Mouse CD74 Antibody | R&D Systems AF7478 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse CD74 Antibody

catalog :

AF7478

quantity :

100 ug (also 25 ug)

price :

489 USD

clonality :

polyclonal

host :

domestic sheep

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry

more info or order :

R&D Systems product webpage

citations: 6

Reference
Qiu Z, Khalife J, Ethiraj P, Jaafar C, Lin A, Holder K, et al. IRF8-mutant B cell lymphoma evades immunity through a CD74-dependent deregulation of antigen processing and presentation in MHCII complexes. Sci Adv. 2024;10:eadk2091 pubmed publisher
Gruel R, Bijnens B, Van den Daele J, Thys S, Willems R, Wuyts D, et al. S100A8-enriched microglia populate the brain of tau-seeded and accelerated aging mice. Aging Cell. 2024;23:e14120 pubmed publisher
Qiu Z, Khalife J, Lin A, Ethiraj P, Jaafar C, Chiou L, et al. IRF8-mutant B cell lymphoma evades immunity through a CD74-dependent deregulation of antigen processing and presentation in MHC CII complexes. bioRxiv. 2023;: pubmed publisher
Ebert S, Zang L, Ismail N, Otabil M, Fr xf6 hlich A, Egea V, et al. Tissue Inhibitor of Metalloproteinases-1 Interacts with CD74 to Promote AKT Signaling, Monocyte Recruitment Responses, and Vascular Smooth Muscle Cell Proliferation. Cells. 2023;12: pubmed publisher
Feng Z, Zhou J, Liu Y, Xia R, Li Q, Yan L, et al. Epithelium- and endothelium-derived exosomes regulate the alveolar macrophages by targeting RGS1 mediated calcium signaling-dependent immune response. Cell Death Differ. 2021;28:2238-2256 pubmed publisher
Farr L, Ghosh S, Jiang N, Watanabe K, Parlak M, Bucala R, et al. CD74 Signaling Links Inflammation to Intestinal Epithelial Cell Regeneration and Promotes Mucosal Healing. Cell Mol Gastroenterol Hepatol. 2020;10:101-112 pubmed publisher

product information

master code :

AF7478

SKU :

AF7478

product name :

Mouse CD74 Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse CD74 Antibody from R&D Systems is a sheep polyclonal antibody to CD74. This antibody reacts with human,mouse. The Mouse CD74 Antibody has been validated for the following applications: Immunohistochemistry,Westen Blot,ELISA Control,Western Blot,Immunocytochemistry,Simple Western.

target :

CD74

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Sheep

immunogen :

Chinese hamster ovary cell line CHO-derived recombinant mouse CD74, Gln56-Leu215, Accession # NP_034675

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse

specificity :

Detects mouse CD74 in direct ELISAs and Western blots. In direct ELISAs, approximately 50% cross-reactivity with recombinant human CD74 is observed.

gene symbol :

CD74

top caption :

Detection of Mouse CD74 antibody by Western Blot.

accessionNumbers :

NP_034675

applications :

Immunohistochemistry,Westen Blot,ELISA Control,Western Blot,Immunocytochemistry,Simple Western

USD :

489 USD

alt names :

CD74, CD74 antigen, CD74 antigen (invariant polypeptide of major histocompatibility complex, classII antigen-associated), CD74 molecule, major histocompatibility complex, class II invariant chain, CLIP, DHLAG, DHLAGgamma chain of class II antigens, HLA class II histocompatibility antigen gamma chain, HLADG, HLA-DR antigens-associated invariant chain, HLA-DR-gamma, Ia antigen-associated invariant chain, Ia-associated invariant chain, Ia-GAMMA, Ii, INVG34, MHC HLA-DR gamma chain, p33

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage