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company name :
R&D Systems
product type :
antibody
product name :
Mouse VCAM-1/CD106 Antibody
catalog :
AF643
quantity :
100 ug (also 25 ug)
price :
519 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
mouse
application :
western blot, immunohistochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 35
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; loading ...; fig 1e
  • western blot; mouse; loading ...; fig 1b
He Y, Li H, Yao J, Zhong H, Kuang Y, Li X, et al. HO‑1 knockdown upregulates the expression of VCAM‑1 to induce neutrophil recruitment during renal ischemia‑reperfusion injury. Int J Mol Med. 2021;48: pubmed publisher
  • immunohistochemistry; mouse; 1:100; fig 2g
Chelvanambi M, Fecek R, Taylor J, Storkus W. STING agonist-based treatment promotes vascular normalization and tertiary lymphoid structure formation in the therapeutic melanoma microenvironment. J Immunother Cancer. 2021;9: pubmed publisher
  • western blot; mouse; loading ...; fig 5a
Wang M, Murdoch C, Brewer A, Ivetic A, Evans P, Shah A, et al. Endothelial NADPH oxidase 4 protects against angiotensin II-induced cardiac fibrosis and inflammation. ESC Heart Fail. 2021;8:1427-1437 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 1h
Ruscetti M, Morris J, Mezzadra R, Russell J, Leibold J, Romesser P, et al. Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer. Cell. 2020;181:424-441.e21 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:20; loading ...; fig 3m
White E, Gyulay G, Lhotak S, Szewczyk M, Chong T, Fuller M, et al. Sialidase down-regulation reduces non-HDL cholesterol, inhibits leukocyte transmigration, and attenuates atherosclerosis in ApoE knockout mice. J Biol Chem. 2018;293:14689-14706 pubmed publisher
  • western blot; mouse; fig 3a
Choi H, Ettinger N, Rohrbough J, Dikalova A, Nguyen H, Lamb F. LRRC8A channels support TNF?-induced superoxide production by Nox1 which is required for receptor endocytosis. Free Radic Biol Med. 2016;101:413-423 pubmed publisher
Muto Y, Yoshimura Y, Wu H, Chang Panesso M, Ledru N, Woodward O, et al. Multi-omics profiling of mouse polycystic kidney disease progression at a single cell resolution. bioRxiv. 2024;: pubmed publisher
Manandhar S, Gaddam R, Chambers S, Bhatia M. Kupffer Cell Inactivation Alters Endothelial Cell Adhesion Molecules in Cecal Ligation and Puncture-Induced Sepsis. Biomolecules. 2024;14: pubmed publisher
Manandhar S, Chambers S, Miller A, Ishii I, Bhatia M. Pharmacological Inhibition and Genetic Deletion of Cystathionine Gamma-Lyase in Mice Protects against Organ Injury in Sepsis: A Key Role of Adhesion Molecules on Endothelial Cells. Int J Mol Sci. 2023;24: pubmed publisher
Yu L, Xu L, Chu H, Peng J, Sacharidou A, Hsieh H, et al. Macrophage-to-endothelial cell crosstalk by the cholesterol metabolite 27HC promotes atherosclerosis in male mice. Nat Commun. 2023;14:4101 pubmed publisher
Cerqueira A, Rodrigues L, Coavoy S xe1 nchez S, Teixeira S, Feitosa K, Taniguchi E, et al. Aedes aegypti salivary gland extract alleviates acute itching by blocking TRPA1 channels. Front Physiol. 2023;14:1055706 pubmed publisher
Zhang X, Li S, Malik I, Do M, Ji L, Chou C, et al. Reprogramming tumour-associated macrophages to outcompete cancer cells. Nature. 2023;619:616-623 pubmed publisher
Kim J, Yi M, Kim M, Choi J, Lee S, Yong T. Production of Dermatophagoides farinae Having Low Bacterial Content Using Ampicillin. J Immunol Res. 2023;2023:9024595 pubmed publisher
An H, Gwon M, Gu H, Bae S, Leem J, Lee J, et al. STAT3/NF‑κB decoy oligodeoxynucleotides inhibit atherosclerosis through regulation of the STAT/NF‑κB signaling pathway in a mouse model of atherosclerosis. Int J Mol Med. 2023;51: pubmed publisher
Uceda Castro R, Margarido A, Cornet L, Vegna S, Hahn K, Song J, et al. Re-purposing the pro-senescence properties of doxorubicin to introduce immunotherapy in breast cancer brain metastasis. Cell Rep Med. 2022;3:100821 pubmed publisher
Yu M, Hong K, Adili R, Mei L, Liu L, He H, et al. Development of activated endothelial targeted high-density lipoprotein nanoparticles. Front Pharmacol. 2022;13:902269 pubmed publisher
Coleman C, Stanley B, Lang C. Enrichment of Newly Synthesized Proteins following treatment of C2C12 Myotubes with Endotoxin and Interferon-γ. Inflammation. 2022;45:1313-1331 pubmed publisher
Koch P, Sandorski K, Heil J, Schmid C, K xfc rschner S, Hoffmann J, et al. Imbalanced Activation of Wnt-/β-Catenin-Signaling in Liver Endothelium Alters Normal Sinusoidal Differentiation. Front Physiol. 2021;12:722394 pubmed publisher
Sato K, Tobo A, Mogi C, Tobo M, Yamane N, Tosaka M, et al. The protective role of proton-sensing TDAG8 in the brain injury in a mouse ischemia reperfusion model. Sci Rep. 2020;10:17193 pubmed publisher
Jeong S, Cho M, Ko N, Kim S, Jung I, Min J, et al. Deficiency of peroxiredoxin 2 exacerbates angiotensin II-induced abdominal aortic aneurysm. Exp Mol Med. 2020;52:1587-1601 pubmed publisher
Colijn S, Muthukumar V, Xie J, Gao S, Griffin C. Cell-specific and athero-protective roles for RIPK3 in a murine model of atherosclerosis. Dis Model Mech. 2020;13: pubmed publisher
Choi H, Stark R, Raja B, Dikalova A, Lamb F. Apoptosis signal-regulating kinase 1 activation by Nox1-derived oxidants is required for TNFα receptor endocytosis. Am J Physiol Heart Circ Physiol. 2019;316:H1528-H1537 pubmed publisher
Liu X, Nemeth D, McKim D, Zhu L, DiSabato D, Berdysz O, et al. Cell-Type-Specific Interleukin 1 Receptor 1 Signaling in the Brain Regulates Distinct Neuroimmune Activities. Immunity. 2019;50:317-333.e6 pubmed publisher
Wohlrab P, Soto Gonzales L, Benesch T, Winter M, Lang I, Markstaller K, et al. Intermittent Hypoxia Activates Duration-Dependent Protective and Injurious Mechanisms in Mouse Lung Endothelial Cells. Front Physiol. 2018;9:1754 pubmed publisher
Moretti F, Klapproth S, Ruppert R, Margraf A, Weber J, Pick R, et al. Differential requirement of kindlin-3 for T cell progenitor homing to the non-vascularized and vascularized thymus. elife. 2018;7: pubmed publisher
Giles J, Greenhalgh A, Denes A, Nieswandt B, Coutts G, McColl B, et al. Neutrophil infiltration to the brain is platelet-dependent, and is reversed by blockade of platelet GPIbα. Immunology. 2018;154:322-328 pubmed publisher
Xu Y, Xu S, Liu P, Koroleva M, Zhang S, Si S, et al. Suberanilohydroxamic Acid as a Pharmacological Kruppel-Like Factor 2 Activator That Represses Vascular Inflammation and Atherosclerosis. J Am Heart Assoc. 2017;6: pubmed publisher
Li X, Kover K, Heruth D, Watkins D, Guo Y, Moore W, et al. Thioredoxin-interacting protein promotes high-glucose-induced macrovascular endothelial dysfunction. Biochem Biophys Res Commun. 2017;493:291-297 pubmed publisher
Akbar N, Digby J, Cahill T, Tavare A, Corbin A, Saluja S, et al. Endothelium-derived extracellular vesicles promote splenic monocyte mobilization in myocardial infarction. JCI Insight. 2017;2: pubmed publisher
Griger J, Schneider R, Lahmann I, Schöwel V, Keller C, Spuler S, et al. Loss of Ptpn11 (Shp2) drives satellite cells into quiescence. elife. 2017;6: pubmed publisher
Lin Y, Barske L, DeFalco T, Capel B. Numb regulates somatic cell lineage commitment during early gonadogenesis in mice. Development. 2017;144:1607-1618 pubmed publisher
Cui D, Li H, Lei L, Chen C, Yan F. Nonsurgical periodontal treatment reduced aortic inflammation in ApoE(-/-) mice with periodontitis. Springerplus. 2016;5:940 pubmed publisher
Liu T, Garofalo D, Feng C, Lai J, Katz H, Laidlaw T, et al. Platelet-driven leukotriene C4-mediated airway inflammation in mice is aspirin-sensitive and depends on T prostanoid receptors. J Immunol. 2015;194:5061-8 pubmed publisher
Nemeckova I, Serwadczak A, Oujo B, Ježková K, Rathouska J, Fikrová P, et al. High soluble endoglin levels do not induce endothelial dysfunction in mouse aorta. PLoS ONE. 2015;10:e0119665 pubmed publisher
Clement M, Guedj K, Andreata F, Morvan M, Bey L, Khallou Laschet J, et al. Control of the T follicular helper-germinal center B-cell axis by CD8⁺ regulatory T cells limits atherosclerosis and tertiary lymphoid organ development. Circulation. 2015;131:560-70 pubmed publisher
product information
master code :
AF643
SKU :
AF643
product name :
Mouse VCAM-1/CD106 Antibody
unit size :
100 ug (also 25 ug)
description :
The Mouse VCAM-1/CD106 Antibody from R&D Systems is a goat polyclonal antibody to VCAM-1/CD106. This antibody reacts with human,mouse,transgenic mouse. The Mouse VCAM-1/CD106 Antibody has been validated for the following applications: Immunohistochemistry,Western Blot,In vivo assay,Neutralization,Cell Selection,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Flow Cytometry,Simple Western,CyTOF-ready.
target :
VCAM-1/CD106
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse VCAM-1/CD106, Phe25-Glu698, Accession # P29533
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Mouse,Transgenic Mouse
specificity :
Detects mouse VCAM-1/CD106 in direct ELISAs and Western blots. In direct ELISA and Western blots, approximately 5% cross-reactivity with recombinant human VCAM-1 is observed.
gene symbol :
VCAM1
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Detection of Mouse VCAM-1/CD106 antibody by Western Blot.
accessionNumbers :
P29533
applications :
Immunohistochemistry,Western Blot,Neutralization,Cell Selection,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Flow Cytometry,Simple Western,CyTOF-ready
USD :
519 USD
alt names :
CD106, CD106 antigen, DKFZp779G2333, INCAM-100, L1CAM, MGC99561, vascular cell adhesion molecule 1, vascular cell adhesion protein 1, V-CAM 1, VCAM1, VCAM-1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.