Human/Mouse/Rat GDF-8/Myostatin Antibody | R&D Systems AF788 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse/Rat GDF-8/Myostatin Antibody

catalog :

AF788

quantity :

100 ug (also 25 ug)

price :

509 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 16

Reference
Yang H, Wei X, Gong J, DU X, Feng H, Su C, et al. The relationship between myodural bridge, atrophy and hyperplasia of the suboccipital musculature, and cerebrospinal fluid dynamics. Sci Rep. 2023;13:18882 pubmed publisher
Bermejo xc1 lvarez I, P xe9 rez Baos S, Gratal P, Medina J, Largo R, Herrero Beaumont G, et al. Effects of Tofacitinib on Muscle Remodeling in Experimental Rheumatoid Sarcopenia. Int J Mol Sci. 2023;24: pubmed publisher
Guan H, Yonemitsu I, Ikeda Y, Ono T. Reversible Effects of Functional Mandibular Lateral Shift on Masticatory Muscles in Growing Rats. Biomedicines. 2023;11: pubmed publisher
Maeta K, Farea M, Nishio H, Matsuo M. A novel splice variant of the human MSTN gene encodes a myostatin-specific myostatin inhibitor. J Cachexia Sarcopenia Muscle. 2023;14:2289-2300 pubmed publisher
Li F, Luo T, Rong H, Lu L, Zhang L, Zheng C, et al. Maternal rodent exposure to di-(2-ethylhexyl) phthalate decreases muscle mass in the offspring by increasing myostatin. J Cachexia Sarcopenia Muscle. 2022;13:2740-2751 pubmed publisher
Li C, Yue C, Liu Z, Gong J, Wei X, Yang H, et al. The relationship between myodural bridges, hyperplasia of the suboccipital musculature, and intracranial pressure. PLoS ONE. 2022;17:e0273193 pubmed publisher
Li H, Kuang J, Liu G, Wu W, Yin X, Li H, et al. Myostain is involved in ginsenoside Rb1-mediated anti-obesity. Pharm Biol. 2022;60:1106-1115 pubmed publisher
Muramatsu H, Kuramochi T, Katada H, Ueyama A, Ruike Y, Ohmine K, et al. Novel myostatin-specific antibody enhances muscle strength in muscle disease models. Sci Rep. 2021;11:2160 pubmed publisher
Pötsch M, Ishida J, Palus S, Tschirner A, von Haehling S, Doehner W, et al. MT-102 prevents tissue wasting and improves survival in a rat model of severe cancer cachexia. J Cachexia Sarcopenia Muscle. 2020;11:594-605 pubmed publisher
Jin Q, Qiao C, Li J, Xiao B, Li J, Xiao X. A GDF11/myostatin inhibitor, GDF11 propeptide-Fc, increases skeletal muscle mass and improves muscle strength in dystrophic mdx mice. Skelet Muscle. 2019;9:16 pubmed publisher
Kim K, Kuang S, Song Q, Gavin T, Roseguini B. Impact of heat therapy on recovery after eccentric exercise in humans. J Appl Physiol (1985). 2019;126:965-976 pubmed publisher
Wallner C, Jaurich H, Wagner J, Becerikli M, Harati K, Dadras M, et al. Inhibition of GDF8 (Myostatin) accelerates bone regeneration in diabetes mellitus type 2. Sci Rep. 2017;7:9878 pubmed publisher
Little R, Prieto Potin I, Pérez Baos S, Villalvilla A, Gratal P, Cicuttini F, et al. Compensatory anabolic signaling in the sarcopenia of experimental chronic arthritis. Sci Rep. 2017;7:6311 pubmed publisher
Ishida J, Konishi M, Saitoh M, Anker M, Anker S, Springer J. Myostatin signaling is up-regulated in female patients with advanced heart failure. Int J Cardiol. 2017;238:37-42 pubmed publisher
Miroshnychenko O, Chang W, Dragoo J. The Use of Platelet-Rich and Platelet-Poor Plasma to Enhance Differentiation of Skeletal Myoblasts: Implications for the Use of Autologous Blood Products for Muscle Regeneration. Am J Sports Med. 2017;45:945-953 pubmed publisher
Rebo J, Mehdipour M, Gathwala R, Causey K, Liu Y, Conboy M, et al. A single heterochronic blood exchange reveals rapid inhibition of multiple tissues by old blood. Nat Commun. 2016;7:13363 pubmed publisher

product information

master code :

AF788

SKU :

AF788

product name :

Human/Mouse/Rat GDF-8/Myostatin Antibody

unit size :

100 ug (also 25 ug)

description :

The Human/Mouse/Rat GDF-8/Myostatin Antibody from R&D Systems is a goat polyclonal antibody to GDF-8/Myostatin. This antibody reacts with human,mouse,rabbit,rat. The Human/Mouse/Rat GDF-8/Myostatin Antibody has been validated for the following applications: Western Blot,Immunohistochemistry,In vivo assay,Neutralization,Immunohistochemistry-Frozen,Immunocytochemistry.

target :

GDF-8/Myostatin

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

E. coli -derived recombinant mouse GDF-8/Myostatin, Asp268-Ser376, Accession # O08689

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Rabbit,Rat

specificity :

Detects human, mouse, and rat GDF-8/Myostatin in direct ELISAs and Western blots.

gene symbol :

MSTN

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Detection of Recombinant Human, Mouse, and Rat GDF-8/Myostatin antibody by Western Blot.

accessionNumbers :

O08689

applications :

In vivo assay,Western Blot,Neutralization,Immunohistochemistry,Immunohistochemistry-Frozen,Immunocytochemistry

USD :

509 USD

alt names :

GDF8, GDF-8, GDF8growth differentiation factor 8, growth/differentiation factor 8, MSLHP, MSTN, Myostatin

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage