product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human TRAIL R3/TNFRSF10C Antibody
catalog :
AF630
quantity :
100 ug (also 25 ug)
price :
469 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 3
Reference
Höfle J, Trenkner T, Kleist N, Schwane V, Vollmers S, Barcelona B, et al. Engagement of TRAIL triggers degranulation and IFNγ production in human natural killer cells. EMBO Rep. 2022;:e54133 pubmed publisher
Kopczynski M, Statkiewicz M, Cybulska M, Kuklinska U, Unrug Bielawska K, Sandowska Markiewicz Z, et al. Cytotoxic Efficacy and Resistance Mechanism of a TRAIL and VEGFA-Peptide Fusion Protein in Colorectal Cancer Models. Int J Mol Sci. 2021;22: pubmed publisher
Аrtykov А, Belov D, Shipunova V, Trushina D, Deyev S, Dolgikh D, et al. Chemotherapeutic Agents Sensitize Resistant Cancer Cells to the DR5-Specific Variant DR5-B more Efficiently than to TRAIL by Modulating the Surface Expression of Death and Decoy Receptors. Cancers (Basel). 2020;12: pubmed publisher
product information
master code :
AF630
SKU :
AF630
product name :
Human TRAIL R3/TNFRSF10C Antibody
unit size :
100 ug (also 25 ug)
description :
The Human TRAIL R3/TNFRSF10C Antibody from R&D Systems is a goat polyclonal antibody to TRAILR3/TNFRSF10C. This antibody reacts with human. The Human TRAIL R3/TNFRSF10C Antibody has been validated for the following applications: Flow Cytometry,Western Blot,Neutralization,Cell Culture,Immunohistochemistry-Paraffin,Immunocytochemistry,Immunohistochemistry.
target :
TRAIL R3/TNFRSF10C
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant human TRAIL R3/TNFRSF10C, Ala26-Ala221, Accession # O14798
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human
specificity :
Detects human TRAIL R3/TNFRSF10C in direct ELISAs and Western blots. In direct ELISAs, less than 5% cross-reactivity with recombinant human (rh) TRAIL R1, and rhTRAIL R2 is observed.
gene symbol :
TNFRSF10C
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Detection of Human TRAIL R3/TNFRSF10C antibody by Western Blot.
accessionNumbers :
O14798
applications :
Flow Cytometry,Western Blot,Neutralization,Cell Culture,Immunohistochemistry-Paraffin,Immunocytochemistry,Immunohistochemistry
USD :
469 USD
alt names :
Antagonist decoy receptor for TRAIL/Apo-2L, CD263, CD263 antigen, cytotoxic TRAIL receptor-3, DcR1, DCR1MGC149502, Decoy receptor 1, Decoy TRAIL receptor without death domain, LITMGC149501, Lymphocyte inhibitor of TRAIL, TNFRSF10C, TRAIL receptor 3, TRAIL receptor without an intracellular domain, TRAILR3, TRAIL-R3, TRAILR3TNF-related apoptosis-inducing ligand receptor 3, TRIDDCR1-TNFR, tumor necrosis factor receptor superfamily member 10C, tumor necrosis factor receptor superfamily, member 10c, decoy without anintracellular domain
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.