Human uPAR Antibody | R&D Systems AF807 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human uPAR Antibody

catalog :

AF807

quantity :

100 ug (also 25 ug)

price :

489 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, blocking or activating experiments

more info or order :

R&D Systems product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
blocking or activating experiments; human; loading ...; fig s4c immunoprecipitation; human; loading ...; fig s4a western blot; human; loading ...; fig 2a	Narayanaswamy P, Tkachuk S, Haller H, Dumler I, Kiyan Y. CHK1 and RAD51 activation after DNA damage is regulated via urokinase receptor/TLR4 signaling. Cell Death Dis. 2016;7:e2383 pubmed publisher
	Cheng Y, Hall T, Xu X, Yung I, Souza D, Zheng J, et al. Targeting uPA-uPAR interaction to improve intestinal epithelial barrier integrity in inflammatory bowel disease. EBioMedicine. 2022;75:103758 pubmed publisher
	Abraham A, Xu Y, Roem J, Greenberg J, Weidemann D, Sabbisetti V, et al. Variability in CKD Biomarker Studies: Soluble Urokinase Plasminogen Activator Receptor (suPAR) and Kidney Disease Progression in the Chronic Kidney Disease in Children (CKiD) Study. Kidney Med. 2021;3:712-721.e1 pubmed publisher
	Amor C, Feucht J, Leibold J, Ho Y, Zhu C, Alonso Curbelo D, et al. Senolytic CAR T cells reverse senescence-associated pathologies. Nature. 2020;583:127-132 pubmed publisher
	Harel E, Drake P, Barfield R, Lui I, Farr Jones S, van t Veer L, et al. Antibody-Drug Conjugates Targeting the Urokinase Receptor (uPAR) as a Possible Treatment of Aggressive Breast Cancer. Antibodies (Basel). 2019;8: pubmed publisher
	Annis M, Ouellet V, Rennhack J, L Esperance S, Rancourt C, Mes Masson A, et al. Integrin-uPAR signaling leads to FRA-1 phosphorylation and enhanced breast cancer invasion. Breast Cancer Res. 2018;20:9 pubmed publisher

product information

master code :

AF807

SKU :

AF807

product name :

Human uPAR Antibody

unit size :

100 ug (also 25 ug)

description :

The Human uPAR Antibody from R&D Systems is a goat polyclonal antibody to uPAR. This antibody reacts with human,mouse,rabbit. The Human uPAR Antibody has been validated for the following applications: Neutralization,Immunoprecipitation,Western Blot,Immunohistochemistry,Immunocytochemistry,Simple Western,Blockade of Receptor-ligand Interaction.

target :

uPAR

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant human uPAR, Leu23-Arg303, Accession # Q03405

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Rabbit

specificity :

Detects human uPAR in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant mouse uPAR is observed.

gene symbol :

PLAUR

top caption :

Detection of Human uPAR antibody by Western Blot.

accessionNumbers :

Q03405

applications :

Immunoprecipitation,Western Blot,Neutralization,Immunohistochemistry,Immunocytochemistry,Simple Western,Blockade of Receptor-ligand Interaction

USD :

489 USD

alt names :

CD87, CD87 antigen, Monocyte activation antigen Mo3, plasminogen activator, urokinase receptor, PLAUR, uPAR, U-PAR, UPARurokinase plasminogen activator surface receptor, u-plasminogen activator receptor form 2, URKRMO3

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage