product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human IGFBP-2 Antibody
catalog :
AF674
quantity :
100 ug (also 25 ug)
price :
479 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human
application :
western blot, neutralization
more info or order :
R&D Systems product webpage
citations: 9
Reference
Conway J, Din xe7 D, Follain G, Paavolainen O, Kaivola J, Bostr xf6 m P, et al. IGFBP2 secretion by mammary adipocytes limits breast cancer invasion. Sci Adv. 2023;9:eadg1840 pubmed publisher
Alicea G, Portuallo M, Patel P, Fane M, Carey A, Speicher D, et al. Age-related increases in IGFBP2 increase melanoma cell invasion and lipid synthesis. bioRxiv. 2023;: pubmed publisher
Kunhiraman H, McSwain L, Shahab S, Gershon T, Macdonald T, Kenney A. IGFBP2 promotes proliferation and cell migration through STAT3 signaling in Sonic hedgehog medulloblastoma. Acta Neuropathol Commun. 2023;11:62 pubmed publisher
Zhang Y, Rabinovsky R, Wei Z, El Fatimy R, Deforzh E, Luan B, et al. Secreted PGK1 and IGFBP2 contribute to the bystander effect of miR-10b gene editing in glioma. Mol Ther Nucleic Acids. 2023;31:265-275 pubmed publisher
Weigert A, Zheng X, Nenzel A, Turkowski K, G xfc nther S, Strack E, et al. Fibrocytes boost tumor-supportive phenotypic switches in the lung cancer niche via the endothelin system. Nat Commun. 2022;13:6078 pubmed publisher
Shimizu M, Koma Y, Sakamoto H, Tsukamoto S, Kitamura Y, Urakami S, et al. Metallothionein 2A Expression in Cancer-Associated Fibroblasts and Cancer Cells Promotes Esophageal Squamous Cell Carcinoma Progression. Cancers (Basel). 2021;13: pubmed publisher
Tan X, Shi L, Banerjee P, Liu X, Guo H, Yu J, et al. A protumorigenic secretory pathway activated by p53 deficiency in lung adenocarcinoma. J Clin Invest. 2021;131: pubmed publisher
Mercurio L, Lulli D, Mascia F, Dellambra E, Scarponi C, Morelli M, et al. Intracellular Insulin-like growth factor binding protein 2 (IGFBP2) contributes to the senescence of keratinocytes in psoriasis by stabilizing cytoplasmic p21. Aging (Albany NY). 2020;12:6823-6851 pubmed publisher
Taechangam N, Iyer S, Walker N, Arzi B, Borjesson D. Mechanisms utilized by feline adipose-derived mesenchymal stem cells to inhibit T lymphocyte proliferation. Stem Cell Res Ther. 2019;10:188 pubmed publisher
product information
master code :
AF674
SKU :
AF674
product name :
Human IGFBP-2 Antibody
unit size :
100 ug (also 25 ug)
description :
The Human IGFBP-2 Antibody from R&D Systems is a goat polyclonal antibody to IGFBP-2. This antibody reacts with feline,human. The Human IGFBP-2 Antibody has been validated for the following applications: Neutralization,Western Blot,Simple Western.
target :
IGFBP-2
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant human IGFBP-2, Glu40-Gln328, Accession # CAA34373
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Feline,Human
specificity :
Detects human IGFBP-2 in direct ELISAs and Western blots.
gene symbol :
IGFBP2
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Detection of Human IGFBP-2 antibody by Western Blot.
accessionNumbers :
CAA34373
applications :
Western Blot,Neutralization,Simple Western
USD :
479 USD
alt names :
BP2, IBP2, IBP-2, IGF-binding protein 2, IGFBP2, IGFBP-2, IGF-BP53, insulin-like growth factor binding protein 2 (36kD), insulin-like growth factor binding protein 2, 36kDa, insulin-like growth factor-binding protein 2
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.