product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human ONECUT2/OC-2 Antibody
catalog :
AF6294
quantity :
100 ug (also 25 ug)
price :
479 USD
clonality :
polyclonal
host :
domestic sheep
conjugate :
nonconjugated
reactivity :
human, mouse
application :
immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
R&D Systems product webpage
citations: 12
Reference
Mehta K, Daghsni M, Raeisossadati R, Xu Z, Davis E, Naidich A, et al. A cis-regulatory module underlies retinal ganglion cell genesis and axonogenesis. Cell Rep. 2024;43:114291 pubmed publisher
Zhang J, Roberts J, Chang F, Schwakopf J, Vetter M. Jarid2 promotes temporal progression of retinal progenitors via repression of Foxp1. Cell Rep. 2023;42:112237 pubmed publisher
Romanov R, Tretiakov E, Kastriti M, Zupancic M, Häring M, Korchynska S, et al. Molecular design of hypothalamus development. Nature. 2020;582:246-252 pubmed publisher
Lu Y, Shiau F, Yi W, Lu S, Wu Q, Pearson J, et al. Single-Cell Analysis of Human Retina Identifies Evolutionarily Conserved and Species-Specific Mechanisms Controlling Development. Dev Cell. 2020;53:473-491.e9 pubmed publisher
Sridhar A, Hoshino A, Finkbeiner C, Chitsazan A, Dai L, Haugan A, et al. Single-Cell Transcriptomic Comparison of Human Fetal Retina, hPSC-Derived Retinal Organoids, and Long-Term Retinal Cultures. Cell Rep. 2020;30:1644-1659.e4 pubmed publisher
Toch M, Harris A, Schakman O, Kondratskaya E, Boulland J, Dauguet N, et al. Onecut-dependent Nkx6.2 transcription factor expression is required for proper formation and activity of spinal locomotor circuits. Sci Rep. 2020;10:996 pubmed publisher
Wei R, Ren X, Kong H, Lv Z, Chen Y, Tang Y, et al. Rb1/Rbl1/Vhl loss induces mouse subretinal angiomatous proliferation and hemangioblastoma. JCI Insight. 2019;4: pubmed publisher
Janeckova L, Kostovcikova K, Svec J, Stastna M, Strnad H, Kolar M, et al. Unique Gene Expression Signatures in the Intestinal Mucosa and Organoids Derived from Germ-Free and Monoassociated Mice. Int J Mol Sci. 2019;20: pubmed publisher
Zhou Y, Wei R, Zhang L, Chen Y, Lu S, Liang C, et al. Rb is required for retinal angiogenesis and lamination. Cell Death Dis. 2018;9:370 pubmed publisher
Sweeney L, Bikoff J, Gabitto M, Brenner Morton S, Baek M, Yang J, et al. Origin and Segmental Diversity of Spinal Inhibitory Interneurons. Neuron. 2018;97:341-355.e3 pubmed publisher
Kabayiza K, Masgutova G, Harris A, Rucchin V, Jacob B, Clotman F. The Onecut Transcription Factors Regulate Differentiation and Distribution of Dorsal Interneurons during Spinal Cord Development. Front Mol Neurosci. 2017;10:157 pubmed publisher
Velasco S, Ibrahim M, Kakumanu A, Garipler G, Aydin B, Al Sayegh M, et al. A Multi-step Transcriptional and Chromatin State Cascade Underlies Motor Neuron Programming from Embryonic Stem Cells. Cell Stem Cell. 2017;20:205-217.e8 pubmed publisher
product information
brand :
R&D Systems
master code :
AF6294
SKU :
AF6294
product name :
Human ONECUT2/OC-2 Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Human ONECUT2/OC-2 Antibody from R&D Systems is a sheep polyclonal antibody to ONECUT2/OC-2. This antibody reacts with human,mouse,transgenic mouse. The Human ONECUT2/OC-2 Antibody has been validated for the following applications: Immunohistochemistry,Flow Cytometry,Immunoprecipitation,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry.
target :
ONECUT2/OC-2
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Immunocytochemistry 5-15 ug/mL
host :
Sheep
immunogen :
E. coli -derived recombinant human ONECUT2/OC-2, Gln185-Thr326, Accession # O95948
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Transgenic Mouse
specificity :
Detects human ONECUT2/OC-2 in direct ELISAs.
gene symbol :
ONECUT2
top caption :
ONECUT2/OC-2 antibody in HepG2 Human Cell Line by Immunocytochemistry (ICC).
accessionNumbers :
O95948
applications :
Flow Cytometry,Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry
USD :
479 USD
alt names :
one cut domain family member 2, HNF-6B, OC2, OC-2, one cut homeobox 2
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.