product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse OSMR▀ Antibody
catalog :
AF662
quantity :
100 ug (also 25 ug)
price :
469 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section, western blot knockout validation
more info or order :
citations: 7
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; 1:500; loading ...; fig s1a, s2b, s2e
Araujo A, Abaurrea A, Azcoaga P, L xf3 pez Velazco J, Manzano S, Rodriguez J, et al. Stromal oncostatin M cytokine promotes breast cancer progression by reprogramming the tumor microenvironment. J Clin Invest. 2022;132: pubmed publisher
  • western blot; mouse; 1:500; loading ...; fig 1d
Valussi M, Besser J, Wystub Lis K, Zukunft S, Richter M, Kubin T, et al. Repression of Osmr and Fgfr1 by miR-1/133a prevents cardiomyocyte dedifferentiation and cell cycle entry in the adult heart. Sci Adv. 2021;7:eabi6648 pubmed publisher
Bilgic S, Domaniku A, Toledo B, Agca S, Weber B, Arabaci D, et al. EDA2R-NIK signalling promotes muscle atrophy linked to cancer cachexia. Nature. 2023;617:827-834 pubmed publisher
Komori T, Morikawa Y. Essential roles of the cytokine oncostatin M in crosstalk between muscle fibers and immune cells in skeletal muscle after aerobic exercise. J Biol Chem. 2022;298:102686 pubmed publisher
L xf6 rchner H, Adrian Segarra J, Waechter C, Wagner R, G xf3 es M, Brachmann N, et al. Concomitant Activation of OSM and LIF Receptor by a Dual-Specific hlOSM Variant Confers Cardioprotection after Myocardial Infarction in Mice. Int J Mol Sci. 2021;23: pubmed publisher
Martínez Fábregas J, Prescott A, van Kasteren S, Pedrioli D, McLean I, Moles A, et al. Lysosomal protease deficiency or substrate overload induces an oxidative-stress mediated STAT3-dependent pathway of lysosomal homeostasis. Nat Commun. 2018;9:5343 pubmed publisher
Elks C, Zhao P, Grant R, Hang H, Bailey J, Burk D, et al. Loss of Oncostatin M Signaling in Adipocytes Induces Insulin Resistance and Adipose Tissue Inflammation in Vivo. J Biol Chem. 2016;291:17066-76 pubmed publisher
product information
master code :
AF662
SKU :
AF662
product name :
Mouse OSMR▀ Antibody
unit size :
100 ug (also 25 ug)
description :
The Mouse OSMRß Antibody from R&D Systems is a goat polyclonal antibody to OSMR beta. This antibody reacts with human,mouse,rat,transgenic mouse. The Mouse OSMRß Antibody has been validated for the following applications: Western Blot,ELISA Development,Flow Cytometry,Immunohistochemistry,Immunohistochemistry-Paraffin.
target :
OSMR beta
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse OSM R▀, Glu24-Leu738, Accession # O70458
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Rat,Transgenic Mouse
specificity :
Detects mouse OSM R▀ in direct ELISAs and Western blots.
gene symbol :
Osmr
accessionNumbers :
O70458
applications :
Western Blot,ELISA Development,Flow Cytometry,Immunohistochemistry,Immunohistochemistry-Paraffin
USD :
469 USD
alt names :
IL-31 receptor subunit beta, IL-31R subunit beta, IL-31RB, IL-31R-beta, Interleukin-31 receptor subunit beta, MGC150627, MGC75127, oncostatin M receptor, oncostatin-M specific receptor beta subunit, oncostatin-M-specific receptor subunit beta, OSM R beta, OSMR, OSMRB, OSMRBMGC150626, PLCA1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.