product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse FoxC2 Antibody
catalog :
AF6989
quantity :
100 ug (also 25 ug)
price :
479 USD
clonality :
polyclonal
host :
domestic sheep
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 20
Reference
Yang S, Zeng Y, Jia X, Gu Y, Wood C, Yang R, et al. Activated dormant stem cells recover spermatogenesis in chemoradiotherapy-induced infertility. Cell Rep. 2024;43:114582 pubmed publisher
Chen D, Wiggins D, Sevick E, Davis M, King P. An EPHB4-RASA1 signaling complex inhibits shear stress-induced Ras-MAPK activation in lymphatic endothelial cells to promote the development of lymphatic vessel valves. bioRxiv. 2023;: pubmed publisher
Krup A, Winchester S, Ranade S, Agrawal A, Devine W, Sinha T, et al. A Mesp1-dependent developmental breakpoint in transcriptional and epigenomic specification of early cardiac precursors. Development. 2023;150: pubmed publisher
Wang S, Gong Y, Wang Z, Meng X, Luo Z, Papasian C, et al. Regulon active landscape reveals cell development and functional state changes of human primary osteoblasts in vivo. Hum Genomics. 2023;17:11 pubmed publisher
S xe1 ez M, Blassberg R, Camacho Aguilar E, Siggia E, Rand D, Briscoe J. Statistically derived geometrical landscapes capture principles of decision-making dynamics during cell fate transitions. Cell Syst. 2022;13:12-28.e3 pubmed publisher
Flora P, Li M, Galbo P, Astorkia M, Zheng D, Ezhkova E. Polycomb repressive complex 2 in adult hair follicle stem cells is dispensable for hair regeneration. PLoS Genet. 2021;17:e1009948 pubmed publisher
Czepielewski R, Erlich E, Onufer E, Young S, Saunders B, Han Y, et al. Ileitis-associated tertiary lymphoid organs arise at lymphatic valves and impede mesenteric lymph flow in response to tumor necrosis factor. Immunity. 2021;54:2795-2811.e9 pubmed publisher
Lindstr xf6 m N, Sealfon R, Chen X, Parvez R, Ransick A, De Sena Brandine G, et al. Spatial transcriptional mapping of the human nephrogenic program. Dev Cell. 2021;56:2381-2398.e6 pubmed publisher
Liu H, Zhang Z, Han Y, Fan A, Liu H, Zhang X, et al. The FENDRR/FOXC2 Axis Contributes to Multidrug Resistance in Gastric Cancer and Correlates With Poor Prognosis. Front Oncol. 2021;11:634579 pubmed publisher
Cha B, Ho Y, Geng X, Mahamud M, Chen L, Kim Y, et al. YAP and TAZ maintain PROX1 expression in the developing lymphatic and lymphovenous valves in response to VEGF-C signaling. Development. 2020;147: pubmed publisher
Frye M, Stritt S, Ortsäter H, Hernandez Vasquez M, Kaakinen M, Vicente A, et al. EphrinB2-EphB4 signalling provides Rho-mediated homeostatic control of lymphatic endothelial cell junction integrity. elife. 2020;9: pubmed publisher
Mikedis M, Fan Y, Nicholls P, Endo T, Jackson E, Cobb S, et al. DAZL mediates a broad translational program regulating expansion and differentiation of spermatogonial progenitors. elife. 2020;9: pubmed publisher
Norden P, Sabine A, Wang Y, Demir C, Liu T, Petrova T, et al. Shear stimulation of FOXC1 and FOXC2 differentially regulates cytoskeletal activity during lymphatic valve maturation. elife. 2020;9: pubmed publisher
Mahamud M, Geng X, Ho Y, Cha B, Kim Y, Ma J, et al. GATA2 controls lymphatic endothelial cell junctional integrity and lymphovenous valve morphogenesis through miR-126. Development. 2019;146: pubmed publisher
Qu X, Violette K, Sewell Loftin M, Soslow J, Saint Jean L, Hinton R, et al. Loss of flow responsive Tie1 results in Impaired
Aortic valve remodeling. Dev Biol. 2019;455:73-84 pubmed publisher
TRAN T, Lindström N, Ransick A, De Sena Brandine G, Guo Q, Kim A, et al. In Vivo Developmental Trajectories of Human Podocyte Inform In Vitro Differentiation of Pluripotent Stem Cell-Derived Podocytes. Dev Cell. 2019;50:102-116.e6 pubmed publisher
Nonomura K, Lukacs V, Sweet D, Goddard L, Kanie A, Whitwam T, et al. Mechanically activated ion channel PIEZO1 is required for lymphatic valve formation. Proc Natl Acad Sci U S A. 2018;115:12817-12822 pubmed publisher
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product information
master code :
AF6989
SKU :
AF6989
product name :
Mouse FoxC2 Antibody
unit size :
100 ug (also 25 ug)
description :
The Mouse FoxC2 Antibody from R&D Systems is a sheep polyclonal antibody to FoxC2. This antibody reacts with human,mouse,transgenic mouse,xenograft. The Mouse FoxC2 Antibody has been validated for the following applications: Flow Cytometry,Immunocytochemistry,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen.
target :
FoxC2
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Sheep
immunogen :
E. coli -derived recombinant mouse FoxC2, Ala412-Tyr494, Accession # Q61850
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Transgenic Mouse,Xenograft
specificity :
Detects mouse FoxC2 in direct ELISAs. In direct ELISAs, approximately 50% cross-reactivity with recombinant human (rh) FoxC2 is observed and less than 3% cross-reactivity with rhFoxF2 is observed.
gene symbol :
FOXC2
top caption :
FoxC2 antibody in Mouse Embryo by Immunohistochemistry (IHC-Fr).
accessionNumbers :
Q61850
applications :
Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen
USD :
479 USD
alt names :
Fkh14, FKHL14LD, forkhead box C2 (MFH-1, mesenchyme forkhead 1), forkhead, Drosophila, homolog-like 14, Forkhead-related protein FKHL14, LD, Mesenchyme fork head protein 1, mesenchyme forkhead 1, MFH1, MFH-1, MFH-1 protein, MFH1forkhead box protein C2, Transcription factor FKH-14
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.