Human VEGF-C Antibody | R&D Systems AF752 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human VEGF-C Antibody

catalog :

AF752

quantity :

100 ug (also 25 ug)

price :

479 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, neutralization, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 13

Reference
Qi L, Li X, Zhang F, Zhu X, Zhao Q, Yang D, et al. VEGFR-3 signaling restrains the neuron-macrophage crosstalk during neurotropic viral infection. Cell Rep. 2023;42:112489 pubmed publisher
Korneeva N, Khalil M, Ghosh I, Fan R, Arnold T, De Benedetti A. SARS-CoV-2 viral protein Nsp2 stimulates translation under normal and hypoxic conditions. Virol J. 2023;20:55 pubmed publisher
Izumi A, Yamamoto K, Kawaguchi M, Yamashita F, Fukushima T, Kiwaki T, et al. Insufficiency of hepatocyte growth factor activator inhibitor-1 confers lymphatic invasion of tongue carcinoma cells. Cancer Sci. 2022;113:2179-2193 pubmed publisher
Dupont L, Joannes L, Morfoisse F, Blacher S, Monseur C, Deroanne C, et al. ADAMTS2 and ADAMTS14 can substitute for ADAMTS3 in adults for pro-VEGFC activation and lymphatic homeostasis. JCI Insight. 2022;7: pubmed publisher
Szőke D, Kovacs G, Kemecsei É, Bálint L, Szoták Ajtay K, Aradi P, et al. Nucleoside-modified VEGFC mRNA induces organ-specific lymphatic growth and reverses experimental lymphedema. Nat Commun. 2021;12:3460 pubmed publisher
Hwang I, Kim J, Ylaya K, Chung E, Kitano H, Perry C, et al. Tumor-associated macrophage, angiogenesis and lymphangiogenesis markers predict prognosis of non-small cell lung cancer patients. J Transl Med. 2020;18:443 pubmed publisher
Wang G, Muhl L, Padberg Y, Dupont L, Peterson Maduro J, Stehling M, et al. Specific fibroblast subpopulations and neuronal structures provide local sources of Vegfc-processing components during zebrafish lymphangiogenesis. Nat Commun. 2020;11:2724 pubmed publisher
Song E, Mao T, Dong H, Boisserand L, Antila S, Bosenberg M, et al. VEGF-C-driven lymphatic drainage enables immunosurveillance of brain tumours. Nature. 2020;577:689-694 pubmed publisher
Rudzinska M, Mikula M, Arczewska K, Gajda E, Sabalińska S, Stepien T, et al. Transcription Factor Prospero Homeobox 1 (PROX1) as a Potential Angiogenic Regulator of Follicular Thyroid Cancer Dissemination. Int J Mol Sci. 2019;20: pubmed publisher
Jha S, Rauniyar K, Chronowska E, Mattonet K, Maina E, Koistinen H, et al. KLK3/PSA and cathepsin D activate VEGF-C and VEGF-D. elife. 2019;8: pubmed publisher
Aström P, Juurikka K, Hadler Olsen E, Svineng G, Cervigne N, Coletta R, et al. The interplay of matrix metalloproteinase-8, transforming growth factor-?1 and vascular endothelial growth factor-C cooperatively contributes to the aggressiveness of oral tongue squamous cell carcinoma. Br J Cancer. 2017;117:1007-1016 pubmed publisher
Jha S, Rauniyar K, Karpanen T, Leppänen V, Brouillard P, Vikkula M, et al. Efficient activation of the lymphangiogenic growth factor VEGF-C requires the C-terminal domain of VEGF-C and the N-terminal domain of CCBE1. Sci Rep. 2017;7:4916 pubmed publisher
Kitano H, Chung J, Noh K, Lee Y, Kim T, Lee S, et al. Synaptonemal complex protein 3 is associated with lymphangiogenesis in non-small cell lung cancer patients with lymph node metastasis. J Transl Med. 2017;15:138 pubmed publisher

product information

master code :

AF752

SKU :

AF752

product name :

Human VEGF-C Antibody

unit size :

100 ug (also 25 ug)

description :

The Human VEGF-C Antibody from R&D Systems is a goat polyclonal antibody to VEGF-C. This antibody reacts with human,mouse,primate - chlorocebus aethiops (african green monkey). The Human VEGF-C Antibody has been validated for the following applications: Immunohistochemistry,Western Blot,Neutralization,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,ELISA.

target :

VEGF-C

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

E. coli -derived recombinant human VEGF-C

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Primate - Chlorocebus aethiops (African Green Monkey)

specificity :

Detects human VEGF-C in direct ELISAs and Western blots.

gene symbol :

VEGFC

top caption :

Detection of Human VEGF-C antibody by Western Blot.

applications :

Immunohistochemistry,Western Blot,Neutralization,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,ELISA

USD :

479 USD

alt names :

Flt4 ligand, Flt4-L, vascular endothelial growth factor C, Vascular endothelial growth factor-related protein, VEGFC, VEGF-C, VRPFLT4 ligand DHM

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage