product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human EOMES Antibody
catalog :
AF6166
quantity :
100 ug (also 25 ug)
price :
509 USD
clonality :
polyclonal
host :
domestic sheep
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 25
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; human; 1:200; fig s1c
Andrews M, Mukhtar T, Eze U, Simoneau C, Perez Y, Mostajo Radji M, et al. Tropism of SARS-CoV-2 for Developing Human Cortical Astrocytes. bioRxiv. 2021;: pubmed publisher
Noack F, Vangelisti S, Ditzer N, Chong F, Albert M, Bonev B. Joint epigenome profiling reveals cell-type-specific gene regulatory programmes in human cortical organoids. Nat Cell Biol. 2023;25:1873-1883 pubmed publisher
Chiaradia I, Imaz Rosshandler I, Nilges B, Boulanger J, Pellegrini L, Das R, et al. Tissue morphology influences the temporal program of human brain organoid development. Cell Stem Cell. 2023;30:1351-1367.e10 pubmed publisher
Perez Y, Velmeshev D, Wang L, White M, Siebert C, Baltazar J, et al. Single cell analysis of dup15q syndrome reveals developmental and postnatal molecular changes in autism. bioRxiv. 2023;: pubmed publisher
Sidhaye J, Trepte P, Sepke N, Novatchkova M, Schutzbier M, D xfc rnberger G, et al. Integrated transcriptome and proteome analysis reveals posttranscriptional regulation of ribosomal genes in human brain organoids. elife. 2023;12: pubmed publisher
Kr xe4 mer B, Nalin A, Ma F, Eickhoff S, Lutz P, Leonardelli S, et al. Single-cell RNA sequencing identifies a population of human liver-type ILC1s. Cell Rep. 2023;42:111937 pubmed publisher
Mesci P, de Souza J, Martin Sancho L, Macia A, Saleh A, Yin X, et al. SARS-CoV-2 infects human brain organoids causing cell death and loss of synapses that can be rescued by treatment with Sofosbuvir. PLoS Biol. 2022;20:e3001845 pubmed publisher
Kelava I, Chiaradia I, Pellegrini L, Kalinka A, Lancaster M. Androgens increase excitatory neurogenic potential in human brain organoids. Nature. 2022;602:112-116 pubmed publisher
Carpentieri J, Di Cicco A, Lampič M, Andreau D, Del Maestro L, el Marjou F, et al. Endosomal trafficking defects alter neural progenitor proliferation and cause microcephaly. Nat Commun. 2022;13:16 pubmed publisher
Yang L, Li Z, Liu G, Li X, Yang Z. Developmental Origins of Human Cortical Oligodendrocytes and Astrocytes. Neurosci Bull. 2022;38:47-68 pubmed publisher
Popova G, Soliman S, Kim C, Keefe M, Hennick K, Jain S, et al. Human microglia states are conserved across experimental models and regulate neural stem cell responses in chimeric organoids. Cell Stem Cell. 2021;28:2153-2166.e6 pubmed publisher
Ou M, Xiao Q, Ju X, Zeng P, Huang J, Sheng A, et al. The CTNNBIP1-CLSTN1 fusion transcript regulates human neocortical development. Cell Rep. 2021;35:109290 pubmed publisher
Kalusa M, Heinrich M, Sauerland C, Morawski M, Fietz S. Developmental Differences in Neocortex Neurogenesis and Maturation Between the Altricial Dwarf Rabbit and Precocial Guinea Pig. Front Neuroanat. 2021;15:678385 pubmed publisher
Benito Kwiecinski S, Giandomenico S, Sutcliffe M, Riis E, Freire Pritchett P, Kelava I, et al. An early cell shape transition drives evolutionary expansion of the human forebrain. Cell. 2021;184:2084-2102.e19 pubmed publisher
Eze U, Bhaduri A, Haeussler M, Nowakowski T, Kriegstein A. Single-cell atlas of early human brain development highlights heterogeneity of human neuroepithelial cells and early radial glia. Nat Neurosci. 2021;24:584-594 pubmed publisher
