Mouse ALK-1 Antibody | R&D Systems AF770 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse ALK-1 Antibody

catalog :

AF770

quantity :

100 ug (also 25 ug)

price :

489 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, neutralization, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 5

Reference
Zhang X, Jacobs K, Raygor K, Li S, Li J, Wang R. Arterial endothelial deletion of hereditary hemorrhagic telangiectasia 2/ Alk1 causes epistaxis and cerebral microhemorrhage with aberrant arteries and defective smooth muscle coverage. bioRxiv. 2024;: pubmed publisher
Morita M, Yoneda A, Tokunoh N, Masaki T, Shirakura K, Kinoshita M, et al. Upregulation of Robo4 expression by SMAD signaling suppresses vascular permeability and mortality in endotoxemia and COVID-19 models. Proc Natl Acad Sci U S A. 2023;120:e2213317120 pubmed publisher
Viallard C, Audiger C, Popovic N, Akla N, Lanthier K, Legault Navarrete I, et al. BMP9 signaling promotes the normalization of tumor blood vessels. Oncogene. 2020;39:2996-3014 pubmed publisher
Ola R, Dubrac A, Han J, Zhang F, Fang J, Larrivee B, et al. PI3 kinase inhibition improves vascular malformations in mouse models of hereditary haemorrhagic telangiectasia. Nat Commun. 2016;7:13650 pubmed publisher
Ntumba K, Akla N, Oh S, Eichmann A, Larrivee B. BMP9/ALK1 inhibits neovascularization in mouse models of age-related macular degeneration. Oncotarget. 2016;7:55957-55969 pubmed publisher

product information

master code :

AF770

SKU :

AF770

product name :

Mouse ALK-1 Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse ALK-1 Antibody from R&D Systems is a goat polyclonal antibody to ALK-1. This antibody reacts with human,mouse,transgenic mouse. The Mouse ALK-1 Antibody has been validated for the following applications: Immunocytochemistry,Immunohistochemistry,Neutralization,Immunohistochemistry-Frozen,Western Blot,ELISA Capture (Matched Antibody Pair).

target :

ALK-1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse ALK-1, Asp23-Pro119, Accession # Q61288

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Transgenic Mouse

specificity :

Detects mouse ALK-1 in ELISAs and Western blots. In sandwich immunoassays, less than 5% cross-reactivity with recombinant human ALK-1 is observed.

gene symbol :

ACVRL1

accessionNumbers :

Q61288

applications :

Immunocytochemistry,Immunohistochemistry,Neutralization,Immunohistochemistry-Frozen,Western Blot,ELISA Capture (Matched Antibody Pair)

USD :

489 USD

alt names :

activin A receptor type II-like 1, activin A receptor, type II-like kinase 1, Activin receptor-like kinase 1, ACVRL1, ACVRLK1ORW2, ALK1, ALK-1, ALK1TGF-B superfamily receptor type I, EC 2.7.11, HHT, HHT2EC 2.7.11.30, serine/threonine-protein kinase receptor R3, SKR3, TSR-I

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage