Human GFR alpha -1/GDNF R alpha -1 Antibody | R&D Systems AF714 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human GFR alpha -1/GDNF R alpha -1 Antibody

catalog :

AF714

quantity :

100 ug (also 25 ug)

price :

509 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse, dogs

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:2000; fig s1	Renko J, Mahato A, Visnapuu T, Valkonen K, Karelson M, Voutilainen M, et al. Neuroprotective Potential of a Small Molecule RET Agonist in Cultured Dopamine Neurons and Hemiparkinsonian Rats. J Parkinsons Dis. 2021;11:1023-1046 pubmed publisher
	Liu J, Prahl L, Huang A, Hughes A. Measurement of adhesion and traction of cells at high yield (MATCHY) reveals an energetic ratchet driving nephron condensation. bioRxiv. 2024;: pubmed publisher
	Rajachandran S, Zhang X, Cao Q, Caldeira Brant A, Zhang X, Song Y, et al. Dissecting the spermatogonial stem cell niche using spatial transcriptomics. Cell Rep. 2023;42:112737 pubmed publisher
	Choi Y, Jung J, Baek M, Khan S, Song P, Ryu S, et al. APE1 Promotes Pancreatic Cancer Proliferation through GFRα1/Src/ERK Axis-Cascade Signaling in Response to GDNF. Int J Mol Sci. 2020;21: pubmed publisher
	Ma W, Xu P, Liu Z, Zhou J, Gu L, Zhang J, et al. Impact of GFRA1 gene reactivation by DNA demethylation on prognosis of patients with metastatic colon cancer. World J Gastroenterol. 2020;26:184-198 pubmed publisher
	Tang R, Fan L. PLZFposc-KITpos-delineated A1-A4-differentiating spermatogonia by subset and stage detection upon Bouin fixation. Asian J Androl. 2019;21:309-318 pubmed publisher
	Bhakta S, Crocker L, Chen Y, Hazen M, Schutten M, Li D, et al. An Anti-GDNF Family Receptor Alpha 1 (GFRA1) Antibody-Drug Conjugate for the Treatment of Hormone Receptor-Positive Breast Cancer. Mol Cancer Ther. 2018;17:638-649 pubmed publisher

product information

master code :

AF714

SKU :

AF714

product name :

Human GFR alpha -1/GDNF R alpha -1 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human GFR alpha -1/GDNF R alpha -1 Antibody from R&D Systems is a goat polyclonal antibody to GFR alpha-1/GDNF R alpha-1. This antibody reacts with canine,guinea pig,human,mouse. The Human GFR alpha -1/GDNF R alpha -1 Antibody has been validated for the following applications: Western Blot,Immunocytochemistry,Immunohistochemistry,Flow Cytometry,Bioassay,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen.

target :

GFR alpha-1/GDNF R alpha-1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant human GFR alpha -1/GDNF R alpha -1, Met1-Lys429, Accession # NP_665736

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Canine,Guinea Pig,Human,Mouse

specificity :

Detects human GFR alpha -1/GDNF R alpha -1 in direct ELISAs and Western blots. In direct ELISAs, approximately 10% cross-reactivity with recombinant rat GFR alpha -1 is observed and less than 5% cross-reactivity with recombinant human (rh) GFR alpha -2, rhGFR alpha -3, and rhGFR alpha -4 is observed.

gene symbol :

GFRA1

top caption :

GFRa-1/GDNF Ra-1 antibody in Human Spinal Cord by Immunohistochemistry (IHC-P).

accessionNumbers :

NP_665736

applications :

Flow Cytometry,Western Blot,Bioassay,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry

USD :

509 USD

alt names :

DKFZp313E1012, DKFZp686J0156, GDNF family receptor alpha 1, GDNF family receptor alpha-1, GDNF R alpha-1, GDNF receptor alpha-1, GDNFRAGFR-ALPHA-1, GDNFR-alpha-1, GDNFRMGC23045, GFR alpha1, GFRa-1, GFRA1, GFR-alpha-1, Glial cell line-derived neurotrophic factor receptor alpha, GPI-linked anchor protein, PI-linked cell-surface accessory protein, RET ligand 1, RET1L, RETL1FLJ10561, TGF-beta related neurotrophic factor receptor 1, TGF-beta-related neurotrophic factor receptor 1, TRNR1FLJ31546

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage