product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human ARX Antibody
catalog :
AF7068
quantity :
100 ug (also 25 ug)
price :
519 USD
clonality :
polyclonal
host :
domestic sheep
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
R&D Systems product webpage
citations: 9
Reference
Zhang J, Jiang R, Hong X, Wu H, Han X, Wu W. Metastatic insulinoma: exploration from clinicopathological signatures and genetic characteristics. Front Oncol. 2023;13:1109330 pubmed publisher
Simon T, Riemer P, Jarosch A, Detjen K, Di Domenico A, Bormann F, et al. DNA methylation reveals distinct cells of origin for pancreatic neuroendocrine carcinomas and pancreatic neuroendocrine tumors. Genome Med. 2022;14:24 pubmed publisher
Dai X, Camunas Soler J, Briant L, Dos Santos T, Spigelman A, Walker E, et al. Heterogenous impairment of α cell function in type 2 diabetes is linked to cell maturation state. Cell Metab. 2022;34:256-268.e5 pubmed publisher
Haliyur R, Walker J, Sanyoura M, Reihsmann C, Shrestha S, Aramandla R, et al. Integrated Analysis of the Pancreas and Islets Reveals Unexpected Findings in Human Male With Type 1 Diabetes. J Endocr Soc. 2021;5:bvab162 pubmed publisher
Di Domenico A, Pipinikas C, Maire R, Br xe4 utigam K, Simillion C, Dettmer M, et al. Epigenetic landscape of pancreatic neuroendocrine tumours reveals distinct cells of origin and means of tumour progression. Commun Biol. 2020;3:740 pubmed publisher
Shi X, Lin W, Gao X, Xie W, Golden J, Tao T. Identification and validation of the phosphorylation sites on Aristaless-related homeobox protein. Biosci Rep. 2020;40: pubmed publisher
Moya N, Shahryari A, Burtscher I, Beckenbauer J, Bakhti M, Lickert H. Generation of a homozygous ARX nuclear CFP (ARXnCFP/nCFP) reporter human iPSC line (HMGUi001-A-4). Stem Cell Res. 2020;46:101874 pubmed publisher
Seiron P, Wiberg A, Kuric E, Krogvold L, Jahnsen F, Dahl Jørgensen K, et al. Characterisation of the endocrine pancreas in type 1 diabetes: islet size is maintained but islet number is markedly reduced. J Pathol Clin Res. 2019;5:248-255 pubmed publisher
Lam C, Chatterjee A, Shen E, Cox A, Kushner J. Low-Level Insulin Content Within Abundant Non-β Islet Endocrine Cells in Long-standing Type 1 Diabetes. Diabetes. 2019;68:598-608 pubmed publisher
product information
brand :
R&D Systems
catalog number base :
AF7068
SKU :
AF7068
product name :
Human ARX Antibody
units size :
100 ug (also 25 ug)
description :
The Human ARX Antibody from R&D Systems is a sheep polyclonal antibody to ARX. This antibody reacts with human,mouse,xenograft. The Human ARX Antibody has been validated for the following applications: Flow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry.
target :
ARX
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
all_available conjugate :
Unconjugated
host :
Sheep
immunogen :
E. coli -derived recombinant human ARX, Ser2-Ala100, Accession # Q96QS3
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse
specificity :
Detects human ARX in direct ELISAs and Western blots.
gene symbol :
ARX
top caption :
Detection of Human ARX antibody by Western Blot.
accessionNumbers :
Q96QS3
applications :
Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry
USD :
519 USD
alt names :
aristaless related homeobox, Aristaless-related homeobox, aristaless-related homeobox, X-linked, cancer/testis antigen 121, CT121, EIEE1, homeobox protein ARX, ISSX, ISSXmental retardation, X-linked 36, mental retardation, X-linked 29, mental retardation, X-linked 32, mental retardation, X-linked 33, mental retardation, X-linked 38, mental retardation, X-linked 43, mental retardation, X-linked 54, mental retardation, X-linked 76, mental retardation, X-linked 87, MRX29, MRX32, MRX33, MRX36, MRX38, MRX43, MRX54, MRX76, MRX87, MRXS1, PRTS
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.