product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Pro Collagen I alpha 1 Antibody
catalog :
AF6220
quantity :
100 ug (also 25 ug)
price :
499 USD
clonality :
polyclonal
host :
domestic sheep
conjugate :
nonconjugated
reactivity :
human, mouse, rhesus macaque
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
more info or order :
R&D Systems product webpage
citations: 20
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; human; 1:75; loading ...
Tian C, Huang Y, Clauser K, Rickelt S, Lau A, Carr S, et al. Suppression of pancreatic ductal adenocarcinoma growth and metastasis by fibrillar collagens produced selectively by tumor cells. Nat Commun. 2021;12:2328 pubmed publisher
Faust H, Cheng T, Korsunsky I, Watts G, Gal Oz S, Trim W, et al. Adipocyte associated glucocorticoid signaling regulates normal fibroblast function which is lost in inflammatory arthritis. Nat Commun. 2024;15:9859 pubmed publisher
Jocher J, Edenhofer F, M xfc ller S, Janssen P, Briem E, Geuder J, et al. Generation and characterization of two Vervet monkey induced pluripotent stem cell lines derived from fibroblasts. Stem Cell Res. 2024;75:103315 pubmed publisher
Jocher J, Edenhofer F, M xfc ller S, Janssen P, Briem E, Geuder J, et al. Generation and characterization of two fibroblast-derived Baboon induced pluripotent stem cell lines. Stem Cell Res. 2024;75:103316 pubmed publisher
Park S, Park C, Eom J, Jo M, Hur H, Choi S, et al. Preclinical and dose-ranging assessment of hESC-derived dopaminergic progenitors for a clinical trial on Parkinson's disease. Cell Stem Cell. 2024;31:25-38.e8 pubmed publisher
Maimaitili M, Chen M, Febbraro F, Ucuncu E, Kelly R, Niclis J, et al. Enhanced production of mesencephalic dopaminergic neurons from lineage-restricted human undifferentiated stem cells. Nat Commun. 2023;14:7871 pubmed publisher
Faust H, Cheng T, Korsunsky I, Watts G, Gal Oz S, Trim W, et al. Adipocytes regulate fibroblast function, and their loss contributes to fibroblast dysfunction in inflammatory diseases. bioRxiv. 2023;: pubmed publisher
R xe1 jov xe1 J, Davidsson M, Avallone M, Hartnor M, Aldrin Kirk P, Cardoso T, et al. Deconvolution of spatial sequencing provides accurate characterization of hESC-derived DA transplants in vivo. Mol Ther Methods Clin Dev. 2023;29:381-394 pubmed publisher
Ryoo H, Underhill G. Combinatorial Microgels for 3D ECM Screening and Heterogeneous Microenvironmental Culture of Primary Human Hepatic Stellate Cells. bioRxiv. 2023;: pubmed publisher
You Z, Wang L, He H, Wu Z, Zhang X, Xue S, et al. Mapping of clonal lineages across developmental stages in human neural differentiation. Cell Stem Cell. 2023;30:473-487.e9 pubmed publisher
Beznoussenko G, Kweon H, Sesorova I, Mironov A. Comparison of the Cisterna Maturation-Progression Model with the Kiss-and-Run Model of Intra-Golgi Transport: Role of Cisternal Pores and Cargo Domains. Int J Mol Sci. 2022;23: pubmed publisher
Foster J, Parikh R, Wang J, Bower K, Matthaei M, Chakravarti S, et al. Transcriptomic and Immunohistochemical Analysis of Progressive Keratoconus Reveal Altered WNT10A in Epithelium and Bowman's Layer. Invest Ophthalmol Vis Sci. 2021;62:16 pubmed publisher
Rao V, Stubbs E. TGF-β2 Promotes Oxidative Stress in Human Trabecular Meshwork Cells by Selectively Enhancing NADPH Oxidase 4 Expression. Invest Ophthalmol Vis Sci. 2021;62:4 pubmed publisher
Hu L, Liu J, Xue H, Panayi A, Xie X, Lin Z, et al. miRNA-92a-3p regulates osteoblast differentiation in patients with concomitant limb fractures and TBI via IBSP/PI3K-AKT inhibition. Mol Ther Nucleic Acids. 2021;23:1345-1359 pubmed publisher
Tao Y, Vermilyea S, Zammit M, Lu J, Olsen M, Metzger J, et al. Autologous transplant therapy alleviates motor and depressive behaviors in parkinsonian monkeys. Nat Med. 2021;27:632-639 pubmed publisher
Piao J, Zabierowski S, Dubose B, Hill E, Navare M, Claros N, et al. Preclinical Efficacy and Safety of a Human Embryonic Stem Cell-Derived Midbrain Dopamine Progenitor Product, MSK-DA01. Cell Stem Cell. 2021;28:217-229.e7 pubmed publisher
Wang Z, Cheng Z, Abrams S, Lin Z, Yates E, Yu Q, et al. Extracellular histones stimulate collagen expression in vitro and promote liver fibrogenesis in a mouse model via the TLR4-MyD88 signaling pathway. World J Gastroenterol. 2020;26:7513-7527 pubmed publisher
Cheng N, Tu Y, Lee N, Young T. Influence of Human Platelet Lysate on Extracellular Matrix Deposition and Cellular Characteristics in Adipose-Derived Stem Cell Sheets. Front Cell Dev Biol. 2020;8:558354 pubmed publisher
Othman R, Berbari S, Vaucher E, Couture R. Differential Expression of Kinin Receptors in Human Wet and Dry Age-Related Macular Degeneration Retinae. Pharmaceuticals (Basel). 2020;13: pubmed publisher
Vijayaraj P, Minasyan A, Durra A, Karumbayaram S, Mehrabi M, Aros C, et al. Modeling Progressive Fibrosis with Pluripotent Stem Cells Identifies an Anti-fibrotic Small Molecule. Cell Rep. 2019;29:3488-3505.e9 pubmed publisher
product information
master code :
AF6220
SKU :
AF6220
product name :
Human Pro Collagen I alpha 1 Antibody
unit size :
100 ug (also 25 ug)
description :
The Human Pro Collagen I alpha 1 Antibody from R&D Systems is a sheep polyclonal antibody to Collagen I alpha 1. This antibody reacts with human,mouse,primate - macaca mulatta (rhesus macaque),primate - papio anubis (olive baboon),xenograft. The Human Pro Collagen I alpha 1 Antibody has been validated for the following applications: Immunohistochemistry,Western Blot,Immunocytochemistry,Immunoprecipitation,Simple Western.
target :
Collagen I alpha 1
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Sheep
immunogen :
Chinese hamster ovary cell line CHO-derived recombinant human Collagen I, Gln23-Lys277, Gly1094-Leu1464, Accession # P02452
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Primate - Macaca mulatta (Rhesus Macaque),Primate - Papio anubis (Olive Baboon),Xenograft
specificity :
Detects human Pro-Collagen I alpha 1 in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant human COL3A1 is observed.
gene symbol :
COL1A1
top caption :
Detection of Human N-Pro Collagen I by Western Blot.
accessionNumbers :
P02452
applications :
Immunohistochemistry,Western Blot,Immunocytochemistry,Immunoprecipitation,Simple Western
USD :
499 USD
alt names :
Alpha-1 type I collagen, COL1A1, COL-IA1, Collagen 1, Collagen 1 alpha 1, collagen alpha 1 chain type I, collagen alpha-1(I) chain, collagen of skin, tendon and bone, alpha-1 chain, Collagen Type I Alpha 1 Chain, collagen, type I, alpha 1, Collagen1, Collagen-1, EDSARTH1, OI4, pro-alpha-1 collagen type 1, Type I Procollagen Alpha 1 Chain
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.