product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse EphA4 Antibody
catalog :
AF641
quantity :
100 ug (also 25 ug)
price :
499 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - frozen section
more info or order :
citations: 8
Reference
Altounian M, Bellon A, Mann F. Neuronal miR-17-5p contributes to interhemispheric cortical connectivity defects induced by prenatal alcohol exposure. Cell Rep. 2023;42:113020 pubmed publisher
Lewis A, Kuwahara A, Franzosi J, Bush J. Tracheal separation is driven by NKX2-1-mediated repression of Efnb2 and regulation of endodermal cell sorting. Cell Rep. 2022;38:110510 pubmed publisher
Tran Anh K, Zhang J, Nguyen Minh V, Fujita H, Hirata T, Sugihara I. Common Origin of the Cerebellar Dual Somatotopic Areas Revealed by Tracking Embryonic Purkinje Cell Clusters with Birthdate Tagging. Eneuro. 2020;7: pubmed publisher
Hoek J, Hepkema W, Halffman W. The effect of journal guidelines on the reporting of antibody validation. Peerj. 2020;8:e9300 pubmed publisher
García Diaz B, Bachelin C, Coulpier F, Gerschenfeld G, Deboux C, Zujovic V, et al. Blood vessels guide Schwann cell migration in the adult demyelinated CNS through Eph/ephrin signaling. Acta Neuropathol. 2019;: pubmed publisher
Zhang Z, Tremblay J, Raelson J, Sofer T, Du L, Fang Q, et al. EPHA4 regulates vascular smooth muscle cell contractility and is a sex-specific hypertension risk gene in individuals with type 2 diabetes. J Hypertens. 2019;37:775-789 pubmed publisher
Collinson J, Lindström N, Neves C, Wallace K, Meharg C, Charles R, et al. The developmental and genetic basis of 'clubfoot' in the peroneal muscular atrophy mutant mouse. Development. 2018;145: pubmed publisher
Todd K, Baker K, Eastman M, Kolling F, Trausch A, Nelson C, et al. EphA4 Regulates Neuroblast and Astrocyte Organization in a Neurogenic Niche. J Neurosci. 2017;37:3331-3341 pubmed publisher
product information
master code :
AF641
SKU :
AF641
product name :
Mouse EphA4 Antibody
unit size :
100 ug (also 25 ug)
description :
The Mouse EphA4 Antibody from R&D Systems is a goat polyclonal antibody to EphA4. This antibody reacts with mouse,rat. The Mouse EphA4 Antibody has been validated for the following applications: Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Frozen,Immunofluorescence.
target :
EphA4
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse EphA4, Val20-Thr547, Accession # Q03137
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Mouse,Rat
specificity :
Detects mouse EphA4 in direct ELISAs and Western blots. In direct ELISAs, approximately 50% cross-reactivity with recombinant human EphA4 is observed, and less than 5% cross-reactivity with recombinant mouse (rm) EphA3, rmEphA6, rmEphA7, and rmEphA8 is observed.
gene symbol :
EPHA4
top caption :
EphA4 antibody in Embryonic Rat Rib Cartilage Primordium by Immunohistochemistry (IHC-Fr).
accessionNumbers :
Q03137
applications :
Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Frozen,Immunofluorescence
USD :
499 USD
alt names :
Cek8, EC 2.7.10, EC 2.7.10.1, EK8, EPH receptor A4, EphA4, EPH-like kinase 8, ephrin type-A receptor 4, HEK8, receptor protein-tyrosine kinase HEK8, SEK, Sek1, Tyro1, TYRO1 protein tyrosine kinase, Tyrosine-protein kinase receptor SEK, Tyrosine-protein kinase TYRO1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.