Kuwahara Otani S, Yagi H, Okamura H. Postnatal changes of interleukin-18 receptor immunoreactivity in neurons of the retrosplenial cortex in wild-type and interleukin-18 knock out mice. Okajimas Folia Anat Jpn. 2017;94:93-99 pubmed publisher
Kuwahara Otani S, Maeda S, Kobayashi K, Minato Y, Tanaka K, Yamanishi K, et al. Interleukin-18 and its receptor are expressed in gonadotropin-releasing hormone neurons of mouse and rat forebrain. Neurosci Lett. 2017;650:33-37 pubmed publisher

product information

master code :

AF856

SKU :

AF856

product name :

Mouse IL-18 R alpha /IL-1 R5 Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse IL-18 R alpha /IL-1 R5 Antibody from R&D Systems is a goat polyclonal antibody to IL-18R alpha/IL-1 R5. This antibody reacts with mouse. The Mouse IL-18 R alpha /IL-1 R5 Antibody has been validated for the following applications: Flow Cytometry,Neutralization,Immunohistochemistry,Immunohistochemistry-Frozen,In vivo assay,Western Blot,CyTOF-ready.

target :

IL-18 R alpha/IL-1 R5

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse IL-18 R alpha /IL-1 R5, Ser19-Gly326, Accession # Q61098

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Mouse

specificity :

Detects mouse IL-18 R alpha in direct ELISAs and Western blots. In direct ELISAs, approximately 25% cross-reactivity with recombinant human IL-18 R is observed.

gene symbol :

Il18rap

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

IFN-? Secretion Induced by IL-18/IL-1F4 and Neutralization by Mouse IL-18 Ra/IL-1 R5 Antibody.

accessionNumbers :

Q61098

applications :

Flow Cytometry,Neutralization,Immunohistochemistry,Immunohistochemistry-Frozen,In vivo assay,Western Blot,CyTOF-ready

USD :

459 USD

alt names :

CD218a, CD218a;CDw218a;IL18R1;IL18RA;IL-18Ralpha;IL-18R-alpha;IL18Ralpha2;IL1RRP;IL-1Rrp;Interleukin-18 receptor 1, IL-1 R5, IL-1 Rrp, IL-18 R1, IL18R alpha, IL18R1, IL-18Ra

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage