Mouse Spi-B Antibody | R&D Systems AF7204 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse Spi-B Antibody

catalog :

AF7204

quantity :

100 ug (also 25 ug)

price :

469 USD

clonality :

polyclonal

host :

domestic sheep

conjugate :

nonconjugated

reactivity :

mouse

application :

immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 8

Reference
Luna Velez M, Neikes H, Snabel R, Quint Y, Qian C, Martens A, et al. ONECUT2 regulates RANKL-dependent enterocyte and microfold cell differentiation in the small intestine; a multi-omics study. Nucleic Acids Res. 2023;51:1277-1296 pubmed publisher
Usami K, Niimi K, Matsuo A, Suyama Y, Sakai Y, Sato S, et al. The gut microbiota induces Peyer's-patch-dependent secretion of maternal IgA into milk. Cell Rep. 2021;36:109655 pubmed publisher
Kimura S, Nakamura Y, Kobayashi N, Shiroguchi K, Kawakami E, Mutoh M, et al. Osteoprotegerin-dependent M cell self-regulation balances gut infection and immunity. Nat Commun. 2020;11:234 pubmed publisher
Lai N, Musser M, Pinho Ribeiro F, Baral P, Jacobson A, Ma P, et al. Gut-Innervating Nociceptor Neurons Regulate Peyer's Patch Microfold Cells and SFB Levels to Mediate Salmonella Host Defense. Cell. 2020;180:33-49.e22 pubmed publisher
Sehgal A, Donaldson D, Pridans C, Sauter K, Hume D, Mabbott N. The role of CSF1R-dependent macrophages in control of the intestinal stem-cell niche. Nat Commun. 2018;9:1272 pubmed publisher
Kanaya T, Sakakibara S, Jinnohara T, Hachisuka M, Tachibana N, Hidano S, et al. Development of intestinal M cells and follicle-associated epithelium is regulated by TRAF6-mediated NF-κB signaling. J Exp Med. 2018;215:501-519 pubmed publisher
Donaldson D, Sehgal A, Rios D, Williams I, Mabbott N. Increased Abundance of M Cells in the Gut Epithelium Dramatically Enhances Oral Prion Disease Susceptibility. PLoS Pathog. 2016;12:e1006075 pubmed publisher
Sehgal A, Kobayashi A, Donaldson D, Mabbott N. c-Rel is dispensable for the differentiation and functional maturation of M cells in the follicle-associated epithelium. Immunobiology. 2017;222:316-326 pubmed publisher

product information

master code :

AF7204

SKU :

AF7204

product name :

Mouse Spi-B Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse Spi-B Antibody from R&D Systems is a sheep polyclonal antibody to Spi-B. This antibody reacts with mouse,transgenic mouse. The Mouse Spi-B Antibody has been validated for the following applications: Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,Intracellular Staining by Flow Cytometry,Immunocytochemistry,CyTOF-ready.

target :

Spi-B

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Sheep

immunogen :

E. coli -derived recombinant mouse Spi-B, Tyr18-Glu167 (Tyr110Phe), Accession # O35906

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Mouse,Transgenic Mouse

specificity :

Detects mouse Spi-B in direct ELISAs. In direct ELISAs, less than 2% cross-reactivity with recombinant human Spi-B is observed.

gene symbol :

SPIB

top caption :

Spi-B antibody in Mouse Splenocytes by Immunocytochemistry (ICC).

accessionNumbers :

O35906

applications :

Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,Intracellular Staining by Flow Cytometry,Immunocytochemistry,CyTOF-ready

USD :

469 USD

alt names :

SpiB, SPI-B, Spi-B transcription factor (Spi-1/PU.1 related), transcription factor Spi-B

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage