Human Phospho-PGC1 alpha (S571) Antibody | R&D Systems AF6650 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Phospho-PGC1 alpha (S571) Antibody

catalog :

AF6650

quantity :

100 ug (also 25 ug)

price :

399 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot

more info or order :

R&D Systems product webpage

citations: 13

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:1000; loading ...; fig s3e	Chen C, Hsu S, Chung T, Chu C, Wang H, Hsiao P, et al. Arginine is an epigenetic regulator targeting TEAD4 to modulate OXPHOS in prostate cancer cells. Nat Commun. 2021;12:2398 pubmed publisher
	Guo Z, Wang M, Ying X, Yuan J, Wang C, Zhang W, et al. Caloric restriction increases the resistance of aged heart to myocardial ischemia/reperfusion injury via modulating AMPK-SIRT1-PGC1a energy metabolism pathway. Sci Rep. 2023;13:2045 pubmed publisher
	Ogden S, Carys K, Ahmed I, Bruce J, Sharrocks A. Regulatory chromatin rewiring promotes metabolic switching during adaptation to oncogenic receptor tyrosine kinase inhibition. Oncogene. 2022;41:4808-4822 pubmed publisher
	Li X, Zhuge Z, Carvalho L, Braga V, Lucena R, Li S, et al. Inorganic nitrate and nitrite ameliorate kidney fibrosis by restoring lipid metabolism via dual regulation of AMP-activated protein kinase and the AKT-PGC1α pathway. Redox Biol. 2022;51:102266 pubmed publisher
	Miyagishima K, Sharma R, Nimmagadda M, Clore Gronenborn K, Qureshy Z, Ortolan D, et al. AMPK modulation ameliorates dominant disease phenotypes of CTRP5 variant in retinal degeneration. Commun Biol. 2021;4:1360 pubmed publisher
	van der Ende M, Plas R, van Dijk M, Dwarkasing J, van Gemerden F, Sarokhani A, et al. Effects of whole-body vibration training in a cachectic C26 mouse model. Sci Rep. 2021;11:21563 pubmed publisher
	Larson Casey J, Gu L, Davis D, Cai G, Ding Q, He C, et al. Post-translational regulation of PGC-1α modulates fibrotic repair. FASEB J. 2021;35:e21675 pubmed publisher
	Bucher M, Montaniel K, Myatt L, Weintraub S, Tavori H, Maloyan A. Dyslipidemia, insulin resistance, and impairment of placental metabolism in the offspring of obese mothers. J Dev Orig Health Dis. 2021;12:738-747 pubmed publisher
	Piers T, Cosker K, Mallach A, Johnson G, Guerreiro R, Hardy J, et al. A locked immunometabolic switch underlies TREM2 R47H loss of function in human iPSC-derived microglia. FASEB J. 2020;34:2436-2450 pubmed publisher
	Miao J, Liu J, Niu J, Zhang Y, Shen W, Luo C, et al. Wnt/β-catenin/RAS signaling mediates age-related renal fibrosis and is associated with mitochondrial dysfunction. Aging Cell. 2019;18:e13004 pubmed publisher
	Jeong H, Kang J, Jun H, Kim D, Park S, Sung M, et al. Chloroquine and amodiaquine enhance AMPK phosphorylation and improve mitochondrial fragmentation in diabetic tubulopathy. Sci Rep. 2018;8:8774 pubmed publisher
	Sajan M, Lee M, Foufelle F, Sajan J, Cleland C, Farese R. Coordinated regulation of hepatic FoxO1, PGC-1α and SREBP-1c facilitates insulin action and resistance. Cell Signal. 2018;43:62-70 pubmed publisher
	Bernard K, Logsdon N, Miguel V, Benavides G, Zhang J, Carter A, et al. NADPH Oxidase 4 (Nox4) Suppresses Mitochondrial Biogenesis and Bioenergetics in Lung Fibroblasts via a Nuclear Factor Erythroid-derived 2-like 2 (Nrf2)-dependent Pathway. J Biol Chem. 2017;292:3029-3038 pubmed publisher

product information

master code :

AF6650

SKU :

AF6650

product name :

Human Phospho-PGC1 alpha (S571) Antibody

unit size :

100 ug (also 25 ug)

description :

The Human Phospho-PGC1 alpha (S571) Antibody from R&D Systems is a rabbit polyclonal antibody to PGC1 alpha. This antibody reacts with human,mouse. The Human Phospho-PGC1 alpha (S571) Antibody has been validated for the following applications: Western Blot.

target :

PGC1 alpha

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

conjugate :

Unconjugated

host :

Rabbit

immunogen :

Phosphopeptide containing the human PGC1 alpha S571 site.

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse

specificity :

Detects human PGC1 alpha when phosphorylated at S571 in Western blots.

gene symbol :

PPARGC1A

top caption :

Detection of Human Phospho-PGC1a (S571) antibody by Western Blot.

applications :

Western Blot

USD :

399 USD

alt names :

LEM6, Ligand effect modulator 6, ligand effect modulator-6, L-PGC-1alpha, peroxisome proliferative activated receptor, gamma, coactivator 1, alpha, peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B4-3ext, peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B4-8a, peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B5-NT, peroxisome proliferator-activated receptor gamma coactivator 1-alpha, peroxisome proliferator-activated receptor gamma, coactivator 1 alpha, PGC1, PGC-1(alpha), PGC1A, PGC-1-alpha, PGC1APGC-1(alpha), PGC1peroxisome proliferative activated receptor, gamma, coactivator 1, PGC-1v, PPAR gamma coactivator variant form, PPAR gamma coactivator-1, PPARgamma coactivator 1alpha, PPAR-gamma coactivator 1-alpha, PPARGC1, PPARGC1A, PPARGC-1-alpha

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage