Human/Mouse/Rat XIAP Antibody | R&D Systems AF8221 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse/Rat XIAP Antibody

catalog :

AF8221

quantity :

100 ug (also 25 ug)

price :

499 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 13

Published Application/Species/Sample/Dilution	Reference
western blot; human; fig 3	Lin K, Cheng S, Tsai S, Tsai J, Lin C, Cheung C. Delivery of a survivin promoter-driven antisense survivin-expressing plasmid DNA as a cancer therapeutic: a proof-of-concept study. Onco Targets Ther. 2016;9:2601-13 pubmed publisher
	Mu xf1 oz Galdeano T, Reigada D, Soto A, Barreda Manso M, Ru xed z Amezcua P, Nieto D xed az M, et al. Identification of a New Role of miR-199a-5p as Factor Implied in Neuronal Damage: Decreasing the Expression of Its Target X-Linked Anti-Apoptotic Protein (XIAP) After SCI. Int J Mol Sci. 2024;25: pubmed publisher
	Dum xe9 tier B, Zadoroznyj A, Berthelet J, Causse S, All xe8 gre J, Bourgeois P, et al. cIAP1/TRAF2 interplay promotes tumor growth through the activation of STAT3. Oncogene. 2023;42:198-208 pubmed publisher
	Sugisawa E, Kondo T, Kumagai Y, Kato H, Takayama Y, Isohashi K, et al. Nociceptor-derived Reg3γ prevents endotoxic death by targeting kynurenine pathway in microglia. Cell Rep. 2022;38:110462 pubmed publisher
	Ren Y, Wang X, Huang S, Xu Y, Weng G, Yu R. Alternol Sensitizes Renal Carcinoma Cells to TRAIL-Induced Apoptosis. Front Pharmacol. 2021;12:560903 pubmed publisher
	An Y, Jeon J, Sun L, Derakhshan A, Chen J, Carlson S, et al. Death agonist antibody against TRAILR2/DR5/TNFRSF10B enhances birinapant anti-tumor activity in HPV-positive head and neck squamous cell carcinomas. Sci Rep. 2021;11:6392 pubmed publisher
	Chang Y, Cheung C, Kuo Y. Tamoxifen Rechallenge Decreases Metastatic Potential but Increases Cell Viability and Clonogenicity in a Tamoxifen-Mediated Cytotoxicity-Resistant Subline of Human Breast MCF7 Cancer Cells. Front Cell Dev Biol. 2020;8:485 pubmed publisher
	Xiao R, An Y, Ye W, Derakhshan A, Cheng H, Yang X, et al. Dual Antagonist of cIAP/XIAP ASTX660 Sensitizes HPV- and HPV+ Head and Neck Cancers to TNFα, TRAIL, and Radiation Therapy. Clin Cancer Res. 2019;25:6463-6474 pubmed publisher
	Ward G, Lewis E, Ahn J, Johnson C, Lyons J, Martins V, et al. ASTX660, a Novel Non-peptidomimetic Antagonist of cIAP1/2 and XIAP, Potently Induces TNFα-Dependent Apoptosis in Cancer Cell Lines and Inhibits Tumor Growth. Mol Cancer Ther. 2018;17:1381-1391 pubmed publisher
	Fan R, Schrott L, Arnold T, Snelling S, Rao M, Graham D, et al. Chronic oxycodone induces axonal degeneration in rat brain. BMC Neurosci. 2018;19:15 pubmed publisher
	Liapis V, Zysk A, DeNichilo M, Zinonos I, Hay S, Panagopoulos V, et al. Anticancer efficacy of the hypoxia-activated prodrug evofosfamide is enhanced in combination with proapoptotic receptor agonists against osteosarcoma. Cancer Med. 2017;6:2164-2176 pubmed publisher
	Hayes H, Peterson B, Haldeman J, Newgard C, Hohmeier H, Stephens S. Delayed apoptosis allows islet β-cells to implement an autophagic mechanism to promote cell survival. PLoS ONE. 2017;12:e0172567 pubmed publisher
	Mędra A, Witkowska M, Majchrzak A, Cebula Obrzut B, Bonner M, Robak T, et al. Pro-Apoptotic Activity of New Honokiol/Triphenylmethane Analogues in B-Cell Lymphoid Malignancies. Molecules. 2016;21: pubmed publisher

product information

master code :

AF8221

SKU :

AF8221

product name :

Human/Mouse/Rat XIAP Antibody

unit size :

100 ug (also 25 ug)

description :

The Human/Mouse/Rat XIAP Antibody from R&D Systems is a goat polyclonal antibody to XIAP. This antibody reacts with human,mouse,rat. The Human/Mouse/Rat XIAP Antibody has been validated for the following applications: Immunohistochemistry,Western Blot,Immunocytochemistry,Flow Cytometry,Immunoprecipitation,Immunohistochemistry-Frozen,Simple Western,Knockout Validated.

target :

XIAP

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

E. coli -derived recombinant human XIAP, Met1-Ser497 (Ser162Cys), Accession # P98170

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Rat

specificity :

Detects human, mouse and rat XIAP in Western blots.

gene symbol :

XIAP

Antibody validation :

Knockout/Knockdown

top caption :

XIAP antibody in Human Lymphoma by Immunohistochemistry (IHC-P).

accessionNumbers :

P98170

applications :

Immunohistochemistry,Western Blot,Immunocytochemistry,Flow Cytometry,Immunoprecipitation,Immunohistochemistry-Frozen,Simple Western,Knockout Validated

USD :

499 USD

alt names :

API3X-linked inhibitor of apoptosis protein, apoptosis inhibitor 3, baculoviral IAP repeat-containing 4, baculoviral IAP repeat-containing protein 4, BIRC4, BIRC4XLP2, E3 ubiquitin-protein ligase XIAP, EC 6.3.2.-, hIAP3, hIAP-3, hILP, IAP3, IAP-3, IAP-like protein, ILP, ILP1, Inhibitor of apoptosis protein 3, MIHA, X-linked IAP, X-linked inhibitor of apoptosis

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage