Mouse IGF-I/IGF-1 Antibody | R&D Systems AF791 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse IGF-I/IGF-1 Antibody

catalog :

AF791

quantity :

100 ug (also 25 ug)

price :

519 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 19

Reference
Sandovici I, Fernandez Twinn D, Campbell N, Cooper W, Sekita Y, Zvetkova I, et al. Overexpression of Igf2-derived Mir483 inhibits Igf1 expression and leads to developmental growth restriction and metabolic dysfunction in mice. Cell Rep. 2024;43:114750 pubmed publisher
Ozaki Y, Ohashi K, Otaka N, Kawanishi H, Takikawa T, Fang L, et al. Myonectin protects against skeletal muscle dysfunction in male mice through activation of AMPK/PGC1α pathway. Nat Commun. 2023;14:4675 pubmed publisher
Miyagawa K, Tenshin H, Mulcrone P, Delgado Calle J, Subler M, Windle J, et al. Osteoclast-derived IGF1 induces RANKL production in osteocytes and contributes to pagetic lesion formation. JCI Insight. 2023;8: pubmed publisher
Wang J, Zhu Q, Cao D, Peng Q, Zhang X, Li C, et al. Bone marrow-derived IGF-1 orchestrates maintenance and regeneration of the adult skeleton. Proc Natl Acad Sci U S A. 2023;120:e2203779120 pubmed publisher
Liu Z, Shi H, Xu J, Yang Q, Ma Q, Mao X, et al. Single-cell transcriptome analyses reveal microglia types associated with proliferative retinopathy. JCI Insight. 2022;7: pubmed publisher
Fonteneau G, Redding A, Hoag Lee H, Sim E, Heinrich S, Gaida M, et al. Stress Granules determine the Development of Obesity-associated Pancreatic Cancer. Cancer Discov. 2022;: pubmed publisher
Martin Rodriguez O, Gauthier T, Bonnefoy F, Couturier M, Daoui A, Chagu xe9 C, et al. Pro-Resolving Factors Released by Macrophages After Efferocytosis Promote Mucosal Wound Healing in Inflammatory Bowel Disease. Front Immunol. 2021;12:754475 pubmed publisher
Ronzano R, Roux T, Thetiot M, Aigrot M, Richard L, Lejeune F, et al. Microglia-neuron interaction at nodes of Ranvier depends on neuronal activity through potassium release and contributes to remyelination. Nat Commun. 2021;12:5219 pubmed publisher
Wong N, Mohan J, Kopecky B, Guo S, Du L, Leid J, et al. Resident cardiac macrophages mediate adaptive myocardial remodeling. Immunity. 2021;54:2072-2088.e7 pubmed publisher
Kok H, Crowder C, Koo Min Chee L, Choi H, Lin N, Barton E. Muscle insulin-like growth factor-I modulates murine craniofacial bone growth. Eur Cell Mater. 2021;41:72-89 pubmed publisher
Wang Q, Tao C, Hannan A, Yoon S, Min X, Peregrin J, et al. Lacrimal gland budding requires PI3K-dependent suppression of EGF signaling. Sci Adv. 2021;7: pubmed publisher
Inoue M, Ono T, Kameo Y, Sasaki F, Ono T, Adachi T, et al. Forceful mastication activates osteocytes and builds a stout jawbone. Sci Rep. 2019;9:4404 pubmed publisher
Bellver Landete V, Bretheau F, Mailhot B, Vallières N, Lessard M, Janelle M, et al. Microglia are an essential component of the neuroprotective scar that forms after spinal cord injury. Nat Commun. 2019;10:518 pubmed publisher
Hillers L, D Amato J, Chamberlin T, Paderta G, Arendt L. Obesity-Activated Adipose-Derived Stromal Cells Promote Breast Cancer Growth and Invasion. Neoplasia. 2018;20:1161-1174 pubmed publisher
Park J, Kim I, Choi J, Lim H, Shin J, Kim Y, et al. AHNAK Loss in Mice Promotes Type II Pneumocyte Hyperplasia and Lung Tumor Development. Mol Cancer Res. 2018;16:1287-1298 pubmed publisher
Gao T, Bogdanova N, Ghauri S, Zhang G, Lin J, Sheikh K. Systemic IGF-1 gene delivery by rAAV9 improves spontaneous autoimmune peripheral polyneuropathy (SAPP). Sci Rep. 2018;8:5408 pubmed publisher
Zuo Z, Qi F, Yang J, Wang X, Wu Y, Wen Y, et al. Immunization with Bacillus Calmette-GuÃ©rin (BCG) alleviates neuroinflammation and cognitive deficits in APP/PS1 mice via the recruitment of inflammation-resolving monocytes to the brain. Neurobiol Dis. 2017;101:27-39 pubmed publisher
Kimura K, Terasaka T, Iwata N, Katsuyama T, Komatsubara M, Nagao R, et al. Combined Effects of Androgen and Growth Hormone on Osteoblast Marker Expression in Mouse C2C12 and MC3T3-E1 Cells Induced by Bone Morphogenetic Protein. J Clin Med. 2017;6: pubmed publisher
Zhao C, Zhang W, Zhao Y, Yang Y, Luo H, Ji G, et al. Endothelial Cords Promote Tumor Initial Growth prior to Vascular Function through a Paracrine Mechanism. Sci Rep. 2016;6:19404 pubmed publisher

product information

master code :

AF791

SKU :

AF791

product name :

Mouse IGF-I/IGF-1 Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse IGF-I/IGF-1 Antibody from R&D Systems is a goat polyclonal antibody to IGF-I/IGF-1. This antibody reacts with human,mouse,rat,transgenic mouse. The Mouse IGF-I/IGF-1 Antibody has been validated for the following applications: Immunohistochemistry,Neutralization,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,In vivo assay,Immunocytochemistry.

target :

IGF-I/IGF-1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

E. coli -derived recombinant mouse IGF-I/IGF-1, Gl33-Ala102, Accession # Q8CAR0

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Rat,Transgenic Mouse

specificity :

Detects mouse IGF-I/IGF-1 in direct ELISAs and Western blots. In direct ELISAs, approximately 15% cross-reactivity with recombinant human IGF-I/IGF-1 is observed, and less than 2% cross-reactivity with recombinant mouse IGF-II/IGF-2 is observed.

gene symbol :

IGF1

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Cell Proliferation Induced by IGF-I/IGF-1 and Neutralization by Mouse IGF-I/IGF-1 Antibody.

accessionNumbers :

Q8CAR0

applications :

Immunohistochemistry,Neutralization,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,In vivo assay,Immunocytochemistry

USD :

519 USD

alt names :

IBP1, IGF1, IGF-1, IGF1A, IGFI, IGF-I, IGF-IA, IGF-IB, insulin-like growth factor 1, insulin-like growth factor 1 (somatomedin C), insulin-like growth factor I, insulin-like growth factor IA, insulin-like growth factor IB, Mechano growth factor, MGF, Somatomedin A, Somatomedin C, Somatomedin-C

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage