Human RNF4 Antibody | R&D Systems AF7964-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human RNF4 Antibody

catalog :

AF7964-100

quantity :

100 ug (also 25 ug)

price :

479 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry

more info or order :

R&D Systems product webpage

citations: 7

Reference
Rodr xed guez P xe9 rez F, Natwick D, Schiff L, McSwiggen D, Heckert A, Huey M, et al. WRN inhibition leads to its chromatin-associated degradation via the PIAS4-RNF4-p97/VCP axis. Nat Commun. 2024;15:6059 pubmed publisher
Zhang H, Xiong Y, Sun Y, Park J, Su D, Feng X, et al. RAD54L2-mediated DNA damage avoidance pathway specifically preserves genome integrity in response to topoisomerase 2 poisons. Sci Adv. 2023;9:eadi6681 pubmed publisher
Krawic C, Luczak M, Valiente S, Zhitkovich A. Atypical genotoxicity of carcinogenic nickel(II): Linkage to dNTP biosynthesis, DNA-incorporated rNMPs, and impaired repair of TOP1-DNA crosslinks. J Biol Chem. 2023;299:105385 pubmed publisher
Chang Y, Lin K, Baxley R, Durrett W, Wang L, Stojkova O, et al. RNF4 and USP7 cooperate in ubiquitin-regulated steps of DNA replication. Open Biol. 2023;13:230068 pubmed publisher
Weickert P, Li H, G xf6 tz M, D xfc rauer S, Yaneva D, Zhao S, et al. SPRTN patient variants cause global-genome DNA-protein crosslink repair defects. Nat Commun. 2023;14:352 pubmed publisher
Young M, Chen Y, Wang S, Chang H, Yang W, Lee C, et al. Estradiol-mediated inhibition of Sp1 decreases miR-3194-5p expression to enhance CD44 expression during lung cancer progression. J Biomed Sci. 2022;29:3 pubmed publisher
Sha Z, Blyszcz T, González Prieto R, Vertegaal A, Goldberg A. Inhibiting ubiquitination causes an accumulation of SUMOylated newly synthesized nuclear proteins at PML bodies. J Biol Chem. 2019;294:15218-15234 pubmed publisher

product information

master code :

AF7964

SKU :

AF7964-100

product name :

Human RNF4 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human RNF4 Antibody from R&D Systems is a goat polyclonal antibody to RNF4. This antibody reacts with human,xenograft. The Human RNF4 Antibody has been validated for the following applications: Western Blot,Western Blots,Immunohistochemistry,Immunocytochemistry.

target :

RNF4

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

conjugate :

Unconjugated

host :

Goat

immunogen :

E.coli -derived recombinant human RNF4, Met1-Ile190, Accession # P78317

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Xenograft

specificity :

Detects human RNF4 in direct ELISAs and Western blots.

top caption :

Detection of Human RNF4 antibody by Western Blot.

accessionNumbers :

P78317

applications :

Western Blot,Western Blots,Immunohistochemistry,Immunocytochemistry

USD :

479 USD

alt names :

E3 ubiquitin ligase RNF4, EC 6.3.2.-, Protein SNURF, RES4-26, ring finger protein 4SNURFSLX5, SLX5, Small nuclear ring finger protein, SNURF

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage