Mouse IL-1 RI Antibody | R&D Systems AF771 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse IL-1 RI Antibody

catalog :

AF771

quantity :

100 ug (also 25 ug)

price :

519 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 17

Reference
Kidder E, Pea M, Cheng S, Koppada S, Visvanathan S, Henderson Q, et al. The interleukin-1 receptor type-1 in disturbed flow-induced endothelial mesenchymal activation. Front Cardiovasc Med. 2023;10:1190460 pubmed publisher
Yamamoto T, Kase S, Shinkai A, Murata M, Kikuchi K, Wu D, et al. Phosphorylation of αB-Crystallin Involves Interleukin-1β-Mediated Intracellular Retention in Retinal Müller Cells: A New Mechanism Underlying Fibrovascular Membrane Formation. Invest Ophthalmol Vis Sci. 2023;64:20 pubmed publisher
Edamakanti C, Mohan V, Opal P. Reactive Bergmann glia play a central role in spinocerebellar ataxia inflammation via the JNK pathway. J Neuroinflammation. 2023;20:126 pubmed publisher
Varodayan F, Pahng A, Davis T, Gandhi P, Bajo M, Steinman M, et al. Chronic ethanol induces a pro-inflammatory switch in interleukin-1β regulation of GABAergic signaling in the medial prefrontal cortex of male mice. Brain Behav Immun. 2023;110:125-139 pubmed publisher
Mittli D, Tukacs V, Ravasz L, Cs x151 sz x, Kozma T, Kardos J, et al. LPS-induced acute neuroinflammation, involving interleukin-1 beta signaling, leads to proteomic, cellular, and network-level changes in the prefrontal cortex of mice. Brain Behav Immun Health. 2023;28:100594 pubmed publisher
Villatoro A, Cuminetti V, Bernal A, Torroja C, Coss xed o I, Bengur xed a A, et al. Endogenous IL-1 receptor antagonist restricts healthy and malignant myeloproliferation. Nat Commun. 2023;14:12 pubmed publisher
Rahman M, Yang Y, Le B, Dutta A, Posyniak J, Faughnan P, et al. Interleukin-1 contributes to clonal expansion and progression of bone marrow fibrosis in JAK2V617F-induced myeloproliferative neoplasm. Nat Commun. 2022;13:5347 pubmed publisher
Furrer R, Jauch A, Nageswara Rao T, Dilbaz S, Rhein P, Steurer S, et al. Remodeling of metabolism and inflammation by exercise ameliorates tumor-associated anemia. Sci Adv. 2021;7:eabi4852 pubmed publisher
Dani N, Herbst R, McCabe C, Green G, Kaiser K, Head J, et al. A cellular and spatial map of the choroid plexus across brain ventricles and ages. Cell. 2021;184:3056-3074.e21 pubmed publisher
Shimada A, Hasegawa Ishii S. Increased cytokine expression in the choroid plexus stroma and epithelium in response to endotoxin-induced systemic inflammation in mice. Toxicol Rep. 2021;8:520-528 pubmed publisher
Melchor S, Hatter J, Castillo É, Saunders C, Byrnes K, Sanders I, et al. T. gondii infection induces IL-1R dependent chronic cachexia and perivascular fibrosis in the liver and skeletal muscle. Sci Rep. 2020;10:15724 pubmed publisher
Liu X, Nemeth D, McKim D, Zhu L, DiSabato D, Berdysz O, et al. Cell-Type-Specific Interleukin 1 Receptor 1 Signaling in the Brain Regulates Distinct Neuroimmune Activities. Immunity. 2019;50:317-333.e6 pubmed publisher
Wong R, Lénárt N, Hill L, Toms L, Coutts G, Martinecz B, et al. Interleukin-1 mediates ischaemic brain injury via distinct actions on endothelial cells and cholinergic neurons. Brain Behav Immun. 2019;76:126-138 pubmed publisher
Biffi G, Oni T, Spielman B, Hao Y, Elyada E, Park Y, et al. IL1-Induced JAK/STAT Signaling Is Antagonized by TGFβ to Shape CAF Heterogeneity in Pancreatic Ductal Adenocarcinoma. Cancer Discov. 2019;9:282-301 pubmed publisher
Hsiao H, Fernandez R, Tanaka S, Li W, Spahn J, Chiu S, et al. Spleen-derived classical monocytes mediate lung ischemia-reperfusion injury through IL-1β. J Clin Invest. 2018;128:2833-2847 pubmed publisher
Coutu D, Kokkaliaris K, Kunz L, Schroeder T. Multicolor quantitative confocal imaging cytometry. Nat Methods. 2018;15:39-46 pubmed publisher
Liu B, Su M, Tang S, Zhou X, Zhan H, Yang F, et al. Spinal astrocytic activation contributes to mechanical allodynia in a rat model of cyclophosphamide-induced cystitis. Mol Pain. 2016;12: pubmed

product information

brand :

R&D Systems

master code :

AF771

SKU :

AF771

product name :

Mouse IL-1 RI Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Mouse IL-1 RI Antibody from R&D Systems is a goat polyclonal antibody to IL-1 RI. This antibody reacts with mouse,primate - macaca fuscata (japanese macaque),rat,transgenic mouse. The Mouse IL-1 RI Antibody has been validated for the following applications: Immunohistochemistry,ELISA Development,Immunoprecipitation,Western Blot,Neutralization,Immunohistochemistry-Frozen,In vivo assay,Immunocytochemistry.

target :

IL-1 RI

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Western Blot 0.1 ug/mL, Immunohistochemistry 1-15 ug/mL, Neutralization 0.2-1.0 ug/mL

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse IL-1 RI, Leu20-Lys338, Accession # P13504

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Mouse,Primate - Macaca fuscata (Japanese Macaque),Rat,Transgenic Mouse

specificity :

Detects mouse IL-1 RI in direct ELISAs and Western blots. In direct ELISAs, less than 15% cross-reactivity with recombinant mouse IL-18 R and recombinant human IL-1 RI is observed.

gene symbol :

IL1R1

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

IL-1 RI antibody in Mouse Skin by Immunohistochemistry (IHC-Fr).

accessionNumbers :

P13504

applications :

ELISA Development,Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Frozen,In vivo assay,Neutralization,Immunocytochemistry

USD :

519 USD

alt names :

CD121 antigen-like family member A, CD121a, CD121a antigen, IL1R, IL1R1, IL1RI, IL-1RI, IL1RT1, IL-1RT1, IL-1RT-1, Interleukin 1 Receptor 1, interleukin 1 receptor, type I, interleukin receptor 1, interleukin-1 receptor type 1, p80

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage