Human cIAP-2/HIAP-1 Antibody | R&D Systems AF8171 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human cIAP-2/HIAP-1 Antibody

catalog :

AF8171

quantity :

100 ug (also 25 ug)

price :

489 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry

more info or order :

R&D Systems product webpage

citations: 6

Reference
An Y, Jeon J, Sun L, Derakhshan A, Chen J, Carlson S, et al. Death agonist antibody against TRAILR2/DR5/TNFRSF10B enhances birinapant anti-tumor activity in HPV-positive head and neck squamous cell carcinomas. Sci Rep. 2021;11:6392 pubmed publisher
Xiao R, An Y, Ye W, Derakhshan A, Cheng H, Yang X, et al. Dual Antagonist of cIAP/XIAP ASTX660 Sensitizes HPV- and HPV+ Head and Neck Cancers to TNFα, TRAIL, and Radiation Therapy. Clin Cancer Res. 2019;25:6463-6474 pubmed publisher
Lee S, Lee J, Lee E, Park S, Kang D, Min C, et al. Absence of Cytosolic 2-Cys Prx Subtypes I and II Exacerbates TNF-α-Induced Apoptosis via Different Routes. Cell Rep. 2019;26:2194-2211.e6 pubmed publisher
Ward G, Lewis E, Ahn J, Johnson C, Lyons J, Martins V, et al. ASTX660, a Novel Non-peptidomimetic Antagonist of cIAP1/2 and XIAP, Potently Induces TNFα-Dependent Apoptosis in Cancer Cell Lines and Inhibits Tumor Growth. Mol Cancer Ther. 2018;17:1381-1391 pubmed publisher
Liapis V, Zysk A, DeNichilo M, Zinonos I, Hay S, Panagopoulos V, et al. Anticancer efficacy of the hypoxia-activated prodrug evofosfamide is enhanced in combination with proapoptotic receptor agonists against osteosarcoma. Cancer Med. 2017;6:2164-2176 pubmed publisher
Mędra A, Witkowska M, Majchrzak A, Cebula Obrzut B, Bonner M, Robak T, et al. Pro-Apoptotic Activity of New Honokiol/Triphenylmethane Analogues in B-Cell Lymphoid Malignancies. Molecules. 2016;21: pubmed publisher

product information

master code :

AF8171

SKU :

AF8171

product name :

Human cIAP-2/HIAP-1 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human cIAP-2/HIAP-1 Antibody from R&D Systems is a goat polyclonal antibody to cIAP-2/HIAP-1. This antibody reacts with human. The Human cIAP-2/HIAP-1 Antibody has been validated for the following applications: Western Blot,Flow Cytometry,Immunocytochemistry,Immunohistochemistry,Simple Western.

target :

cIAP-2/HIAP-1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

E. coli -derived recombinant human cIAP-2/HIAP-1, Asn2-Ser604, Accession # U45878

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human

specificity :

Detects human cIAP-2/HIAP-1 in Western blots. In Western blots, less than 1% cross-reactivity with cIAP-1 is observed.

gene symbol :

BIRC3

top caption :

cIAP-2/HIAP-1 antibody in Human Colon Tissue by Immunohistochemistry (IHC-P).

accessionNumbers :

U45878

applications :

Western Blot,Flow Cytometry,Immunocytochemistry,Immunohistochemistry,Simple Western

USD :

489 USD

alt names :

AIP1, API2, BIRC3, BIRC3 baculoviral IAP repeat containing 3, c-IAP2, CIAP2, HAIP1, HIAP1, HIAP-1, MALT2, MIHC, RNF49

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage