product summary
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company name :
R&D Systems
product type :
antibody
product name :
Porcine IL-1▀/IL-1F2 Antibody
catalog :
AF681
quantity :
100 ug (also 25 ug)
price :
499 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
pigs
application :
western blot, immunocytochemistry, neutralization
more info or order :
citations: 4
Reference
Kiczak L, Pas x142 awska U, Go x17a dzik W, Adamik B, Zieli x144 ska M, Zieli x144 ski S, et al. Effect of low-dose hydrocortisone and inhaled nitric oxide on inflammatory mediators and local pulmonary metalloproteinases activity in LPS-induced sepsis in piglets. Sci Rep. 2023;13:11369 pubmed publisher
He S, Li L, Chen H, Hu X, Wang W, Zhang H, et al. PRRSV Infection Induces Gasdermin D-Driven Pyroptosis of Porcine Alveolar Macrophages through NLRP3 Inflammasome Activation. J Virol. 2022;96:e0212721 pubmed publisher
Zhu Z, Zhang X, Dong W, Wang X, He S, Zhang H, et al. TREM2 suppresses the proinflammatory response to facilitate PRRSV infection via PI3K/NF-κB signaling. PLoS Pathog. 2020;16:e1008543 pubmed publisher
Park H, Liu G, Thulasi Raman S, Landreth S, Liu Q, Zhou Y. NS1 Protein of 2009 Pandemic Influenza A Virus Inhibits Porcine NLRP3 Inflammasome-Mediated Interleukin-1 Beta Production by Suppressing ASC Ubiquitination. J Virol. 2018;92: pubmed publisher
product information
master code :
AF681
SKU :
AF681
product name :
Porcine IL-1▀/IL-1F2 Antibody
unit size :
100 ug (also 25 ug)
description :
The Porcine IL-1ß/IL-1F2 Antibody from R&D Systems is a goat polyclonal antibody to IL-1 beta/IL-1F2. This antibody reacts with porcine. The Porcine IL-1ß/IL-1F2 Antibody has been validated for the following applications: Co-Immunoprecipitation,Western Blot,Neutralization,Immunocytochemistry.
target :
IL-1 beta/IL-1F2
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
E. coli -derived recombinant porcine IL-1▀/IL-1F2, Ala115-Pro267, Accession # P26889
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Porcine
specificity :
Detects porcine IL-1▀/IL-1F2 in direct ELISAs and Western blots. In direct ELISAs, approximately 45%-75% cross-reactivity with recombinant human IL-1▀, recombinant mouse IL-1▀, recombinant rat IL-1▀, recombinant feline IL-1▀, recombinant canine IL-1▀, recombinant equine IL-1▀, recombinant guinea pig IL-1▀, recombinant rabbit IL-1▀, and recombinant rhesus monkey IL-1▀ is observed and less than 15% cross-reactivity with recombinant cotton rat IL-1▀ is observed.
gene symbol :
IL1B
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Cell Proliferation Induced by IL-1ss/IL-1F2 and Neutrali-zation by Porcine IL-1ss/IL-1F2 Antibody.
accessionNumbers :
P26889
applications :
Co-Immunoprecipitation,Western Blot,Neutralization,Immunocytochemistry
USD :
499 USD
alt names :
catabolin, IL-1, IL1 beta, IL-1 beta, IL-1b, IL1B, IL1-BETA, IL-1F2, IL1F2IL-1 beta, interleukin 1, beta, interleukin-1 beta, preinterleukin 1 beta, pro-interleukin-1-beta
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.