Human Activin RIA/ALK-2 Antibody | R&D Systems AF637 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Activin RIA/ALK-2 Antibody

catalog :

AF637

quantity :

100 ug (also 25 ug)

price :

489 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, rat

application :

western blot, immunohistochemistry, flow cytometry

more info or order :

R&D Systems product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; rat; 1:100; loading ...; fig 4a	Lin W, Zhang W, Lyu N, Cao H, Xu W, Zhang Y. Growth Differentiation Factor-15 Produces Analgesia by Inhibiting Tetrodotoxin-Resistant Nav1.8 Sodium Channel Activity in Rat Primary Sensory Neurons. Neurosci Bull. 2021;37:1289-1302 pubmed publisher
	Lees Shepard J, Stoessel S, Chandler J, Bouchard K, Bento P, Apuzzo L, et al. An anti-ACVR1 antibody exacerbates heterotopic ossification by fibro-adipogenic progenitors in fibrodysplasia ossificans progressiva mice. J Clin Invest. 2022;132: pubmed publisher
	Dhakal P, Tsunoda N, Nambo Y, Taniyama H, Nagaoka K, Watanabe G, et al. Circulating activin A during equine gestation and immunolocalization of its receptors system in utero-placental tissues and fetal gonads. J Equine Sci. 2021;32:39-48 pubmed publisher
	Chauvin M, Garambois V, Choblet S, Colombo P, Chentouf M, Gros L, et al. Anti-Müllerian hormone concentration regulates activin receptor-like kinase-2/3 expression levels with opposing effects on ovarian cancer cell survival. Int J Oncol. 2021;59: pubmed publisher
	Toofan P, Busch C, Morrison H, O Brien S, Jørgensen H, Copland M, et al. Chronic myeloid leukaemia cells require the bone morphogenic protein pathway for cell cycle progression and self-renewal. Cell Death Dis. 2018;9:927 pubmed publisher
	Tengroth L, Arebro J, Larsson O, Bachert C, Georén S, Cardell L. Activation of Activin receptor-like kinases curbs mucosal inflammation and proliferation in chronic rhinosinusitis with nasal polyps. Sci Rep. 2018;8:1561 pubmed publisher

product information

master code :

AF637

SKU :

AF637

product name :

Human Activin RIA/ALK-2 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human Activin RIA/ALK-2 Antibody from R&D Systems is a goat polyclonal antibody to Activin RIA/ALK-2/Activin Receptor Type 1. This antibody reacts with human. The Human Activin RIA/ALK-2 Antibody has been validated for the following applications: Flow Cytometry,Western Blot,Immunohistochemistry,CyTOF-ready.

target :

Activin RIA/ALK-2

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Activin RIA/ALK-2, Asp23-Glu123, Accession # Q04771

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human

specificity :

Detects human Activin RIA/ALK-2 in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant human (rh) Activin RIB, rhActivin RIIA, and rhActivin RIIB is observed.

gene symbol :

ACVR1

top caption :

Detection of Activin RIA/ALK-2 antibody in PC-3 Human Cell Line antibody by Flow Cytometry.

accessionNumbers :

Q04771

applications :

Flow Cytometry,Western Blot,Immunohistochemistry,CyTOF-ready

USD :

489 USD

alt names :

activin A receptor, type I, ActivinRIA, ACTRI, ACVR1, ACVR1A, ACVRLK2, ALK2, ALK-2, FOP, SKR1, TSRI

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage