Mouse IGF-II/IGF2 Antibody | R&D Systems AF792 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse IGF-II/IGF2 Antibody

catalog :

AF792

quantity :

100 ug (also 25 ug)

price :

499 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

mouse

application :

western blot, immunohistochemistry, neutralization, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 6

Reference
Sandovici I, Fernandez Twinn D, Campbell N, Cooper W, Sekita Y, Zvetkova I, et al. Overexpression of Igf2-derived Mir483 inhibits Igf1 expression and leads to developmental growth restriction and metabolic dysfunction in mice. Cell Rep. 2024;43:114750 pubmed publisher
Lee J, Garcia V, Nambiar S, Jiang H, Dai G. Activation of Proneuronal Transcription Factor Ascl1 in Maternal Liver Ensures a Healthy Pregnancy. Cell Mol Gastroenterol Hepatol. 2022;13:35-55 pubmed publisher
Wang Q, Tao C, Hannan A, Yoon S, Min X, Peregrin J, et al. Lacrimal gland budding requires PI3K-dependent suppression of EGF signaling. Sci Adv. 2021;7: pubmed publisher
Shen H, Gan P, Wang K, Darehzereshki A, Wang K, Kumar S, et al. Mononuclear diploid cardiomyocytes support neonatal mouse heart regeneration in response to paracrine IGF2 signaling. elife. 2020;9: pubmed publisher
Hughes J, Surakhy M, Can S, Ducker M, Davies N, SZELE F, et al. Maternal transmission of an Igf2r domain 11: IGF2 binding mutant allele (Igf2rI1565A) results in partial lethality, overgrowth and intestinal adenoma progression. Sci Rep. 2019;9:11388 pubmed publisher
Mussar K, Pardike S, Hohl T, Hardiman G, Cirulli V, Crisa L. A CCR2+ myeloid cell niche required for pancreatic β cell growth. JCI Insight. 2017;2: pubmed publisher

product information

master code :

AF792

SKU :

AF792

product name :

Mouse IGF-II/IGF2 Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse IGF-II/IGF2 Antibody from R&D Systems is a goat polyclonal antibody to IGF-II/IGF2. This antibody reacts with mouse,transgenic mouse. The Mouse IGF-II/IGF2 Antibody has been validated for the following applications: Immunohistochemistry,Western Blot,Neutralization,Immunohistochemistry-Frozen.

target :

IGF-II/IGF2

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

E. coli -derived recombinant mouse IGF-II/IGF2, Ala25-Glu91, Accession # P09535

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Mouse,Transgenic Mouse

specificity :

Detects mouse IGF-II/IGF2 in direct ELISAs and Western blots. In direct ELISAs, approximately 50% cross-reactivity with recombinant human IGF-II/IGF2 is observed.

gene symbol :

IGF2

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

IGF-II/IGF2 antibody in Mouse Embryo by Immunohistochemistry (IHC-Fr).

accessionNumbers :

P09535

applications :

Western Blot,Neutralization,Immunohistochemistry-Frozen,Immunohistochemistry

USD :

499 USD

alt names :

C11orf43, chromosome 11 open reading frame 43, FLJ22066, FLJ44734, GRDF, IGF2, IGF-2, IGFII, IGF-II, insulin-like growth factor 2 (somatomedin A), insulin-like growth factor II, insulin-like growth factor type 2, MSA, PEG2, PP9974, somatomedin-A

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage