product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse/Rat N-Cadherin Antibody
catalog :
AF6426
quantity :
100 ug (also 25 ug)
price :
539 USD
clonality :
polyclonal
host :
domestic sheep
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 16
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 6d
Fleming Martinez A, D xf6 ppler H, Bastea L, Edenfield B, Liou G, Storz P. Ym1+ macrophages orchestrate fibrosis, lesion growth, and progression during development of murine pancreatic cancer. iScience. 2022;25:104327 pubmed publisher
Despin Guitard E, Rosa V, Plunder S, Mathiah N, Van Schoor K, Nehme E, et al. Non-apical mitoses contribute to cell delamination during mouse gastrulation. Nat Commun. 2024;15:7364 pubmed publisher
Lass xe9 M, El Saghir J, Berthier C, Eddy S, Fischer M, Laufer S, et al. An integrated organoid omics map extends modeling potential of kidney disease. Nat Commun. 2023;14:4903 pubmed publisher
Rinschen M, Harder J, Carter Timofte M, Zanon Rodríguez L, Mirabelli C, Demir F, et al. VPS34-dependent control of apical membrane function of proximal tubule cells and nutrient recovery by the kidney. Sci Signal. 2022;15:eabo7940 pubmed publisher
Khadim R, Vadivelu R, Utami T, Torizal F, Nishikawa M, Sakai Y. Integrating Oxygen and 3D Cell Culture System: A Simple Tool to Elucidate the Cell Fate Decision of hiPSCs. Int J Mol Sci. 2022;23: pubmed publisher
Karnas K, Strączek T, Kapusta C, Lekka M, Dulinska Litewka J, Karewicz A. Specific Binding of Novel SPION-Based System Bearing Anti-N-Cadherin Antibodies to Prostate Tumor Cells. Int J Nanomedicine. 2021;16:6537-6552 pubmed publisher
Basak D, Jamal Z, Ghosh A, Mondal P, Dey Talukdar P, Ghosh S, et al. Reciprocal interplay between asporin and decorin: Implications in gastric cancer prognosis. PLoS ONE. 2021;16:e0255915 pubmed publisher
Scheidecker B, Shinohara M, Sugimoto M, Danoy M, Nishikawa M, Sakai Y. Induction of in vitro Metabolic Zonation in Primary Hepatocytes Requires Both Near-Physiological Oxygen Concentration and Flux. Front Bioeng Biotechnol. 2020;8:524 pubmed publisher
Velasco C, Llobet A. Synapse elimination activates a coordinated homeostatic presynaptic response in an autaptic circuit. Commun Biol. 2020;3:260 pubmed publisher
Wu J, Li Y, Chen A, Hong C, Zhang C, Wang H, et al. Inhibition of Sema4D/PlexinB1 signaling alleviates vascular dysfunction in diabetic retinopathy. EMBO Mol Med. 2020;12:e10154 pubmed publisher
Ikeda A, Shahid S, Blumberg B, Suzuki M, Bartlett J. ADAM10 is Expressed by Ameloblasts, Cleaves the RELT TNF Receptor Extracellular Domain and Facilitates Enamel Development. Sci Rep. 2019;9:14086 pubmed publisher
Ellis K, Driver E, Okano T, Lemons A, Kelley M. GSK3 regulates hair cell fate in the developing mammalian cochlea. Dev Biol. 2019;: pubmed publisher
Su Y, Bintz M, Yang Y, Robert L, Ng A, Liu V, et al. Phenotypic heterogeneity and evolution of melanoma cells associated with targeted therapy resistance. PLoS Comput Biol. 2019;15:e1007034 pubmed publisher
Harder J, Menon R, Otto E, Zhou J, Eddy S, Wys N, et al. Organoid single cell profiling identifies a transcriptional signature of glomerular disease. JCI Insight. 2019;4: pubmed publisher
Wan Y, Jin H, Zhu Y, Fang Z, Mao L, He Q, et al. MicroRNA-149-5p regulates blood-brain barrier permeability after transient middle cerebral artery occlusion in rats by targeting S1PR2 of pericytes. FASEB J. 2018;32:3133-3148 pubmed publisher
Cherubini E, Mariotta S, Scozzi D, Mancini R, Osman G, D Ascanio M, et al. BDNF/TrkB axis activation promotes epithelial-mesenchymal transition in idiopathic pulmonary fibrosis. J Transl Med. 2017;15:196 pubmed publisher
product information
brand :
R&D Systems
master code :
AF6426
SKU :
AF6426
product name :
Human/Mouse/Rat N-Cadherin Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Human/Mouse/Rat N-Cadherin Antibody from R&D Systems is a sheep polyclonal antibody to N-Cadherin. This antibody reacts with human,mouse,rat. The Human/Mouse/Rat N-Cadherin Antibody has been validated for the following applications: Immunohistochemistry,Flow Cytometry,Western Blot,Functional Assay,Immunohistochemistry-Paraffin,Immunocytochemistry,Immunocytochemistry/ Immunofluorescence,ELISA,CyTOF-ready.
target :
N-Cadherin
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 0.5 ug/mL, Flow Cytometry 0.25 ug/10^6 cells, ELISA, Immunohistochemistry 1-15 ug/mL, Immunocytochemistry 5-15 ug/mL, CyTOF-ready
host :
Sheep
immunogen :
Mouse myeloma cell line NS0-derived recombinant human N-Cadherin, Asp160-Ala724, Accession # P19022
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Rat
specificity :
Detects human, mouse, and rat N-Cadherin in Western blots. In direct ELISA, less than 10% cross-reactivity with recombinant human (rh) E-Cadherin, and rhR-Cadherin is observed.
gene symbol :
CDH2
top caption :
Detection of Human, Mouse, and Rat N-Cadherin antibody by Western Blot.
accessionNumbers :
P19022
applications :
ELISA,CyTOF-ready,Flow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry,Functional Assay,Immunocytochemistry/ Immunofluorescence
USD :
539 USD
alt names :
ACOGS, ARVD14, cadherin 2, type 1, N-cadherin (neuronal), cadherin-2, calcium-dependent adhesion protein, neuronal, CD325, CD325 antigen, CDH2, CDHN, CDw325, NCAD, N-cadherin, NCadherin, N-cadherin 1, Neural cadherin, neural-cadherin
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.