product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Caspase-1 Antibody
catalog :
AF6215
quantity :
100 ug (also 25 ug)
price :
479 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, rat
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
R&D Systems product webpage
citations: 3
Reference
Tsukalov I, S xe1 nchez Cerrillo I, Rajas O, Ávalos E, Iturricastillo G, Esparcia L, et al. NFκB and NLRP3/NLRC4 inflammasomes regulate differentiation, activation and functional properties of monocytes in response to distinct SARS-CoV-2 proteins. Nat Commun. 2024;15:2100 pubmed publisher
Brewer S, Twittenhoff C, Kortmann J, Brubaker S, Honeycutt J, Massis L, et al. A Salmonella Typhi RNA thermosensor regulates virulence factors and innate immune evasion in response to host temperature. PLoS Pathog. 2021;17:e1009345 pubmed publisher
Lê V, Dubois J, Couture C, Cavanagh M, Uyar O, Pizzorno A, et al. Human metapneumovirus activates NOD-like receptor protein 3 inflammasome via its small hydrophobic protein which plays a detrimental role during infection in mice. PLoS Pathog. 2019;15:e1007689 pubmed publisher
product information
master code :
AF6215
SKU :
AF6215
product name :
Human Caspase-1 Antibody
unit size :
100 ug (also 25 ug)
description :
The Human Caspase-1 Antibody from R&D Systems is a goat polyclonal antibody to Caspase-1. This antibody reacts with human,rat. The Human Caspase-1 Antibody has been validated for the following applications: Immunohistochemistry,Western Blot,Simple Western,Immunocytochemistry,Knockout Validated.
target :
Caspase-1
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
E. coli -derived recombinant human Caspase-1, Asn120-Asp297, Accession # P29466
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Rat
specificity :
Detects human Caspase-1 in Western blots.
gene symbol :
CASP1
Antibody validation :
Knockout/Knockdown
top caption :
Detection of Human Caspase-1 antibody by Western Blot.
accessionNumbers :
P29466
applications :
Immunohistochemistry,Western Blot,Simple Western,Immunocytochemistry,Knockout Validated
USD :
479 USD
alt names :
CASP1, CASP-1, CASP1 nirs variant 1, caspase 1, apoptosis-related cysteine peptidase, caspase-1, Caspase1, Caspase-1 subunit p10, Caspase-1 subunit p20, EC 3.4.22.36, EC:3.4.22.36, ICE, IL-1 beta-converting enzyme, IL1BC, IL-1BC, IL1BCE, IL1B-convertase, interleukin 1, beta, convertase, interleukin 1-B converting enzyme, Interleukin-1 beta convertase, Interleukin-1 beta-converting enzyme, p45
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.