product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse/Rat PTEN Antibody
catalog :
AF847
quantity :
100 ug (also 25 ug)
price :
409 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry
more info or order :
citations: 13
Reference
Ren X, Yao B, Zhou X, Nie P, Xu S, Wang M, et al. Caulerpin alleviates cyclophosphamide-induced ovarian toxicity by modulating macrophage-associated granulosa cell senescence during breast cancer chemotherapy. Int Immunopharmacol. 2024;143:113513 pubmed publisher
Park J, Kim C, Choi J, Jeong H, Moon Y, Kang H, et al. MicroRNA-21a-5p inhibition alleviates systemic sclerosis by targeting STAT3 signaling. J Transl Med. 2024;22:323 pubmed publisher
Meah A, Vedarethinam V, Bronstein R, Gujarati N, Jain T, Mallipattu S, et al. Single-Cell Spatial MIST for Versatile, Scalable Detection of Protein Markers. Biosensors (Basel). 2023;13: pubmed publisher
Tarawneh N, Hamadneh L, Abu Irmaileh B, Shraideh Z, Bustanji Y, Abdalla S. Berberine Inhibited Growth and Migration of Human Colon Cancer Cell Lines by Increasing Phosphatase and Tensin and Inhibiting Aquaporins 1, 3 and 5 Expressions. Molecules. 2023;28: pubmed publisher
Al Rawashde F, Al Wajeeh A, Vishkaei M, Saad H, Johan M, Taib W, et al. Thymoquinone Inhibits JAK/STAT and PI3K/Akt/ mTOR Signaling Pathways in MV4-11 and K562 Myeloid Leukemia Cells. Pharmaceuticals (Basel). 2022;15: pubmed publisher
Park S, Uchida T, Tilson S, Hu Z, Ma C, Leek M, et al. A dual conditional CRISPR-Cas9 system to activate gene editing and reduce off-target effects in human stem cells. Mol Ther Nucleic Acids. 2022;28:656-669 pubmed publisher
Mortoglou M, Manić L, Buha Djordjevic A, Bulat Z, Đorđević V, Manis K, et al. Nickel's Role in Pancreatic Ductal Adenocarcinoma: Potential Involvement of microRNAs. Toxics. 2022;10: pubmed publisher
Mortoglou M, Buha Djordjevic A, Djordjevic V, Collins H, York L, Mani K, et al. Role of microRNAs in response to cadmium chloride in pancreatic ductal adenocarcinoma. Arch Toxicol. 2022;96:467-485 pubmed publisher
Ganguly P, Madonsela L, Chao J, Loewen C, O Connor T, Verheyen E, et al. A scalable Drosophila assay for clinical interpretation of human PTEN variants in suppression of PI3K/AKT induced cellular proliferation. PLoS Genet. 2021;17:e1009774 pubmed publisher
Blanchard T, Czinn S, Banerjee V, Sharda N, Bafford A, Mubariz F, et al. Identification of Cross Talk between FoxM1 and RASSF1A as a Therapeutic Target of Colon Cancer. Cancers (Basel). 2019;11: pubmed publisher
Tellios N, Belrose J, Tokarewicz A, Hutnik C, Liu H, Leask A, et al. TGF-? induces phosphorylation of phosphatase and tensin homolog: implications for fibrosis of the trabecular meshwork tissue in glaucoma. Sci Rep. 2017;7:812 pubmed publisher
Bianchini G, Kiermaier A, Bianchi G, Im Y, Pienkowski T, Liu M, et al. Biomarker analysis of the NeoSphere study: pertuzumab, trastuzumab, and docetaxel versus trastuzumab plus docetaxel, pertuzumab plus trastuzumab, or pertuzumab plus docetaxel for the neoadjuvant treatment of HER2-positive breast cancer. Breast Cancer Res. 2017;19:16 pubmed publisher
Fletcher C, Godfrey J, Shibakawa A, Bushell M, Bevan C. A novel role for GSK3? as a modulator of Drosha microprocessor activity and MicroRNA biogenesis. Nucleic Acids Res. 2016;: pubmed
product information
master code :
AF847
SKU :
AF847
product name :
Human/Mouse/Rat PTEN Antibody
unit size :
100 ug (also 25 ug)
description :
The Human/Mouse/Rat PTEN Antibody from R&D Systems is a rabbit polyclonal antibody to PTEN. This antibody reacts with human,insect - drosophila,mouse,rat. The Human/Mouse/Rat PTEN Antibody has been validated for the following applications: Western Blot,Immunohistochemistry,ELISA Development,Simple Western,Intracellular Staining by Flow Cytometry,CyTOF-ready,Knockout Validated.
target :
PTEN
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Rabbit
immunogen :
Human PTEN synthetic peptide, Ser385-Val403, Accession # P60484
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Insect - Drosophila,Mouse,Rat
specificity :
Detects human, mouse, and rat PTEN in Western blots.
gene symbol :
PTEN
Antibody validation :
Knockout/Knockdown
top caption :
Detection of Human/Mouse/Rat PTEN antibody by Western Blot.
accessionNumbers :
P60484
applications :
Western Blot,Immunohistochemistry,ELISA Development,Simple Western,Intracellular Staining by Flow Cytometry,CyTOF-ready,Knockout Validated
USD :
409 USD
alt names :
BZS, EC 3.1.3.16,10q23del, EC 3.1.3.48, EC 3.1.3.67, GLM2, MMAC1, MMAC1 phosphatase and tensin homolog deleted on chromosome 10, MMAC1MGC11227, Mutated in multiple advanced cancers 1, phosphatase and tensin homologDEC, phosphatidylinositol-34,5-trisphosphate 3-phosphatase and dual-specificityprotein phosphatase PTEN, PTEN1, TEP1MHAM
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.