Human IGFBP-3 Antibody | R&D Systems AF675 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human IGFBP-3 Antibody

catalog :

AF675

quantity :

100 ug (also 25 ug)

price :

469 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 6

Reference
Chen Y, Tien S, Ko Y, Chang C, Hsu M, Chien H, et al. SEMA7A-mediated juxtacrine stimulation of IGFBP-3 upregulates IL-17RB at pancreatic cancer invasive front. Cancer Gene Ther. 2024;31:1840-1855 pubmed publisher
Zhao L, Wang Y, Mu P, Zhang X, Qi R, Zhang Y, et al. IGFBP3 induces PD-L1 expression to promote glioblastoma immune evasion. Cancer Cell Int. 2024;24:60 pubmed publisher
Furusaka Y, Inoue S, Mizoguchi I, Hasegawa H, Katahira Y, Watanabe A, et al. Potent antitumor effects of the conditioned medium of bone marrow-derived mesenchymal stem cells via IGFBP-4. Cancer Sci. 2023;114:2499-2514 pubmed publisher
Weigert A, Zheng X, Nenzel A, Turkowski K, G xfc nther S, Strack E, et al. Fibrocytes boost tumor-supportive phenotypic switches in the lung cancer niche via the endothelin system. Nat Commun. 2022;13:6078 pubmed publisher
Lloyd K, Parsons B, Burkitt M, Moore A, Papoutsopoulou S, Boyce M, et al. Netazepide Inhibits Expression of Pappalysin 2 in Type 1 Gastric Neuroendocrine Tumors. Cell Mol Gastroenterol Hepatol. 2020;10:113-132 pubmed publisher
Xiang Q, Liao Y, Chao H, Huang W, Liu J, Chen H, et al. ISL1 overexpression enhances the survival of transplanted human mesenchymal stem cells in a murine myocardial infarction model. Stem Cell Res Ther. 2018;9:51 pubmed publisher

product information

master code :

AF675

SKU :

AF675

product name :

Human IGFBP-3 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human IGFBP-3 Antibody from R&D Systems is a goat polyclonal antibody to IGFBP-3. This antibody reacts with human,mouse,primate - chlorocebus aethiops (african green monkey). The Human IGFBP-3 Antibody has been validated for the following applications: Neutralization,Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry.

target :

IGFBP-3

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant human IGFBP-3, Gly28-Lys291, Accession # CAA46087

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Primate - Chlorocebus aethiops (African Green Monkey)

specificity :

Detects human IGFBP-3 in direct ELISAs and Western blots. In direct ELISAs, approximately 10% cross reactivity with recombinant mouse IGFBP-3 is observed, and less than 1% cross-reactivity with recombinant human (rh) IGFBP-1, rhIGFBP-2, and rhIGFBP-4 is observed.

gene symbol :

IGFBP3

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

IGFBP-3 antibody in Human Colon by Immunohistochemistry (IHC-P).

accessionNumbers :

CAA46087

applications :

Neutralization,Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry

USD :

469 USD

alt names :

acid stable subunit of the 140 K IGF complex, binding protein 29, binding protein 53, growth hormone-dependent binding protein, IBP-3, IBP3BP-53, IGF-binding protein 3, IGFBP3, IGFBP-3, insulin-like growth factor binding protein 3, insulin-like growth factor-binding protein 3

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage