product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human ICAM-1/CD54 Antibody
catalog :
AF720
quantity :
100 ug (also 25 ug)
price :
499 USD
clonality :
polyclonal
host :
domestic sheep
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunocytochemistry, neutralization
more info or order :
citations: 5
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; fig 2b
Liu J, Shelkar G, Sarode L, Gawande D, Zhao F, Clausen R, et al. Facilitation of GluN2C-containing NMDA receptors in the external globus pallidus increases firing of fast spiking neurons and improves motor function in a hemiparkinsonian mouse model. Neurobiol Dis. 2021;150:105254 pubmed publisher
Himmels P, Nguyen T, Mitzner M, Arrazate A, Yeung S, Burton J, et al. T cell-dependent bispecific antibodies alter organ-specific endothelial cell-T cell interaction. EMBO Rep. 2023;24:e55532 pubmed publisher
Taftaf R, Liu X, Singh S, Jia Y, Dashzeveg N, Hoffmann A, et al. ICAM1 initiates CTC cluster formation and trans-endothelial migration in lung metastasis of breast cancer. Nat Commun. 2021;12:4867 pubmed publisher
Rivera Serrano E, Gonzalez Lopez O, Das A, Lemon S. Cellular entry and uncoating of naked and quasi-enveloped human hepatoviruses. elife. 2019;8: pubmed publisher
Genshaft A, Li S, Gallant C, Darmanis S, Prakadan S, Ziegler C, et al. Multiplexed, targeted profiling of single-cell proteomes and transcriptomes in a single reaction. Genome Biol. 2016;17:188 pubmed publisher
product information
brand :
R&D Systems
master code :
AF720
SKU :
AF720
product name :
Human ICAM-1/CD54 Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Human ICAM-1/CD54 Antibody from R&D Systems is a sheep polyclonal antibody to ICAM-1/CD54. This antibody reacts with human. The Human ICAM-1/CD54 Antibody has been validated for the following applications: Western Blot,Neutralization,Immunocytochemistry,Adhesion Blockade,Knockout Validated.
target :
ICAM-1/CD54
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 0.2 ug/mL, Adhesion Blockade, Immunocytochemistry 1-15 ug/mL, Knockout Validated 0.2 ug/mL
host :
Sheep
immunogen :
Chinese hamster ovary cell line CHO-derived recombinant human ICAM-1, Extracellular domain
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human
specificity :
Selected for its ability to block the adhesion of HSB-2 cells to immobilized recombinant human (rh) ICAM-1. In direct ELISAs, approximately 5% cross-reactivity with rhICAM-3 is observed and less than 2% cross-reactivity with rhICAM-2, rhICAM-4, rhICAM-5, recombinant rat ICAM-1, recombinant mouse ICAM-1, and rhVCAM-1 is observed.
gene symbol :
ICAM1
endotoxin note :
<0.20 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Detection of Human ICAM-1/CD54 antibody by Western Blot.
applications :
Adhesion Blockade,Knockout Validated,Western Blot,Neutralization,Immunocytochemistry
USD :
499 USD
alt names :
BB2, CD54, CD54 antigen, cell surface glycoprotein P3.58, human rhinovirus receptor, ICAM1, ICAM-1, intercellular adhesion molecule 1, intercellular adhesion molecule 1 (CD54), human rhinovirus receptor, Major group rhinovirus receptor, P3.58
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.