Mouse P-Cadherin Antibody | R&D Systems AF761 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse P-Cadherin Antibody

catalog :

AF761

quantity :

100 ug (also 25 ug)

price :

509 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, western blot knockout validation

more info or order :

R&D Systems product webpage

citations: 26

Published Application/Species/Sample/Dilution	Reference
western blot knockout validation; mouse; loading ...; fig s1	Naydenov N, Lechuga S, Zalavadia A, Mukherjee P, Gordon I, Skvasik D, et al. P-Cadherin Regulates Intestinal Epithelial Cell Migration and Mucosal Repair, but Is Dispensable for Colitis Associated Colon Cancer. Cells. 2022;11: pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 6a immunocytochemistry; mouse; 1:200; loading ...; fig 6h western blot; mouse; 1:1000; loading ...; fig 6b, 6e	Shao C, Lou P, Liu R, Bi X, Li G, Yang X, et al. Hormone-Responsive BMP Signaling Expands Myoepithelial Cell Lineages and Prevents Alveolar Precocity in Mammary Gland. Front Cell Dev Biol. 2021;9:691050 pubmed publisher
	Xiong L, Zhevlakova I, West X, Gao D, Murtazina R, Horak A, et al. TLR2 Regulates Hair Follicle Cycle and Regeneration via BMP Signaling. bioRxiv. 2023;: pubmed publisher
	Wang X, Ramos R, Phan A, Yamaga K, Flesher J, Jiang S, et al. Signalling by senescent melanocytes hyperactivates hair growth. Nature. 2023;618:808-817 pubmed publisher
	Stewart K, Gonzales K, Yuan S, Tierney M, Bonny A, Yang Y, et al. Stem cells tightly regulate dead cell clearance to maintain tissue fitness. bioRxiv. 2023;: pubmed publisher
	Dhingra A, Tobias J, Philp N, Boesze Battaglia K. Transcriptomic Changes Predict Metabolic Alterations in LC3 Associated Phagocytosis in Aged Mice. Int J Mol Sci. 2023;24: pubmed publisher
	An S, Kim H, Kim S, Van S, Kim H, Lee J, et al. Keratin-mediated hair growth and its underlying biological mechanism. Commun Biol. 2022;5:1270 pubmed publisher
	Liang X, Weberling A, Hii C, Zernicka Goetz M, Buckley C. E-cadherin mediates apical membrane initiation site localisation during de novo polarisation of epithelial cavities. EMBO J. 2022;41:e111021 pubmed publisher
	Ng K, Lim J, Tan Y, Quek D, Lim Z, Pantelireis N, et al. Sox2 in the dermal papilla regulates hair follicle pigmentation. Cell Rep. 2022;40:111100 pubmed publisher
	Naeem Z, Zukunft S, G xfc nther S, Liebner S, Weigert A, Hammock B, et al. Role of the soluble epoxide hydrolase in the hair follicle stem cell homeostasis and hair growth. Pflugers Arch. 2022;474:1021-1035 pubmed publisher
	Qu R, Gupta K, Dong D, Jiang Y, Landa B, Saez C, et al. Decomposing a deterministic path to mesenchymal niche formation by two intersecting morphogen gradients. Dev Cell. 2022;57:1053-1067.e5 pubmed publisher
	Choi S, Zhang B, Ma S, Gonzalez Celeiro M, Stein D, Jin X, et al. Corticosterone inhibits GAS6 to govern hair follicle stem-cell quiescence. Nature. 2021;592:428-432 pubmed publisher
	Xi L, Carroll T, Matos I, Luo J, Polak L, Pasolli H, et al. m6A RNA methylation impacts fate choices during skin morphogenesis. elife. 2020;9: pubmed publisher
	Abbasi S, Sinha S, Labit E, Rosin N, Yoon G, Rahmani W, et al. Distinct Regulatory Programs Control the Latent Regenerative Potential of Dermal Fibroblasts during Wound Healing. Cell Stem Cell. 2020;27:396-412.e6 pubmed publisher
	Li G, Tang X, Zhang S, Jin M, Wang M, Deng Z, et al. SIRT7 activates quiescent hair follicle stem cells to ensure hair growth in mice. EMBO J. 2020;:e104365 pubmed publisher
	Matos I, Asare A, Levorse J, Ouspenskaia T, de la Cruz Racelis J, Schuhmacher L, et al. Progenitors oppositely polarize WNT activators and inhibitors to orchestrate tissue development. elife. 2020;9: pubmed publisher
	Ge M, Liu C, Li L, Lan M, Yu Y, Gu L, et al. miR-29a/b1 Inhibits Hair Follicle Stem Cell Lineage Progression by Spatiotemporally Suppressing WNT and BMP Signaling. Cell Rep. 2019;29:2489-2504.e4 pubmed publisher
	Laurin M, Gomez N, Levorse J, Sendoel A, Sribour M, Fuchs E. An RNAi screen unravels the complexities of Rho GTPase networks in skin morphogenesis. elife. 2019;8: pubmed publisher
	Yamada S, Lav R, Li J, Tucker A, Green J. Molar Bud-to-Cap Transition Is Proliferation Independent. J Dent Res. 2019;98:1253-1261 pubmed publisher
	Binder M, Chmielarz P, McKinnon P, Biggs L, Thesleff I, Balic A. Functionally Distinctive Ptch Receptors Establish Multimodal Hedgehog Signaling in the Tooth Epithelial Stem Cell Niche. Stem Cells. 2019;37:1238-1248 pubmed publisher
	Gupta K, Levinsohn J, LINDERMAN G, Chen D, Sun T, Dong D, et al. Single-Cell Analysis Reveals a Hair Follicle Dermal Niche Molecular Differentiation Trajectory that Begins Prior to Morphogenesis. Dev Cell. 2019;48:17-31.e6 pubmed publisher
	Yang X, Chung J, Rai U, Esumi N. Cadherins in the retinal pigment epithelium (RPE) revisited: P-cadherin is the highly dominant cadherin expressed in human and mouse RPE in vivo. PLoS ONE. 2018;13:e0191279 pubmed publisher
	Sanz Navarro M, Seidel K, Sun Z, Bertonnier Brouty L, Amendt B, Klein O, et al. Plasticity within the niche ensures the maintenance of a Sox2+ stem cell population in the mouse incisor. Development. 2018;145: pubmed publisher
	Brown S, Pineda C, Xin T, Boucher J, Suozzi K, Park S, et al. Correction of aberrant growth preserves tissue homeostasis. Nature. 2017;548:334-337 pubmed publisher
	Hoeck J, Biehs B, Kurtova A, Kljavin N, De Sousa E Melo F, Alicke B, et al. Stem cell plasticity enables hair regeneration following Lgr5+ cell loss. Nat Cell Biol. 2017;19:666-676 pubmed publisher
	Ge Y, Gomez N, Adam R, Nikolova M, Yang H, Verma A, et al. Stem Cell Lineage Infidelity Drives Wound Repair and Cancer. Cell. 2017;169:636-650.e14 pubmed publisher

