product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human PITX2 Antibody
catalog :
AF7388
quantity :
100 ug (also 25 ug)
price :
499 USD
clonality :
polyclonal
host :
domestic sheep
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 8
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig s3
Sweat M, Sweat Y, Yu W, Su D, Leonard R, Eliason S, et al. The miR-200 family is required for ectodermal organ development through the regulation of the epithelial stem cell niche. Stem Cells. 2021;39:761-775 pubmed publisher
Su D, Eliason S, Sun Z, Shao F, Amendt B. Wolf-Hirschhorn syndrome candidate 1 (Whsc1) methyltransferase signals via a Pitx2-miR-23/24 axis to effect tooth development. J Biol Chem. 2023;299:105324 pubmed publisher
Brink K, Henríquez J, Grieco T, Martin Del Campo J, Fu K, Richman J. Tooth Removal in the Leopard Gecko and the de novo Formation of Replacement Teeth. Front Physiol. 2021;12:576816 pubmed publisher
Zhang Y, Xu M, Shi X, Sun X, Mu W, Wu H, et al. Cascade diversification directs generation of neuronal diversity in the hypothalamus. Cell Stem Cell. 2021;28:1483-1499.e8 pubmed publisher
Gantner C, Cota Coronado A, Thompson L, Parish C. An Optimized Protocol for the Generation of Midbrain Dopamine Neurons under Defined Conditions. STAR Protoc. 2020;1:100065 pubmed publisher
Yu W, Sun Z, Sweat Y, Sweat M, Venugopalan S, Eliason S, et al. Pitx2-Sox2-Lef1 interactions specify progenitor oral/dental epithelial cell signaling centers. Development. 2020;147: pubmed publisher
Gantner C, De Luzy I, Kauhausen J, Moriarty N, Niclis J, Bye C, et al. Viral Delivery of GDNF Promotes Functional Integration of Human Stem Cell Grafts in Parkinson's Disease. Cell Stem Cell. 2020;26:511-526.e5 pubmed publisher
De Luzy I, Niclis J, Gantner C, Kauhausen J, Hunt C, Ermine C, et al. Isolation of LMX1a Ventral Midbrain Progenitors Improves the Safety and Predictability of Human Pluripotent Stem Cell-Derived Neural Transplants in Parkinsonian Disease. J Neurosci. 2019;39:9521-9531 pubmed publisher
product information
master code :
AF7388
SKU :
AF7388
product name :
Human PITX2 Antibody
unit size :
100 ug (also 25 ug)
description :
The Human PITX2 Antibody from R&D Systems is a sheep polyclonal antibody to PITX2. This antibody reacts with human,lizard - gecko,mouse,rat,transgenic mouse. The Human PITX2 Antibody has been validated for the following applications: Immunohistochemistry,Immunocytochemistry.
target :
PITX2
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Sheep
immunogen :
E. coli -derived recombinant human PITX2, Ala149-Val317, Accession # Q99697
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Lizard - Gecko,Mouse,Rat,Transgenic Mouse
specificity :
Detects human PITX2 in direct ELISAs. In direct ELISAs, less than 5% cross-reactivity with recombinant human PITX1 is observed.
gene symbol :
PITX2
top caption :
PITX2 antibody in Human Thyroid Cancer Tissue by Immunohistochemistry (IHC-P).
accessionNumbers :
Q99697
applications :
Immunohistochemistry,Immunocytochemistry
USD :
499 USD
alt names :
all1-responsive gene 1, ALL1-responsive protein ARP1, ARP1MGC20144, Brx1, Homeobox protein PITX2, IDG2, IGDS, IGDS2, IHG2, IRID2, Otlx2, paired-like homeodomain 2, Paired-like homeodomain transcription factor 2MGC111022, pituitary homeo box 2, pituitary homeobox 2, PTX2, RGS, RGSRIEG1Brx1, RIEG, RIEG bicoid-related homeobox transcription factor, rieg bicoid-related homeobox transcription factor 1, RIEG1, RP1, RS, solurshin
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.