product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse RANK/TNFRSF11A Antibody
catalog :
AF692
quantity :
100 ug (also 25 ug)
price :
479 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
R&D Systems product webpage
citations: 6
Reference
Northey J, Hayward M, Yui Y, Stashko C, Kai F, Mouw J, et al. Mechanosensitive hormone signaling promotes mammary progenitor expansion and breast cancer risk. Cell Stem Cell. 2024;31:106-126.e13 pubmed publisher
Yamamoto T, Abe M, Hongo H, Maruoka H, Yoshino H, Haraguchi Kitakamae M, et al. Differential osteoblastic activity in primary metaphyseal trabecular and secondary trabeculae of c-fos deficient mice. J Oral Biosci. 2023;65:265-272 pubmed publisher
Ju N, Hayashi H, Shimamura M, Yoshida S, Nakamaru R, Nakagami H, et al. Prevention of Acute Lung Injury by a Novel CD14-Inhibitory Receptor Activator of the NF-κB Ligand Peptide in Mice. Immunohorizons. 2021;5:438-447 pubmed publisher
Benítez S, Cordero A, Santamaria P, Redondo Pedraza J, Rocha A, Collado Solé A, et al. RANK links senescence to stemness in the mammary epithelia, delaying tumor onset but increasing tumor aggressiveness. Dev Cell. 2021;56:1727-1741.e7 pubmed publisher
Romeo S, Alawi K, Rodrigues J, Singh A, Kusumbe A, Ramasamy S. Endothelial proteolytic activity and interaction with non-resorbing osteoclasts mediate bone elongation. Nat Cell Biol. 2019;21:430-441 pubmed publisher
Jhun J, Lee S, Kim S, Ryu J, Kwon J, Na H, et al. RIPK1 inhibition attenuates experimental autoimmune arthritis via suppression of osteoclastogenesis. J Transl Med. 2019;17:84 pubmed publisher
product information
master code :
AF692
SKU :
AF692
product name :
Mouse RANK/TNFRSF11A Antibody
unit size :
100 ug (also 25 ug)
description :
The Mouse RANK/TNFRSF11A Antibody from R&D Systems is a goat polyclonal antibody to RANK/TNFRSF11A. This antibody reacts with human,mouse,transgenic mouse. The Mouse RANK/TNFRSF11A Antibody has been validated for the following applications: Immunohistochemistry,Agonist Activity,Flow Cytometry,Western Blot,Neutralization,Functional Assay,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen.
target :
RANK/TNFRSF11A
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse RANK/TNFRSF11A, Gln30-Pro213, Accession # O35305
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Transgenic Mouse
specificity :
Detects mouse RANK/TNFRSF11A in direct ELISAs and Western blots. In direct ELISAs, approximately 20% cross-reactivity with recombinant human RANK is observed.
gene symbol :
TNFRSF11A
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
RANK/TNFRSF11A antibody in Rat Embryo by Immunohistochemistry (IHC-Fr).
accessionNumbers :
O35305
applications :
Immunohistochemistry,Agonist Activity,Flow Cytometry,Western Blot,Neutralization,Functional Assay,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen
USD :
479 USD
alt names :
CD265, CD265 antigen, FEO, loss of heterozygosity, 18, chromosomal region 1, ODFR, ODFROSTS, OFE, OPTB7, Osteoclast differentiation factor receptor, PDB2, RANKLOH18CR1, Receptor activator of NF-KB, receptor activator of nuclear factor-kappa B, TNFRSF11A, TRANCE R, TRANCER, tumor necrosis factor receptor superfamily member 11A, tumor necrosis factor receptor superfamily, member 11a, activator of NFKB, tumor necrosis factor receptor superfamily, member 11a, NFKB activator
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.