product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Laminin alpha 4 Antibody
catalog :
AF7340
quantity :
100 ug (also 25 ug)
price :
469 USD
clonality :
polyclonal
host :
domestic sheep
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry
more info or order :
citations: 6
Reference
Saito Diaz K, Saini T, Patel A, James C, Thomas K, Knight T, et al. Laminin β4 is required for the development of human peripheral sensory neurons. bioRxiv. 2024;: pubmed publisher
Hsieh L, Hall B, Newcombe J, Mendum T, Santana Varela S, Umrania Y, et al. Mycolactone causes destructive Sec61-dependent loss of the endothelial glycocalyx and vessel basement membrane: a new indirect mechanism driving tissue necrosis in Mycobacterium ulcerans infection. bioRxiv. 2024;: pubmed publisher
Wang Y, Zheng S, Han J, Li N, Ji R, Li X, et al. LINC00629 protects osteosarcoma cell from ER stress-induced apoptosis and facilitates tumour progression by elevating KLF4 stability. J Exp Clin Cancer Res. 2022;41:354 pubmed publisher
Zheng B, Qu J, Ohuchida K, Feng H, Chong S, Yan Z, et al. LAMA4 upregulation is associated with high liver metastasis potential and poor survival outcome of Pancreatic Cancer. Theranostics. 2020;10:10274-10289 pubmed publisher
Béguin E, Janssen E, Hoogenboezem M, Meijer A, Hoogendijk A, van den Biggelaar M. Flow-induced Reorganization of Laminin-integrin Networks Within the Endothelial Basement Membrane Uncovered by Proteomics. Mol Cell Proteomics. 2020;19:1179-1192 pubmed publisher
Yan Y, Yu H, Sun L, Liu H, Wang C, Wei X, et al. Laminin α4 overexpression in the anterior lens capsule may contribute to the senescence of human lens epithelial cells in age-related cataract. Aging (Albany NY). 2019;11:2699-2723 pubmed publisher
product information
master code :
AF7340
SKU :
AF7340
product name :
Human Laminin alpha 4 Antibody
unit size :
100 ug (also 25 ug)
description :
The Human Laminin alpha 4 Antibody from R&D Systems is a sheep polyclonal antibody to Laminin alpha 4. This antibody reacts with human. The Human Laminin alpha 4 Antibody has been validated for the following applications: Western Blot,Immunocytochemistry,Migration Assay,Flow Cytometry,Neutralization,Immunohistochemistry,Simple Western.
target :
Laminin alpha 4
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Sheep
immunogen :
Chinese hamster ovary cell line CHO-derived recombinant human Laminin alpha 4, Gln826-Ala1816, predicted, Accession # EAW48267
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human
specificity :
Detects human Laminin alpha 4 in direct ELISAs and Western blots. In direct ELISAs, approximately 15% cross-reactivity with recombinant mouse Laminin alpha 4 is observed.
gene symbol :
LAMA4
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Detection of Human Laminin a4 antibody by Western Blot.
accessionNumbers :
EAW48267
applications :
Immunocytochemistry,Migration Assay,Flow Cytometry,Neutralization,Immunohistochemistry,Western Blot,Simple Western
USD :
469 USD
alt names :
DKFZp686D23145, LAMA3LAMA4*-1, LAMA4, laminin alpha 4 chain, laminin subunit alpha-4, laminin, alpha 4, Laminin-14 subunit alpha, Laminin-8 subunit alpha, Laminin-9 subunit alpha
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.