Pellegrini L, Albecka A, Mallery D, Kellner M, Paul D, Carter A, et al. SARS-CoV-2 Infects the Brain Choroid Plexus and Disrupts the Blood-CSF Barrier in Human Brain Organoids. Cell Stem Cell. 2020;27:951-961.e5 pubmed publisher
Andrews M, Subramanian L, Kriegstein A. mTOR signaling regulates the morphology and migration of outer radial glia in developing human cortex. elife. 2020;9: pubmed publisher
Huang W, Bhaduri A, Velmeshev D, Wang S, Wang L, Rottkamp C, et al. Origins and Proliferative States of Human Oligodendrocyte Precursor Cells. Cell. 2020;182:594-608.e11 pubmed publisher
Matsumoto N, Tanaka S, Horiike T, Shinmyo Y, Kawasaki H. A discrete subtype of neural progenitor crucial for cortical folding in the gyrencephalic mammalian brain. elife. 2020;9: pubmed publisher
Guven A, Kalebic N, Long K, Florio M, Vaid S, Brandl H, et al. Extracellular matrix-inducing Sox9 promotes both basal progenitor proliferation and gliogenesis in developing neocortex. elife. 2020;9: pubmed publisher
Fietz S, Namba T, Kirsten H, Huttner W, Lachmann R. Signs of Reduced Basal Progenitor Levels and Cortical Neurogenesis in Human Fetuses with Open Spina Bifida at 11-15 Weeks of Gestation. J Neurosci. 2020;40:1766-1777 pubmed publisher
Pasca A, Park J, Shin H, Qi Q, Revah O, Krasnoff R, et al. Human 3D cellular model of hypoxic brain injury of prematurity. Nat Med. 2019;: pubmed publisher
Pollen A, Bhaduri A, Andrews M, Nowakowski T, Meyerson O, Mostajo Radji M, et al. Establishing Cerebral Organoids as Models of Human-Specific Brain Evolution. Cell. 2019;176:743-756.e17 pubmed publisher
Barger N, Keiter J, Kreutz A, Krishnamurthy A, Weidenthaler C, Martinez Cerdeno V, et al. Microglia: An Intrinsic Component of the Proliferative Zones in the Fetal Rhesus Monkey (Macaca mulatta) Cerebral Cortex. Cereb Cortex. 2019;29:2782-2796 pubmed publisher
Raab S, Klingenstein M, Möller A, Illing A, Tosic J, Breunig M, et al. Reprogramming to pluripotency does not require transition through a primitive streak-like state. Sci Rep. 2017;7:16543 pubmed publisher
product information
brand :
R&D Systems
master code :
AF6166
SKU :
AF6166
product name :
Human EOMES Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Human EOMES Antibody from R&D Systems is a sheep polyclonal antibody to EOMES. This antibody reacts with guinea pig,human,mouse,rabbit. The Human EOMES Antibody has been validated for the following applications: Immunohistochemistry,Flow Cytometry,Western Blot,Immunocytochemistry,Intracellular Staining by Flow Cytometry,CyTOF-ready.
target :
EOMES
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 1 ug/mL, Intracellular Staining by Flow Cytometry 2.5 ug/10^6 cells, Immunocytochemistry 5-15 ug/mL, CyTOF-ready
host :
Sheep
immunogen :
E. coli -derived recombinant human EOMES, Gly471-Pro686, Accession # O95936
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse
specificity :
Detects human EOMES in Western blots.
gene symbol :
EOMES
top caption :
Detection of Human EOMES antibody by Western Blot.
accessionNumbers :
O95936
applications :
Intracellular Staining by Flow Cytometry,CyTOF-ready,Flow Cytometry,Immunohistochemistry,Western Blot,Immunocytochemistry
USD :
509 USD
alt names :
eomesodermin, eomesodermin (Xenopus laevis) homolog, t box, brain, 2, T-box brain protein 2, T-box brain2, TBR2, TBR-2, TBR2eomesodermin homolog, T-brain-2
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.