product information

brand :

R&D Systems

master code :

AF761

SKU :

AF761

product name :

Mouse P-Cadherin Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Mouse P-Cadherin Antibody from R&D Systems is a goat polyclonal antibody to P-Cadherin. This antibody reacts with mouse,transgenic mouse. The Mouse P-Cadherin Antibody has been validated for the following applications: Immunohistochemistry,Immunohistochemistry-Frozen,Immunocytochemistry,Flow Cytometry,Western Blot,Simple Western,Adhesion Blockade,ELISA Capture (Matched Antibody Pair),CyTOF-ready.

target :

P-Cadherin

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Western Blot 0.5 ug/mL, Simple Western 25 ug/mL, Flow Cytometry 0.25 ug/10^6 cells, Immunohistochemistry 0.5-15 ug/mL, Adhesion Blockade, Immunocytochemistry 5-15 ug/mL, CyTOF-ready, ELISA Capture (Matched Antibody Pair) 0.2-0.8 ug/mL

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse P-Cadherin, Glu100-Gly647, Accession # Q8BSL6

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Mouse,Transgenic Mouse

specificity :

Detects P-Cadherin in ELISAs and Western blots. In sandwich immunoassays, less than 2% cross-reactivity with recombinant human (rh) P-Cadherin is observed and less than 0.3% cross-reactivity with recombinant mouse E-Cadherin, rhN-Cadherin, and rhCadherin-8 is observed.

gene symbol :

CDH3

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Detection of P-Cadherin antibody by Western Blot.

accessionNumbers :

Q8BSL6

applications :

Flow Cytometry,Western Blot,Simple Western,Adhesion Blockade,ELISA Capture (Matched Antibody Pair),CyTOF-ready,Immunohistochemistry,Immunohistochemistry-Frozen,Immunocytochemistry

USD :

509 USD

alt names :

CAD3, cadherin 3, P-cadherin (placental), cadherin 3, type 1, P-cadherin (placental), cadherin-3, CDH3, CDHP, CDHPcalcium-dependent adhesion protein, placental, HJMD, PCAD, PCadherin, PCADP-cadherin, Placental cadherin

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage