Human TRAILR4/TNFRSF10D Antibody | R&D Systems AF633 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human TRAILR4/TNFRSF10D Antibody

catalog :

AF633

quantity :

100 ug (also 25 ug)

price :

469 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 3

Reference
Kopczynski M, Statkiewicz M, Cybulska M, Kuklinska U, Unrug Bielawska K, Sandowska Markiewicz Z, et al. Cytotoxic Efficacy and Resistance Mechanism of a TRAIL and VEGFA-Peptide Fusion Protein in Colorectal Cancer Models. Int J Mol Sci. 2021;22: pubmed publisher
Аrtykov А, Belov D, Shipunova V, Trushina D, Deyev S, Dolgikh D, et al. Chemotherapeutic Agents Sensitize Resistant Cancer Cells to the DR5-Specific Variant DR5-B more Efficiently than to TRAIL by Modulating the Surface Expression of Death and Decoy Receptors. Cancers (Basel). 2020;12: pubmed publisher
Shlyakhtina Y, Pavet V, Gronemeyer H. Dual role of DR5 in death and survival signaling leads to TRAIL resistance in cancer cells. Cell Death Dis. 2017;8:e3025 pubmed publisher

product information

master code :

AF633

SKU :

AF633

product name :

Human TRAILR4/TNFRSF10D Antibody

unit size :

100 ug (also 25 ug)

description :

The Human TRAILR4/TNFRSF10D Antibody from R&D Systems is a goat polyclonal antibody to TRAILR4/TNFRSF10D/DcR2. This antibody reacts with human. The Human TRAILR4/TNFRSF10D Antibody has been validated for the following applications: Flow Cytometry,Immunoprecipitation,Western Blot,Neutralization,Cell Culture,Immunohistochemistry-Paraffin,Immunocytochemistry,ELISA,Immunohistochemistry,CyTOF-ready.

target :

TRAILR4/TNFRSF10D

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant human TRAIL R4/TNFRSF10D, Ala56-His211, Accession # Q9UBN6

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human

specificity :

Detects human TRAIL R4/TNFRSF10D in direct ELISAs and Western blots. In Western blots, less than 5% cross-reactivity with recombinant human (rh) TRAIL R1, rhTRAIL R2, and rhTRAIL R3 is observed.

gene symbol :

TNFRSF10D

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

accessionNumbers :

Q9UBN6

applications :

Flow Cytometry,Immunoprecipitation,Western Blot,Neutralization,Cell Culture,Immunohistochemistry-Paraffin,Immunocytochemistry,ELISA,Immunohistochemistry,CyTOF-ready

USD :

469 USD

alt names :

CD264, CD264 antigen, DcR2, DCR2decoy with truncated death domain, Decoy receptor 2, TNF receptor-related receptor for TRAIL, TNF-related apoptosis-inducing ligand receptor 4, TNFRSF10D, TRAIL R4, TRAIL-R4, TRAILR4TRAIL receptor 4, TRUNDDTRAIL receptor with a truncated death domain, tumor necrosis factor receptor superfamily member 10D, tumor necrosis factor receptor superfamily, member 10d, decoy with truncateddeath domain

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage