Human/Mouse/Rat XIAP Antibody | R&D Systems AF8221 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse/Rat XIAP Antibody

catalog :

AF8221

quantity :

100 ug (also 25 ug)

price :

499 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 14

Published Application/Species/Sample/Dilution	Reference
western blot; human; fig 3	Lin K, Cheng S, Tsai S, Tsai J, Lin C, Cheung C. Delivery of a survivin promoter-driven antisense survivin-expressing plasmid DNA as a cancer therapeutic: a proof-of-concept study. Onco Targets Ther. 2016;9:2601-13 pubmed publisher
	Mu xf1 oz Galdeano T, Reigada D, Soto A, Barreda Manso M, Ru xed z Amezcua P, Nieto D xed az M, et al. Identification of a New Role of miR-199a-5p as Factor Implied in Neuronal Damage: Decreasing the Expression of Its Target X-Linked Anti-Apoptotic Protein (XIAP) After SCI. Int J Mol Sci. 2024;25: pubmed publisher
	Pedrosa P, Zhang Z, Nu xf1 ez Quintela V, Macías D, Ge J, Denholm M, et al. Inhibition of lung tumorigenesis by transient reprogramming in cancer cells. Cell Death Dis. 2024;15:857 pubmed publisher
	Dum xe9 tier B, Zadoroznyj A, Berthelet J, Causse S, All xe8 gre J, Bourgeois P, et al. cIAP1/TRAF2 interplay promotes tumor growth through the activation of STAT3. Oncogene. 2023;42:198-208 pubmed publisher
	Sugisawa E, Kondo T, Kumagai Y, Kato H, Takayama Y, Isohashi K, et al. Nociceptor-derived Reg3γ prevents endotoxic death by targeting kynurenine pathway in microglia. Cell Rep. 2022;38:110462 pubmed publisher
	Ren Y, Wang X, Huang S, Xu Y, Weng G, Yu R. Alternol Sensitizes Renal Carcinoma Cells to TRAIL-Induced Apoptosis. Front Pharmacol. 2021;12:560903 pubmed publisher
	An Y, Jeon J, Sun L, Derakhshan A, Chen J, Carlson S, et al. Death agonist antibody against TRAILR2/DR5/TNFRSF10B enhances birinapant anti-tumor activity in HPV-positive head and neck squamous cell carcinomas. Sci Rep. 2021;11:6392 pubmed publisher
	Chang Y, Cheung C, Kuo Y. Tamoxifen Rechallenge Decreases Metastatic Potential but Increases Cell Viability and Clonogenicity in a Tamoxifen-Mediated Cytotoxicity-Resistant Subline of Human Breast MCF7 Cancer Cells. Front Cell Dev Biol. 2020;8:485 pubmed publisher
	Xiao R, An Y, Ye W, Derakhshan A, Cheng H, Yang X, et al. Dual Antagonist of cIAP/XIAP ASTX660 Sensitizes HPV- and HPV+ Head and Neck Cancers to TNFα, TRAIL, and Radiation Therapy. Clin Cancer Res. 2019;25:6463-6474 pubmed publisher
	Ward G, Lewis E, Ahn J, Johnson C, Lyons J, Martins V, et al. ASTX660, a Novel Non-peptidomimetic Antagonist of cIAP1/2 and XIAP, Potently Induces TNFα-Dependent Apoptosis in Cancer Cell Lines and Inhibits Tumor Growth. Mol Cancer Ther. 2018;17:1381-1391 pubmed publisher
	Fan R, Schrott L, Arnold T, Snelling S, Rao M, Graham D, et al. Chronic oxycodone induces axonal degeneration in rat brain. BMC Neurosci. 2018;19:15 pubmed publisher
	Liapis V, Zysk A, DeNichilo M, Zinonos I, Hay S, Panagopoulos V, et al. Anticancer efficacy of the hypoxia-activated prodrug evofosfamide is enhanced in combination with proapoptotic receptor agonists against osteosarcoma. Cancer Med. 2017;6:2164-2176 pubmed publisher
	Hayes H, Peterson B, Haldeman J, Newgard C, Hohmeier H, Stephens S. Delayed apoptosis allows islet β-cells to implement an autophagic mechanism to promote cell survival. PLoS ONE. 2017;12:e0172567 pubmed publisher
	Mędra A, Witkowska M, Majchrzak A, Cebula Obrzut B, Bonner M, Robak T, et al. Pro-Apoptotic Activity of New Honokiol/Triphenylmethane Analogues in B-Cell Lymphoid Malignancies. Molecules. 2016;21: pubmed publisher

product information

brand :

R&D Systems

catalog number base :

AF8221

SKU :

AF8221

product name :

Human/Mouse/Rat XIAP Antibody

units size :

100 ug (also 25 ug)

description :

The Human/Mouse/Rat XIAP Antibody from R&D Systems is a goat polyclonal antibody to XIAP. This antibody reacts with human,mouse,rat. The Human/Mouse/Rat XIAP Antibody has been validated for the following applications: Flow Cytometry,Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Frozen,Simple Western,Immunocytochemistry,Knockout Validated.

target :

XIAP

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 Âµm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 Âµm filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

all_available conjugate :

Unconjugated

host :

Goat

immunogen :

E. coli -derived recombinant human XIAP, Met1-Ser497 (Ser162Cys), Accession # P98170

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Rat

specificity :

Detects human, mouse and rat XIAP in Western blots.

gene symbol :

XIAP

Antibody validation :

Knockout/Knockdown

top caption :

XIAP antibody in Human Lymphoma by Immunohistochemistry (IHC-P).

accessionNumbers :

P98170

applications :

Flow Cytometry,Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Frozen,Simple Western,Immunocytochemistry,Knockout Validated

USD :

499 USD

alt names :

API3X-linked inhibitor of apoptosis protein, apoptosis inhibitor 3, baculoviral IAP repeat-containing 4, baculoviral IAP repeat-containing protein 4, BIRC4, BIRC4XLP2, E3 ubiquitin-protein ligase XIAP, EC 6.3.2.-, hIAP3, hIAP-3, hILP, IAP3, IAP-3, IAP-like protein, ILP, ILP1, Inhibitor of apoptosis protein 3, MIHA, X-linked IAP, X-linked inhibitor of apoptosis

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 Â°C as supplied. 1 month, 2 to 8 Â°C under sterile conditions after reconstitution. 6 months, -20 to -70 Â°C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage